STRINGSTRING
Rps2 Rps2 Rps11 Rps11 Rpl19 Rpl19 Myc Myc Trmu Trmu Rpl24 Rpl24 Mycl Mycl Rpl6 Rpl6 Mto1 Mto1 Tfb1m Tfb1m Abca3 Abca3 Mycn Mycn Rps25 Rps25 Rps17 Rps17 Rpl31 Rpl31 Rps6 Rps6 Rpl27 Rpl27 Rps16 Rps16 Rps19 Rps19 Rpl9 Rpl9 Gapdh Gapdh Rps20 Rps20 Rpl26 Rpl26 Gm3839 Gm3839 Rpl18 Rpl18 Gm10358 Gm10358 Rpl8 Rpl8 Rps14 Rps14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rps240S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (293 aa)
Rps1140S ribosomal protein S11. (158 aa)
Rpl1960S ribosomal protein L19. (196 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. (454 aa)
TrmuMitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. (417 aa)
Rpl2460S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family. (157 aa)
MyclProtein L-Myc. (368 aa)
Rpl660S ribosomal protein L6; Component of the large ribosomal subunit. (296 aa)
Mto1Protein MTO1 homolog, mitochondrial; Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. Belongs to the MnmG family. (669 aa)
Tfb1mDimethyladenosine transferase 1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily. (345 aa)
Abca3ATP-binding cassette sub-family A member 3; Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol. (1704 aa)
MycnN-myc proto-oncogene protein; Positively regulates the transcription of MYCNOS in neuroblastoma cells. (462 aa)
Rps2540S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (125 aa)
Rps1740S ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family. (135 aa)
Rpl3160S ribosomal protein L31; Belongs to the eukaryotic ribosomal protein eL31 family. (125 aa)
Rps640S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. (249 aa)
Rpl2760S ribosomal protein L27; Component of the large ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity). (136 aa)
Rps1640S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
Rps1940S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family. (145 aa)
Rpl960S ribosomal protein L9; Belongs to the universal ribosomal protein uL6 family. (192 aa)
GapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (359 aa)
Rps2040S ribosomal protein S20. (119 aa)
Rpl2660S ribosomal protein L26; Component of the large ribosomal subunit. (145 aa)
Gm3839Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
Rpl1860S ribosomal protein L18; Component of the large ribosomal subunit. (188 aa)
Gm10358Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
Rpl860S ribosomal protein L8; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL2 family. (257 aa)
Rps1440S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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