STRINGSTRING
Rps25 Rps25 Rpl15 Rpl15 Rpl10a Rpl10a Rpl28 Rpl28 Rpl6 Rpl6 Rpl22 Rpl22 Trp53 Trp53 Rps5 Rps5 Rps16 Rps16 Rpl38 Rpl38 Rps6 Rps6 Rps18 Rps18 Ess2 Ess2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rps2540S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (125 aa)
Rpl1560S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
Rpl10a60S ribosomal protein L10a; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL1 family. (217 aa)
Rpl2860S ribosomal protein L28; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL28 family. (137 aa)
Rpl660S ribosomal protein L6; Component of the large ribosomal subunit. (296 aa)
Rpl2260S ribosomal protein L22. (128 aa)
Trp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (390 aa)
Rps540S ribosomal protein S5, N-terminally processed; Belongs to the universal ribosomal protein uS7 family. (204 aa)
Rps1640S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
Rpl3860S ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
Rps640S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. (249 aa)
Rps1840S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA. (152 aa)
Ess2Splicing factor ESS-2 homolog; May be involved in pre-mRNA splicing. (480 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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