(63 nodes) Response to axon injury network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Gipr	Gastric inhibitory polypeptide receptor. (460 aa)
	Apoe	Apolipoprotein E. (312 aa)
	Tyrobp	TYRO protein tyrosine kinase binding protein. (114 aa)
	Mag	Myelin-associated glycoprotein isoform X1. (626 aa)
	Bax	Apoptosis regulator BAX isoform X1. (192 aa)
	Ntrk3	Neurotrophic tyrosine kinase, receptor type 3. (864 aa)
	Folr1	Folate receptor alpha. (255 aa)
	Bnip3	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (187 aa)
	Mmp2	Matrix metalloproteinase-2 (gelatinase A). (662 aa)
	Plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1. (1265 aa)
	Apoa4	Apolipoprotein A-IV. (395 aa)
	Drd2	D(2) dopamine receptor. (444 aa)
	Map2k1	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1. (393 aa)
	Dag1	Dystroglycan 1. (893 aa)
	Lamb2	Laminin subunit beta-2. (1799 aa)
	Cspg5	Chondroitin sulfate proteoglycan 5 isoform X1. (566 aa)
	Bex1	Protein BEX1. (128 aa)
	Chl1	Neural cell adhesion molecule L1-like protein isoform X1. (1209 aa)
	Ctnna2	Catenin alpha-2 isoform X1. (966 aa)
	Epo	Erythropoietin isoform X1. (192 aa)
	P2rx4	P2X purinoceptor 4. (388 aa)
	Fgfr3	Fibroblast growth factor receptor 3. (802 aa)
	Shh	Sonic hedgehog protein isoform X1. (438 aa)
	Jun	Transcription factor AP-1. (334 aa)
	Tnc	Tenascin isoform X1. (2110 aa)
	Ntrk1	High affinity nerve growth factor receptor isoform X1. (799 aa)
	P2ry12	P2Y purinoceptor 12. (347 aa)
	Fgf2	Fibroblast growth factor 2 isoform X1. (154 aa)
	Kcnb1	Potassium voltage-gated channel Shab-related subfamily B member 1. (857 aa)
	Matn4	Matrilin-4 isoform X1. (624 aa)
	Flrt3	Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
	Rtn4rl2	Reticulon-4 receptor-like 2. (426 aa)
	Morn4	MORN repeat-containing protein 4. (146 aa)
	Jak2	Tyrosine-protein kinase JAK2. (1132 aa)
	Slc1a1	Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter), member 1. (523 aa)
	Dpysl3	LOW QUALITY PROTEIN: dihydropyrimidinase-related protein 3. (693 aa)
	Ctnna1	Catenin alpha-1 isoform X1. (906 aa)
	Nrep	Neuronal regeneration-related protein. (68 aa)
	Trem2	Triggering receptor expressed on myeloid cells 2 isoform X1. (249 aa)
	Mapk8ip3	C-Jun-amino-terminal kinase-interacting protein 3 isoform X1. (1345 aa)
	Sod1	Superoxide dismutase, Cu-Zn family. (154 aa)
	Gap43	Neuromodulin. (227 aa)
	Apod	Apolipoprotein D and lipocalin family protein. (189 aa)
	Tspo	Translocator protein. (169 aa)
	Rangap1	Ran GTPase-activating protein 1 isoform X1. (589 aa)
	Txn2	Thioredoxin 2. (166 aa)
	Matn2	Matrilin-2 isoform X1. (957 aa)
	Nefl	Neurofilament light polypeptide. (543 aa)
	Isl1	Insulin gene enhancer protein ISL-1 isoform X1. (349 aa)
	Map1b	Microtubule-associated protein 1B. (2463 aa)
	Dhfr	Dihydrofolate reductase. (187 aa)
	Pcsk1	Proprotein convertase subtilisin/kexin type 1. (753 aa)
	Mtr	5-methyltetrahydrofolate--homocysteine methyltransferase. (1253 aa)
	Erbb2	Receptor tyrosine-protein kinase erbB-2. (1258 aa)
	Gip	Gastric inhibitory polypeptide. (144 aa)
	Sarm1	Sterile alpha and TIR motif-containing protein 1. (724 aa)
	Nefh	Neurofilament heavy polypeptide. (1037 aa)
	Cdk1	Cyclin-dependent kinase 1. (297 aa)
	Arg1	Arginase-1. (323 aa)
	Enpp1	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1. (906 aa)
	Kcnk2	Potassium channel subfamily K member 2 isoform X1. (426 aa)
	Tnr	Tenascin-R isoform X1. (1358 aa)
	Bcl2	Apoptosis regulator Bcl-2. (236 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Apoa4	Apod	MGP_CAROLIEiJ_P0087693	MGP_CAROLIEiJ_P0041212	Apolipoprotein A-IV.	Apolipoprotein D and lipocalin family protein.	0.642
Apoa4	Apoe	MGP_CAROLIEiJ_P0087693	MGP_CAROLIEiJ_P0077810	Apolipoprotein A-IV.	Apolipoprotein E.	0.924
Apod	Apoa4	MGP_CAROLIEiJ_P0041212	MGP_CAROLIEiJ_P0087693	Apolipoprotein D and lipocalin family protein.	Apolipoprotein A-IV.	0.642
Apod	Apoe	MGP_CAROLIEiJ_P0041212	MGP_CAROLIEiJ_P0077810	Apolipoprotein D and lipocalin family protein.	Apolipoprotein E.	0.610
Apoe	Apoa4	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0087693	Apolipoprotein E.	Apolipoprotein A-IV.	0.924
Apoe	Apod	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0041212	Apolipoprotein E.	Apolipoprotein D and lipocalin family protein.	0.610
Apoe	Bcl2	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0019368	Apolipoprotein E.	Apoptosis regulator Bcl-2.	0.461
Apoe	Jun	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0062982	Apolipoprotein E.	Transcription factor AP-1.	0.454
Apoe	Mmp2	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0085518	Apolipoprotein E.	Matrix metalloproteinase-2 (gelatinase A).	0.469
Apoe	P2ry12	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0057787	Apolipoprotein E.	P2Y purinoceptor 12.	0.463
Apoe	Sod1	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0042211	Apolipoprotein E.	Superoxide dismutase, Cu-Zn family.	0.431
Apoe	Trem2	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0045188	Apolipoprotein E.	Triggering receptor expressed on myeloid cells 2 isoform X1.	0.898
Apoe	Tspo	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0039258	Apolipoprotein E.	Translocator protein.	0.493
Apoe	Tyrobp	MGP_CAROLIEiJ_P0077810	MGP_CAROLIEiJ_P0078658	Apolipoprotein E.	TYRO protein tyrosine kinase binding protein.	0.534
Arg1	Trem2	MGP_CAROLIEiJ_P0022519	MGP_CAROLIEiJ_P0045188	Arginase-1.	Triggering receptor expressed on myeloid cells 2 isoform X1.	0.407
Bax	Bcl2	MGP_CAROLIEiJ_P0079525	MGP_CAROLIEiJ_P0019368	Apoptosis regulator BAX isoform X1.	Apoptosis regulator Bcl-2.	0.997
Bax	Jun	MGP_CAROLIEiJ_P0079525	MGP_CAROLIEiJ_P0062982	Apoptosis regulator BAX isoform X1.	Transcription factor AP-1.	0.412
Bax	Tspo	MGP_CAROLIEiJ_P0079525	MGP_CAROLIEiJ_P0039258	Apoptosis regulator BAX isoform X1.	Translocator protein.	0.439
Bcl2	Apoe	MGP_CAROLIEiJ_P0019368	MGP_CAROLIEiJ_P0077810	Apoptosis regulator Bcl-2.	Apolipoprotein E.	0.461
Bcl2	Bax	MGP_CAROLIEiJ_P0019368	MGP_CAROLIEiJ_P0079525	Apoptosis regulator Bcl-2.	Apoptosis regulator BAX isoform X1.	0.997