(20 nodes) Enteric nervous system development network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Sox8	Transcription factor SOX7/8/10/18 (SOX group E/F). (464 aa)
	Arx	Homeobox protein aristaless-related. (565 aa)
	Hlx	H2.0-like homeobox protein. (476 aa)
	Ascl1	Achaete-scute complex protein. (231 aa)
	Kif26a	Kinesin-like protein KIF26A isoform X1. (1884 aa)
	Ednrb	Endothelin receptor type B. (442 aa)
	Gdnf	Glial cell line-derived neurotrophic factor isoform X1. (240 aa)
	Sox10	Transcription factor SOX7/8/10/18 (SOX group E/F). (466 aa)
	Phactr4	Phosphatase and actin regulator 4. (681 aa)
	Phox2b	Paired mesoderm homeobox protein 2B. (314 aa)
	Tlx2	T-cell leukemia homeobox protein 2. (284 aa)
	MGP_CAROLIEiJ_P0075713	annotation not available (1024 aa)
	Ntf3	Neurotrophin-3 isoform X1. (271 aa)
	Phox2a	Paired mesoderm homeobox protein 2A. (280 aa)
	Isx	Intestine-specific homeobox isoform X1. (242 aa)
	Ednra	Endothelin receptor type A. (427 aa)
	Gm9	Uncharacterized protein LOC110287406. (157 aa)
	Rhox5	Homeobox protein Rhox5 isoform X1. (213 aa)
	Rhox10	Rhox homeobox family member 1-like. (201 aa)
	Rhox11	Rhox homeobox family member 1-like. (209 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arx	Tlx2	MGP_CAROLIEiJ_P0092095	MGP_CAROLIEiJ_P0074504	Homeobox protein aristaless-related.	T-cell leukemia homeobox protein 2.	0.405
Ascl1	Phox2a	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0081015	Achaete-scute complex protein.	Paired mesoderm homeobox protein 2A.	0.527
Ascl1	Phox2b	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0068439	Achaete-scute complex protein.	Paired mesoderm homeobox protein 2B.	0.569
Ascl1	Sox10	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0038919	Achaete-scute complex protein.	Transcription factor SOX7/8/10/18 (SOX group E/F).	0.556
Ednra	Ednrb	MGP_CAROLIEiJ_P0085065	MGP_CAROLIEiJ_P0037585	Endothelin receptor type A.	Endothelin receptor type B.	0.980
Ednrb	Ednra	MGP_CAROLIEiJ_P0037585	MGP_CAROLIEiJ_P0085065	Endothelin receptor type B.	Endothelin receptor type A.	0.980
Ednrb	Gdnf	MGP_CAROLIEiJ_P0037585	MGP_CAROLIEiJ_P0037794	Endothelin receptor type B.	Glial cell line-derived neurotrophic factor isoform X1.	0.406
Ednrb	MGP_CAROLIEiJ_P0075713	MGP_CAROLIEiJ_P0037585	MGP_CAROLIEiJ_P0075713	Endothelin receptor type B.	annotation not available	0.504
Ednrb	Phox2b	MGP_CAROLIEiJ_P0037585	MGP_CAROLIEiJ_P0068439	Endothelin receptor type B.	Paired mesoderm homeobox protein 2B.	0.499
Ednrb	Sox10	MGP_CAROLIEiJ_P0037585	MGP_CAROLIEiJ_P0038919	Endothelin receptor type B.	Transcription factor SOX7/8/10/18 (SOX group E/F).	0.590
Gdnf	Ednrb	MGP_CAROLIEiJ_P0037794	MGP_CAROLIEiJ_P0037585	Glial cell line-derived neurotrophic factor isoform X1.	Endothelin receptor type B.	0.406
Gdnf	MGP_CAROLIEiJ_P0075713	MGP_CAROLIEiJ_P0037794	MGP_CAROLIEiJ_P0075713	Glial cell line-derived neurotrophic factor isoform X1.	annotation not available	0.965
Gdnf	Ntf3	MGP_CAROLIEiJ_P0037794	MGP_CAROLIEiJ_P0076163	Glial cell line-derived neurotrophic factor isoform X1.	Neurotrophin-3 isoform X1.	0.726
Gdnf	Phox2b	MGP_CAROLIEiJ_P0037794	MGP_CAROLIEiJ_P0068439	Glial cell line-derived neurotrophic factor isoform X1.	Paired mesoderm homeobox protein 2B.	0.451
Gdnf	Sox10	MGP_CAROLIEiJ_P0037794	MGP_CAROLIEiJ_P0038919	Glial cell line-derived neurotrophic factor isoform X1.	Transcription factor SOX7/8/10/18 (SOX group E/F).	0.517
Gm9	Tlx2	MGP_CAROLIEiJ_P0091230	MGP_CAROLIEiJ_P0074504	Uncharacterized protein LOC110287406.	T-cell leukemia homeobox protein 2.	0.405
MGP_CAROLIEiJ_P0075713	Ednrb	MGP_CAROLIEiJ_P0075713	MGP_CAROLIEiJ_P0037585	annotation not available	Endothelin receptor type B.	0.504
MGP_CAROLIEiJ_P0075713	Gdnf	MGP_CAROLIEiJ_P0075713	MGP_CAROLIEiJ_P0037794	annotation not available	Glial cell line-derived neurotrophic factor isoform X1.	0.965
MGP_CAROLIEiJ_P0075713	Ntf3	MGP_CAROLIEiJ_P0075713	MGP_CAROLIEiJ_P0076163	annotation not available	Neurotrophin-3 isoform X1.	0.506
MGP_CAROLIEiJ_P0075713	Phox2b	MGP_CAROLIEiJ_P0075713	MGP_CAROLIEiJ_P0068439	annotation not available	Paired mesoderm homeobox protein 2B.	0.504