STRINGSTRING
Pinlyp Pinlyp Lypd10 Lypd10 Lypd9 Lypd9 Cd177 Cd177 Tex101 Tex101 Lypd4 Lypd4 Lypd3 Lypd3 Lypd11 Lypd11 Spaca4 Spaca4 2210407C18Rik 2210407C18Rik Lypd8 Lypd8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PinlypPhospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein. (212 aa)
Lypd10Ly6/PLAUR domain-containing 10. (246 aa)
Lypd9LY6/PLAUR domain-containing 9. (145 aa)
Cd177CD177 antigen; In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (By similarity). In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (By similarity). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (By similarity). However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo. [...] (817 aa)
Tex101Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct probably through molecule adhesion ADAM3. May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity). (250 aa)
Lypd4Ly6/PLAUR domain-containing protein 4. (246 aa)
Lypd3Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in tumor progression (By similarity). (363 aa)
Lypd11Ly6/PLAUR domain-containing 11. (196 aa)
Spaca4Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Belongs to the SPACA4/bouncer family. (127 aa)
2210407C18RikRIKEN cDNA 2210407C18 gene. (220 aa)
Lypd8Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis; Belongs to the CNF-like-inhibitor family. (255 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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