(4 nodes) Hsp90 protein network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Trap1	Heat shock protein 75 kDa, mitochondrial. (706 aa)
	Hsp90aa1	Heat shock protein HSP 90-alpha. (641 aa)
	Hsp90b1	Heat shock protein 90kDa beta. (803 aa)
	Hsp90ab1	Heat shock protein HSP 90-beta. (724 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hsp90aa1	Hsp90ab1	MGP_CAROLIEiJ_P0033364	MGP_CAROLIEiJ_P0044878	Heat shock protein HSP 90-alpha.	Heat shock protein HSP 90-beta.	0.901
Hsp90aa1	Hsp90b1	MGP_CAROLIEiJ_P0033364	MGP_CAROLIEiJ_P0024362	Heat shock protein HSP 90-alpha.	Heat shock protein 90kDa beta.	0.934
Hsp90ab1	Hsp90aa1	MGP_CAROLIEiJ_P0044878	MGP_CAROLIEiJ_P0033364	Heat shock protein HSP 90-beta.	Heat shock protein HSP 90-alpha.	0.901
Hsp90ab1	Hsp90b1	MGP_CAROLIEiJ_P0044878	MGP_CAROLIEiJ_P0024362	Heat shock protein HSP 90-beta.	Heat shock protein 90kDa beta.	0.933
Hsp90b1	Hsp90aa1	MGP_CAROLIEiJ_P0024362	MGP_CAROLIEiJ_P0033364	Heat shock protein 90kDa beta.	Heat shock protein HSP 90-alpha.	0.934
Hsp90b1	Hsp90ab1	MGP_CAROLIEiJ_P0024362	MGP_CAROLIEiJ_P0044878	Heat shock protein 90kDa beta.	Heat shock protein HSP 90-beta.	0.933