(47 nodes) Regulation of keratinocyte proliferation network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Nfatc1	Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (938 aa)
	Zeb1	Zinc finger E-box-binding homeobox 1. (1114 aa)
	Lrg1	Leucine-rich alpha-2-glycoprotein. (342 aa)
	Ift57	Intraflagellar transport protein 57 homolog. (272 aa)
	Trp63	Tumor protein 63 isoform X1. (680 aa)
	Snai2	Zinc finger protein SNAI2. (269 aa)
	Vdr	Vitamin D3 receptor. (423 aa)
	Slurp1	Secreted Ly-6/uPAR-related protein 1. (110 aa)
	Has2	Hyaluronan synthase 2. (552 aa)
	Ift88	Intraflagellar transport protein 88 homolog. (825 aa)
	Tgm1	Protein-glutamine gamma-glutamyltransferase K. (815 aa)
	Fgf10	Fibroblast growth factor 10. (209 aa)
	Ctsl	Cathepsin L2. (334 aa)
	Ptch1	Protein patched homolog 1. (1434 aa)
	Bcl11b	B-cell lymphoma/leukemia 11B isoform X1. (884 aa)
	Zfp36l1	MRNA decay activator protein ZFP36L1. (338 aa)
	Prkd1	LOW QUALITY PROTEIN: serine/threonine-protein kinase D1. (892 aa)
	Med1	Mediator of RNA polymerase II transcription subunit 1 isoform X1. (1583 aa)
	Stxbp4	Syntaxin-binding protein 4. (557 aa)
	Kif3a	Kinesin-like protein KIF3A isoform X1. (725 aa)
	Ptprk	Receptor-type tyrosine-protein phosphatase kappa. (1415 aa)
	Irf6	Interferon regulatory factor 6. (467 aa)
	Twist2	Twist-related protein 2. (160 aa)
	Cask	Calcium/calmodulin-dependent serine protein kinase. (920 aa)
	Ovol1	Putative transcription factor Ovo-like 1 isoform X1. (267 aa)
	Klf9	Krueppel-like factor 9/13/14/16. (244 aa)
	Mdk	Midkine isoform X1. (140 aa)
	Fgf7	Fibroblast growth factor 7. (194 aa)
	Ovol2	Transcription factor Ovo-like 2 isoform X1. (274 aa)
	Srsf6	Splicing factor, arginine/serine-rich 4/5/6. (339 aa)
	Ift52	Intraflagellar transport protein 52 homolog. (426 aa)
	Intu	Protein inturned. (942 aa)
	Ift80	Intraflagellar transport protein 80 homolog. (777 aa)
	Crnn	Cornulin-like. (520 aa)
	Notch2	Neurogenic locus notch homolog protein 2. (2471 aa)
	Kdf1	Keratinocyte differentiation factor 1. (397 aa)
	Sfn	14-3-3 protein sigma. (248 aa)
	MGP_CAROLIEiJ_P0067375	Intraflagellar transport protein 172 homolog. (207 aa)
	Reg3a	Regenerating islet-derived protein 3-alpha isoform X1. (175 aa)
	Reg3g	Regenerating islet-derived protein 3-gamma. (174 aa)
	Ift122	Intraflagellar transport protein 122 homolog isoform X1. (1241 aa)
	Zfp36	MRNA decay activator protein ZFP36. (319 aa)
	Fgfr2	Fibroblast growth factor receptor 2 isoform X1. (838 aa)
	Efnb2	Ephrin-B2. (336 aa)
	Cdh3	Cadherin 3, type 1, P-cadherin. (825 aa)
	Yap1	Transcriptional coactivator YAP1 isoform X1. (488 aa)
	Cd109	CD109 antigen. (1442 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cask	Stxbp4	MGP_CAROLIEiJ_P0091048	MGP_CAROLIEiJ_P0029174	Calcium/calmodulin-dependent serine protein kinase.	Syntaxin-binding protein 4.	0.507
Fgf10	Fgf7	MGP_CAROLIEiJ_P0035544	MGP_CAROLIEiJ_P0054343	Fibroblast growth factor 10.	Fibroblast growth factor 7.	0.485
Fgf10	Fgfr2	MGP_CAROLIEiJ_P0035544	MGP_CAROLIEiJ_P0082706	Fibroblast growth factor 10.	Fibroblast growth factor receptor 2 isoform X1.	0.998
Fgf10	Ptch1	MGP_CAROLIEiJ_P0035544	MGP_CAROLIEiJ_P0034706	Fibroblast growth factor 10.	Protein patched homolog 1.	0.572
Fgf7	Fgf10	MGP_CAROLIEiJ_P0054343	MGP_CAROLIEiJ_P0035544	Fibroblast growth factor 7.	Fibroblast growth factor 10.	0.485
Fgf7	Fgfr2	MGP_CAROLIEiJ_P0054343	MGP_CAROLIEiJ_P0082706	Fibroblast growth factor 7.	Fibroblast growth factor receptor 2 isoform X1.	0.996
Fgfr2	Fgf10	MGP_CAROLIEiJ_P0082706	MGP_CAROLIEiJ_P0035544	Fibroblast growth factor receptor 2 isoform X1.	Fibroblast growth factor 10.	0.998
Fgfr2	Fgf7	MGP_CAROLIEiJ_P0082706	MGP_CAROLIEiJ_P0054343	Fibroblast growth factor receptor 2 isoform X1.	Fibroblast growth factor 7.	0.996
Has2	Ift88	MGP_CAROLIEiJ_P0038237	MGP_CAROLIEiJ_P0036952	Hyaluronan synthase 2.	Intraflagellar transport protein 88 homolog.	0.414
Ift122	Ift52	MGP_CAROLIEiJ_P0075608	MGP_CAROLIEiJ_P0055937	Intraflagellar transport protein 122 homolog isoform X1.	Intraflagellar transport protein 52 homolog.	0.946
Ift122	Ift57	MGP_CAROLIEiJ_P0075608	MGP_CAROLIEiJ_P0041828	Intraflagellar transport protein 122 homolog isoform X1.	Intraflagellar transport protein 57 homolog.	0.947
Ift122	Ift80	MGP_CAROLIEiJ_P0075608	MGP_CAROLIEiJ_P0057960	Intraflagellar transport protein 122 homolog isoform X1.	Intraflagellar transport protein 80 homolog.	0.933
Ift122	Ift88	MGP_CAROLIEiJ_P0075608	MGP_CAROLIEiJ_P0036952	Intraflagellar transport protein 122 homolog isoform X1.	Intraflagellar transport protein 88 homolog.	0.958
Ift122	Kif3a	MGP_CAROLIEiJ_P0075608	MGP_CAROLIEiJ_P0026635	Intraflagellar transport protein 122 homolog isoform X1.	Kinesin-like protein KIF3A isoform X1.	0.658
Ift122	MGP_CAROLIEiJ_P0067375	MGP_CAROLIEiJ_P0075608	MGP_CAROLIEiJ_P0067375	Intraflagellar transport protein 122 homolog isoform X1.	Intraflagellar transport protein 172 homolog.	0.949
Ift52	Ift122	MGP_CAROLIEiJ_P0055937	MGP_CAROLIEiJ_P0075608	Intraflagellar transport protein 52 homolog.	Intraflagellar transport protein 122 homolog isoform X1.	0.946
Ift52	Ift57	MGP_CAROLIEiJ_P0055937	MGP_CAROLIEiJ_P0041828	Intraflagellar transport protein 52 homolog.	Intraflagellar transport protein 57 homolog.	0.998
Ift52	Ift80	MGP_CAROLIEiJ_P0055937	MGP_CAROLIEiJ_P0057960	Intraflagellar transport protein 52 homolog.	Intraflagellar transport protein 80 homolog.	0.991
Ift52	Ift88	MGP_CAROLIEiJ_P0055937	MGP_CAROLIEiJ_P0036952	Intraflagellar transport protein 52 homolog.	Intraflagellar transport protein 88 homolog.	0.997
Ift52	Intu	MGP_CAROLIEiJ_P0055937	MGP_CAROLIEiJ_P0057462	Intraflagellar transport protein 52 homolog.	Protein inturned.	0.551