(60 nodes) Myosin complex network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Myo1c	Unconventional myosin-Ic isoform X1. (1063 aa)
	Myl3	Myosin light chain 3. (204 aa)
	Myo6	Unconventional myosin-VI. (1294 aa)
	Myo5c	Unconventional myosin-Vc. (1742 aa)
	Myo5a	Unconventional myosin-Va. (1855 aa)
	Myo1e	Unconventional myosin-Ie. (1107 aa)
	Myo9a	Unconventional myosin-IXa isoform X1. (2631 aa)
	Gipc1	PDZ domain-containing protein GIPC1. (333 aa)
	Myo9b	Unconventional myosin-IXb isoform X1. (2117 aa)
	Myo16	Unconventional myosin-XVI. (1906 aa)
	Mylpf	Myosin regulatory light chain 2, skeletal muscle isoform isoform X1. (169 aa)
	Myo7a	Unconventional myosin-VIIa isoform X1. (2215 aa)
	Myh14-2	Myosin heavy chain 14. (1998 aa)
	Myh14	Myosin heavy chain 9/10/11/14. (2018 aa)
	Vasp	Vasodilator-stimulated phosphoprotein. (375 aa)
	Ssmem1	Serine-rich single-pass membrane protein 1 isoform X1. (244 aa)
	Myl2	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
	Myo18b	Unconventional myosin-XVIIIb. (2558 aa)
	Limch1	LIM and calponin homology domains-containing protein 1 isoform X1. (1068 aa)
	Whrn	Whirlin isoform X1. (930 aa)
	Myl9	Myosin regulatory light polypeptide 9. (172 aa)
	Myh7b	Myosin heavy chain 1/2/3/4/8/13/7B/15. (1941 aa)
	Bmf	Bcl-2-modifying factor. (271 aa)
	Ttn	Titin. (32000 aa)
	Wipf1	WAS/WASL-interacting protein family member 1. (491 aa)
	Myo3b	Myosin-IIIb. (1333 aa)
	Myo3a	Myosin-IIIa. (1622 aa)
	Myo5b	Unconventional myosin-Vb isoform X1. (1844 aa)
	Myl12a	Myosin regulatory light chain RLC-A. (172 aa)
	Myl12b	Myosin regulatory light chain 12B. (172 aa)
	Myo1f	Unconventional myosin-If. (1098 aa)
	Myh15	Myosin heavy chain 1/2/3/4/8/13/7B/15. (1925 aa)
	Myh11	Myosin heavy chain 9/10/11/14. (1979 aa)
	Myh9	Myosin heavy chain 9/10/11/14. (1960 aa)
	Myo10	Unconventional myosin-X. (2062 aa)
	Dab2	Disabled homolog 2. (766 aa)
	Myh7	Myosin heavy chain 6/7. (1935 aa)
	Myh6	Myosin heavy chain 6/7. (1954 aa)
	Ism2	Isthmin-2. (491 aa)
	Myl4	Myosin light chain 4. (192 aa)
	Dynll2	Dynein light chain 2, cytoplasmic. (89 aa)
	Myo1d	Unconventional myosin-Id. (1006 aa)
	Myo18a	Unconventional myosin-XVIIIa isoform X1. (2083 aa)
	Myh10	Myosin heavy chain 9/10/11/14. (1965 aa)
	Myh8	Myosin heavy chain 1/2/3/4/8/13/7B/15. (1937 aa)
	Myh4	Myosin heavy chain 1/2/3/4/8/13/7B/15. (1939 aa)
	MGP_CAROLIEiJ_P0027339	annotation not available (95 aa)
	Myh2	Myosin, heavy polypeptide 2, skeletal muscle, adult. (2025 aa)
	Myh3	Myosin, heavy polypeptide 3, skeletal muscle, embryonic. (1800 aa)
	Myo15	Unconventional myosin-XV isoform X1. (3514 aa)
	Myo1g	Unconventional myosin-Ig. (1024 aa)
	Myl7	Myosin regulatory light chain 2, atrial isoform. (175 aa)
	Myl6b	Myosin light chain 6B. (207 aa)
	Myl6	Myosin light polypeptide 6 isoform X1. (151 aa)
	Myo1a	Unconventional myosin-Ia. (1043 aa)
	Spata17	Spermatogenesis-associated protein 17 isoform X1. (379 aa)
	Spata3	Spermatogenesis-associated protein 3 isoform X1. (193 aa)
	Nyap2	Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform X1. (716 aa)
	Myl1	Myosin light chain 1/3, skeletal muscle isoform isoform X1. (188 aa)
	Myo1b	Unconventional myosin-Ib isoform X1. (1136 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bmf	Dynll2	MGP_CAROLIEiJ_P0053744	MGP_CAROLIEiJ_P0029106	Bcl-2-modifying factor.	Dynein light chain 2, cytoplasmic.	0.932
Dab2	Gipc1	MGP_CAROLIEiJ_P0037758	MGP_CAROLIEiJ_P0085154	Disabled homolog 2.	PDZ domain-containing protein GIPC1.	0.504
Dab2	Myh6	MGP_CAROLIEiJ_P0037758	MGP_CAROLIEiJ_P0036744	Disabled homolog 2.	Myosin heavy chain 6/7.	0.565
Dab2	Myh9	MGP_CAROLIEiJ_P0037758	MGP_CAROLIEiJ_P0038799	Disabled homolog 2.	Myosin heavy chain 9/10/11/14.	0.443
Dab2	Myo6	MGP_CAROLIEiJ_P0037758	MGP_CAROLIEiJ_P0088860	Disabled homolog 2.	Unconventional myosin-VI.	0.992
Dynll2	Bmf	MGP_CAROLIEiJ_P0029106	MGP_CAROLIEiJ_P0053744	Dynein light chain 2, cytoplasmic.	Bcl-2-modifying factor.	0.932
Dynll2	Myl6	MGP_CAROLIEiJ_P0029106	MGP_CAROLIEiJ_P0025162	Dynein light chain 2, cytoplasmic.	Myosin light polypeptide 6 isoform X1.	0.880
Dynll2	Myl6b	MGP_CAROLIEiJ_P0029106	MGP_CAROLIEiJ_P0025163	Dynein light chain 2, cytoplasmic.	Myosin light chain 6B.	0.869
Dynll2	Myo18b	MGP_CAROLIEiJ_P0029106	MGP_CAROLIEiJ_P0069858	Dynein light chain 2, cytoplasmic.	Unconventional myosin-XVIIIb.	0.775
Dynll2	Myo5a	MGP_CAROLIEiJ_P0029106	MGP_CAROLIEiJ_P0088710	Dynein light chain 2, cytoplasmic.	Unconventional myosin-Va.	0.757
Dynll2	Myo7a	MGP_CAROLIEiJ_P0029106	MGP_CAROLIEiJ_P0080763	Dynein light chain 2, cytoplasmic.	Unconventional myosin-VIIa isoform X1.	0.763
Gipc1	Dab2	MGP_CAROLIEiJ_P0085154	MGP_CAROLIEiJ_P0037758	PDZ domain-containing protein GIPC1.	Disabled homolog 2.	0.504
Gipc1	Myo6	MGP_CAROLIEiJ_P0085154	MGP_CAROLIEiJ_P0088860	PDZ domain-containing protein GIPC1.	Unconventional myosin-VI.	0.945
Limch1	MGP_CAROLIEiJ_P0027339	MGP_CAROLIEiJ_P0068425	MGP_CAROLIEiJ_P0027339	LIM and calponin homology domains-containing protein 1 isoform X1.	annotation not available	0.549
Limch1	Myh10	MGP_CAROLIEiJ_P0068425	MGP_CAROLIEiJ_P0027403	LIM and calponin homology domains-containing protein 1 isoform X1.	Myosin heavy chain 9/10/11/14.	0.564
Limch1	Myh11	MGP_CAROLIEiJ_P0068425	MGP_CAROLIEiJ_P0040478	LIM and calponin homology domains-containing protein 1 isoform X1.	Myosin heavy chain 9/10/11/14.	0.562
Limch1	Myh14	MGP_CAROLIEiJ_P0068425	MGP_CAROLIEiJ_P0079339	LIM and calponin homology domains-containing protein 1 isoform X1.	Myosin heavy chain 9/10/11/14.	0.604
Limch1	Myh14-2	MGP_CAROLIEiJ_P0068425	MGP_CAROLIEiJ_P0079340	LIM and calponin homology domains-containing protein 1 isoform X1.	Myosin heavy chain 14.	0.432
Limch1	Myh2	MGP_CAROLIEiJ_P0068425	MGP_CAROLIEiJ_P0027335	LIM and calponin homology domains-containing protein 1 isoform X1.	Myosin, heavy polypeptide 2, skeletal muscle, adult.	0.549
Limch1	Myh6	MGP_CAROLIEiJ_P0068425	MGP_CAROLIEiJ_P0036744	LIM and calponin homology domains-containing protein 1 isoform X1.	Myosin heavy chain 6/7.	0.549