(23 nodes) White fat cell differentiation network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Per2	Period circadian protein homolog 2. (1257 aa)
	Zfp423	Zinc finger protein 423 isoform X1. (1292 aa)
	Ctbp2	C-terminal-binding protein 2 isoform X1. (988 aa)
	Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha. (359 aa)
	Pparg	Peroxisome proliferator-activated receptor gamma isoform X1. (505 aa)
	Creb5	Cyclic AMP-responsive element-binding protein 5 isoform X1. (513 aa)
	Ncor2	Nuclear receptor corepressor 2 isoform X1. (2507 aa)
	Pdgfra	Platelet-derived growth factor receptor alpha isoform X1. (1089 aa)
	Ctbp1	C-terminal-binding protein 1 isoform X1. (441 aa)
	Prdm16	PR domain zinc finger protein 16. (1276 aa)
	Tbl1xr1	F-box-like/WD repeat-containing protein TBL1XR1 isoform X1. (514 aa)
	Fabp4	Fatty acid-binding protein 4, adipocyte. (132 aa)
	Adig	Adipogenin. (80 aa)
	Atf2	Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (487 aa)
	Scd1	Stearoyl-CoA desaturase (Delta-9 desaturase). (358 aa)
	Ffar4	Free fatty acid receptor 4. (361 aa)
	Snai2	Zinc finger protein SNAI2. (269 aa)
	Pnpla3	Patatin-like phospholipase domain-containing protein 3 isoform X1. (387 aa)
	Retreg1	Reticulophagy receptor FAM134B isoform X1. (480 aa)
	Fgf10	Fibroblast growth factor 10. (209 aa)
	Id2	DNA-binding protein inhibitor ID-2. (134 aa)
	Wfdc21	Protein Wfdc21. (63 aa)
	Sirt1	NAD-dependent protein deacetylase sirtuin-1 isoform X1. (734 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atf2	Creb5	MGP_CAROLIEiJ_P0052340	MGP_CAROLIEiJ_P0073893	Cyclic AMP-dependent transcription factor ATF-2 isoform X1.	Cyclic AMP-responsive element-binding protein 5 isoform X1.	0.959
Atf2	Pparg	MGP_CAROLIEiJ_P0052340	MGP_CAROLIEiJ_P0075565	Cyclic AMP-dependent transcription factor ATF-2 isoform X1.	Peroxisome proliferator-activated receptor gamma isoform X1.	0.400
Cebpa	Ctbp2	MGP_CAROLIEiJ_P0078993	MGP_CAROLIEiJ_P0082832	CCAAT/enhancer binding protein (C/EBP), alpha.	C-terminal-binding protein 2 isoform X1.	0.412
Cebpa	Fabp4	MGP_CAROLIEiJ_P0078993	MGP_CAROLIEiJ_P0056910	CCAAT/enhancer binding protein (C/EBP), alpha.	Fatty acid-binding protein 4, adipocyte.	0.707
Cebpa	Per2	MGP_CAROLIEiJ_P0078993	MGP_CAROLIEiJ_P0019091	CCAAT/enhancer binding protein (C/EBP), alpha.	Period circadian protein homolog 2.	0.924
Cebpa	Pparg	MGP_CAROLIEiJ_P0078993	MGP_CAROLIEiJ_P0075565	CCAAT/enhancer binding protein (C/EBP), alpha.	Peroxisome proliferator-activated receptor gamma isoform X1.	0.890
Cebpa	Prdm16	MGP_CAROLIEiJ_P0078993	MGP_CAROLIEiJ_P0066184	CCAAT/enhancer binding protein (C/EBP), alpha.	PR domain zinc finger protein 16.	0.594
Cebpa	Scd1	MGP_CAROLIEiJ_P0078993	MGP_CAROLIEiJ_P0048912	CCAAT/enhancer binding protein (C/EBP), alpha.	Stearoyl-CoA desaturase (Delta-9 desaturase).	0.558
Cebpa	Sirt1	MGP_CAROLIEiJ_P0078993	MGP_CAROLIEiJ_P0023179	CCAAT/enhancer binding protein (C/EBP), alpha.	NAD-dependent protein deacetylase sirtuin-1 isoform X1.	0.617
Cebpa	Zfp423	MGP_CAROLIEiJ_P0078993	MGP_CAROLIEiJ_P0085446	CCAAT/enhancer binding protein (C/EBP), alpha.	Zinc finger protein 423 isoform X1.	0.497
Creb5	Atf2	MGP_CAROLIEiJ_P0073893	MGP_CAROLIEiJ_P0052340	Cyclic AMP-responsive element-binding protein 5 isoform X1.	Cyclic AMP-dependent transcription factor ATF-2 isoform X1.	0.959
Ctbp1	Ctbp2	MGP_CAROLIEiJ_P0067515	MGP_CAROLIEiJ_P0082832	C-terminal-binding protein 1 isoform X1.	C-terminal-binding protein 2 isoform X1.	0.992
Ctbp1	Prdm16	MGP_CAROLIEiJ_P0067515	MGP_CAROLIEiJ_P0066184	C-terminal-binding protein 1 isoform X1.	PR domain zinc finger protein 16.	0.806
Ctbp1	Sirt1	MGP_CAROLIEiJ_P0067515	MGP_CAROLIEiJ_P0023179	C-terminal-binding protein 1 isoform X1.	NAD-dependent protein deacetylase sirtuin-1 isoform X1.	0.515
Ctbp1	Snai2	MGP_CAROLIEiJ_P0067515	MGP_CAROLIEiJ_P0040496	C-terminal-binding protein 1 isoform X1.	Zinc finger protein SNAI2.	0.691
Ctbp2	Cebpa	MGP_CAROLIEiJ_P0082832	MGP_CAROLIEiJ_P0078993	C-terminal-binding protein 2 isoform X1.	CCAAT/enhancer binding protein (C/EBP), alpha.	0.412
Ctbp2	Ctbp1	MGP_CAROLIEiJ_P0082832	MGP_CAROLIEiJ_P0067515	C-terminal-binding protein 2 isoform X1.	C-terminal-binding protein 1 isoform X1.	0.992
Ctbp2	Ncor2	MGP_CAROLIEiJ_P0082832	MGP_CAROLIEiJ_P0070928	C-terminal-binding protein 2 isoform X1.	Nuclear receptor corepressor 2 isoform X1.	0.545
Ctbp2	Prdm16	MGP_CAROLIEiJ_P0082832	MGP_CAROLIEiJ_P0066184	C-terminal-binding protein 2 isoform X1.	PR domain zinc finger protein 16.	0.790
Fabp4	Cebpa	MGP_CAROLIEiJ_P0056910	MGP_CAROLIEiJ_P0078993	Fatty acid-binding protein 4, adipocyte.	CCAAT/enhancer binding protein (C/EBP), alpha.	0.707