STRINGSTRING
Pinlyp Pinlyp Ly6g6e Ly6g6e Agr2 Agr2 Ly6f Ly6f Ly6i Ly6i Lynx1 Lynx1 Lypd2 Lypd2 Psca Psca Sit1 Sit1 Lypd5 Lypd5 Dpep3 Dpep3 Pate6 Pate6 Ly6g5c Ly6g5c Ly6d Ly6d Pate12 Pate12 Agr3 Agr3 Pate5 Pate5 Ly6g5b Ly6g5b Ly6k Ly6k Lypd10 Lypd10 Ly6e Ly6e Tacstd2 Tacstd2 Lypd6 Lypd6 Tex101 Tex101 Lypd3 Lypd3 Lypd11 Lypd11 Pate14 Pate14 Spaca4 Spaca4 Gml2 Gml2 Gml Gml Pate9 Pate9 Pate2 Pate2 Ly6h Ly6h Lypd1 Lypd1 Pate8 Pate8 Pate11 Pate11 Pate7 Pate7 Pate1 Pate1 Pate10 Pate10 Ly6g6c Ly6g6c Ly6l Ly6l Pate13 Pate13 Pate3 Pate3 Ly6a Ly6a Ly6g6g Ly6g6g
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PinlypPhospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein. (212 aa)
Ly6g6eLymphocyte antigen 6G6e; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro potentiates alpha-3:beta-4- containing nAChRs maximum response by increasing peak current and slowing down receptor desensitization; the activity is dependent on its cell surface localization. (134 aa)
Agr2Anterior gradient protein 2 homolog; Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth (By similarity). Promotes cell adhesion (By similarity); Belongs to the AGR family. (175 aa)
Ly6fLymphocyte antigen 6F. (134 aa)
Ly6iLymphocyte antigen 6I. (134 aa)
Lynx1Ly-6/neurotoxin-like protein 1; Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). The proposed role as modulator of nAChR activity seems to be dependent on the nAChR subtype and stoichiometry, and to involve an effect on nAChR trafficking and its cell surface expression, and on single channel properties of the nAChR inserted in the plasma membrane.Modulates functional properties of nicotinic acetylcholine receptors (nAChRs) to prevent excessive excitation, and hence neurodegeneration. Enhances desensitization by increasing both the rate and ex [...] (116 aa)
Lypd2Ly6/PLAUR domain-containing protein 2. (127 aa)
PscaProstate stem cell antigen; May be involved in the regulation of cell proliferation. (123 aa)
Sit1Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells. (180 aa)
Lypd5Ly6/PLAUR domain-containing protein 5. (256 aa)
Dpep3Dipeptidase 3; Probable metalloprotease which hydrolyzes cystinyl-bis- glycine. May be involved in meiosis. (493 aa)
Pate6Prostate and testis-expressed 6. (106 aa)
Ly6g5cLymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation. (149 aa)
Ly6dLymphocyte antigen 6D; May act as a specification marker at earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification. (127 aa)
Pate12Prostate and testis-expressed 12. (99 aa)
Agr3Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells. (165 aa)
Pate5Prostate and testis-expressed 5. (117 aa)
Ly6g5bLymphocyte antigen 6 complex locus protein G5b. (194 aa)
Ly6kLymphocyte antigen 6K; Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida. May play a role in cell growth (By similarity). (154 aa)
Lypd10Ly6/PLAUR domain-containing 10. (246 aa)
Ly6eLymphocyte antigen 6E; Involved in T-cell development. Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. (136 aa)
Tacstd2Tumor-associated calcium signal transducer 2; May function as a growth factor receptor. (317 aa)
Lypd6Ly6/PLAUR domain-containing protein 6; Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Enhances nicotine-induced Ca(2+) influx through nAChRs. Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity). (171 aa)
Tex101Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct probably through molecule adhesion ADAM3. May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity). (250 aa)
Lypd3Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in tumor progression (By similarity). (363 aa)
Lypd11Ly6/PLAUR domain-containing 11. (196 aa)
Pate14Secreted seminal-vesicle Ly-6 protein 1. (99 aa)
Spaca4Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Belongs to the SPACA4/bouncer family. (127 aa)
Gml2Glycosylphosphatidylinositol-anchored molecule-like 2. (176 aa)
GmlGlycosylphosphatidylinositol-anchored molecule-like. (176 aa)
Pate9Prostate and testis-expressed 9. (101 aa)
Pate2Prostate and testis expressed protein 2. (111 aa)
Ly6hLymphocyte antigen 6H; Believed to act as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4- containing nAChRs maximum response. In vitro inhibits alpha-3:beta-4- containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons (By similarity). (160 aa)
Lypd1Ly6/PLAUR domain-containing protein 1; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2- containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety. (141 aa)
Pate8Secreted TFP/Ly-6/uPAR protein PATE-G. (109 aa)
Pate11Secreted TFP/Ly-6/uPAR protein PATE-P. (99 aa)
Pate7Prostate and testis-expressed 7. (109 aa)
Pate1Prostate and testis-expressed 1. (125 aa)
Pate10Secreted TFP/Ly-6/uPAR protein PATE-N. (116 aa)
Ly6g6cLymphocyte antigen 6 complex locus protein G6c. (126 aa)
Ly6lLymphocyte antigen 6L. (140 aa)
Pate13Prostate and testis-expressed 13. (137 aa)
Pate3Prostate and testis expressed protein 3. (98 aa)
Ly6aLymphocyte antigen 6A-2/6E-1; T-cell activation. (134 aa)
Ly6g6gLymphocyte antigen 6 complex, locus G6G. (115 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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