(42 nodes) Regulation of fatty acid oxidation network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Mtor	Serine/threonine-protein kinase mTOR. (2549 aa)
	Abcd1	ATP-binding cassette sub-family D member 1 isoform X1. (736 aa)
	Mlycd	Malonyl-CoA decarboxylase, mitochondrial. (492 aa)
	Lonp2	Lon protease homolog 2, peroxisomal. (852 aa)
	Irs2	Insulin receptor substrate 2. (1324 aa)
	Nucb2	Nucleobindin-2. (420 aa)
	Dgat2	Diacylglycerol O-acyltransferase 2. (368 aa)
	Akt2	RAC-beta serine/threonine-protein kinase. (481 aa)
	Etfbkmt	Electron transfer flavoprotein beta subunit lysine methyltransferase isoform X1. (255 aa)
	Pparg	Peroxisome proliferator-activated receptor gamma isoform X1. (505 aa)
	Fabp1	Fatty acid-binding protein 1, liver. (127 aa)
	Pdk4	Pyruvate dehydrogenase kinase, isozyme 4. (412 aa)
	Sirt4	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial. (333 aa)
	Acacb	Acetyl-CoA carboxylase / biotin carboxylase 2. (2423 aa)
	Ppargc1a	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (796 aa)
	Fabp3	Fatty acid-binding protein 3, muscle and heart. (133 aa)
	Mfsd2a	Sodium-dependent lysophosphatidylcholine symporter 1. (534 aa)
	Nr4a3	Nuclear receptor subfamily 4 group A member 3. (656 aa)
	Cnr1	Cannabinoid receptor 1 isoform X1. (473 aa)
	Mtln	Mitoregulin. (56 aa)
	Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11. (1321 aa)
	Obp2a	Odorant-binding protein 2a. (175 aa)
	Acsl5	Long-chain-fatty-acid--CoA ligase 5 isoform X1. (683 aa)
	Cpt1a	Carnitine O-palmitoyltransferase 1, liver isoform. (773 aa)
	Plin5	Perilipin-5. (463 aa)
	Ppard	Peroxisome proliferator-activated receptor delta. (440 aa)
	Abcd2	ATP-binding cassette, subfamily D (ALD), member 2. (741 aa)
	Ppara	Peroxisome proliferator-activated receptor alpha. (468 aa)
	Dgat1	Diacylglycerol O-acyltransferase 1 isoform X1. (504 aa)
	Akt1	RAC-alpha serine/threonine-protein kinase isoform X1. (480 aa)
	Twist1	Twist-related protein 1. (206 aa)
	Sox9	Transcription factor SOX9 (SOX group E). (507 aa)
	Acadvl	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial. (656 aa)
	C1qtnf2	Complement C1q tumor necrosis factor-related protein 2. (324 aa)
	Appl2	DCC-interacting protein 13-beta isoform X1. (662 aa)
	Tysnd1	Peroxisomal leader peptide-processing protease. (568 aa)
	Fmo2	Dimethylaniline monooxygenase [N-oxide-forming] 2. (535 aa)
	Fmo1	Dimethylaniline monooxygenase [N-oxide-forming] 1. (532 aa)
	Fmo4	Dimethylaniline monooxygenase [N-oxide-forming] 4. (560 aa)
	Dbi	Diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein). (87 aa)
	Irs1	Insulin receptor substrate 1. (1230 aa)
	Acadl	Long-chain specific acyl-CoA dehydrogenase, mitochondrial. (430 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abcb11	Ppara	MGP_CAROLIEiJ_P0052109	MGP_CAROLIEiJ_P0039338	ATP-binding cassette, subfamily B (MDR/TAP), member 11.	Peroxisome proliferator-activated receptor alpha.	0.464
Abcd1	Abcd2	MGP_CAROLIEiJ_P0091705	MGP_CAROLIEiJ_P0039528	ATP-binding cassette sub-family D member 1 isoform X1.	ATP-binding cassette, subfamily D (ALD), member 2.	0.911
Abcd2	Abcd1	MGP_CAROLIEiJ_P0039528	MGP_CAROLIEiJ_P0091705	ATP-binding cassette, subfamily D (ALD), member 2.	ATP-binding cassette sub-family D member 1 isoform X1.	0.911
Acacb	Acadl	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0018123	Acetyl-CoA carboxylase / biotin carboxylase 2.	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	0.501
Acacb	Acadvl	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0027739	Acetyl-CoA carboxylase / biotin carboxylase 2.	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial.	0.461
Acacb	Cpt1a	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0047331	Acetyl-CoA carboxylase / biotin carboxylase 2.	Carnitine O-palmitoyltransferase 1, liver isoform.	0.953
Acacb	Dgat1	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0038682	Acetyl-CoA carboxylase / biotin carboxylase 2.	Diacylglycerol O-acyltransferase 1 isoform X1.	0.500
Acacb	Dgat2	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0080822	Acetyl-CoA carboxylase / biotin carboxylase 2.	Diacylglycerol O-acyltransferase 2.	0.506
Acacb	Mlycd	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0086176	Acetyl-CoA carboxylase / biotin carboxylase 2.	Malonyl-CoA decarboxylase, mitochondrial.	0.936
Acacb	Ppara	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0039338	Acetyl-CoA carboxylase / biotin carboxylase 2.	Peroxisome proliferator-activated receptor alpha.	0.502
Acacb	Ppargc1a	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0068146	Acetyl-CoA carboxylase / biotin carboxylase 2.	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1.	0.412
Acadl	Acacb	MGP_CAROLIEiJ_P0018123	MGP_CAROLIEiJ_P0069975	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	Acetyl-CoA carboxylase / biotin carboxylase 2.	0.501
Acadl	Acadvl	MGP_CAROLIEiJ_P0018123	MGP_CAROLIEiJ_P0027739	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial.	0.939
Acadl	Acsl5	MGP_CAROLIEiJ_P0018123	MGP_CAROLIEiJ_P0049156	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	Long-chain-fatty-acid--CoA ligase 5 isoform X1.	0.551
Acadl	Cpt1a	MGP_CAROLIEiJ_P0018123	MGP_CAROLIEiJ_P0047331	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	Carnitine O-palmitoyltransferase 1, liver isoform.	0.596
Acadl	Dbi	MGP_CAROLIEiJ_P0018123	MGP_CAROLIEiJ_P0019507	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	Diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein).	0.408
Acadl	Fabp3	MGP_CAROLIEiJ_P0018123	MGP_CAROLIEiJ_P0064738	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	Fatty acid-binding protein 3, muscle and heart.	0.444
Acadl	Mlycd	MGP_CAROLIEiJ_P0018123	MGP_CAROLIEiJ_P0086176	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	Malonyl-CoA decarboxylase, mitochondrial.	0.498
Acadl	Pdk4	MGP_CAROLIEiJ_P0018123	MGP_CAROLIEiJ_P0072515	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	Pyruvate dehydrogenase kinase, isozyme 4.	0.492
Acadl	Ppara	MGP_CAROLIEiJ_P0018123	MGP_CAROLIEiJ_P0039338	Long-chain specific acyl-CoA dehydrogenase, mitochondrial.	Peroxisome proliferator-activated receptor alpha.	0.596