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H2ac4 H2ac4 Hist1h2ap Hist1h2ap H2ac11 H2ac11 H4c1 H4c1 H4c2 H4c2 H4c4 H4c4 H2ac8 H2ac8 H4c6 H4c6 H4c8 H4c8 Hist1h4n Hist1h4n H2ac6 H2ac6 H2bc18 H2bc18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2ac4Histone H2A type 1-B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (130 aa)
Hist1h2apHistone cluster 1, H2ap. (130 aa)
H2ac11H2A clustered histone 11. (130 aa)
H4c1H4 clustered histone 1. (103 aa)
H4c2H4 clustered histone 2. (103 aa)
H4c4H4 clustered histone 4. (103 aa)
H2ac8H2A clustered histone 8. (130 aa)
H4c6H4 clustered histone 6. (103 aa)
H4c8H4 clustered histone 8. (103 aa)
Hist1h4nHistone cluster 1, H4n. (103 aa)
H2ac6H2A clustered histone 6. (130 aa)
H2bc18Histone H2B type 2-B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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