STRINGSTRING
Irs4 Irs4 Eras Eras Stat1 Stat1 Creb1 Creb1 Irs1 Irs1 Cacna1s Cacna1s Adcy10 Adcy10 Akt3 Akt3 Shc2 Shc2 Map2k2 Map2k2 Gna11 Gna11 Igf1 Igf1 Socs2 Socs2 Adcy1 Adcy1 Igfbp3 Igfbp3 Mapk9 Mapk9 Map2k4 Map2k4 Crk Crk Stat5b Stat5b MGP_SPRETEiJ_P0031352 MGP_SPRETEiJ_P0031352 Stat3 Stat3 Gh Gh Prkca Prkca Map2k6 Map2k6 Sstr2 Sstr2 Grb2 Grb2 Socs3 Socs3 Adcy3 Adcy3 Ptrhd1 Ptrhd1 Sstr1 Sstr1 Sos2 Sos2 Fos Fos Akt1 Akt1 Shc3 Shc3 Adcy2 Adcy2 Pik3r1 Pik3r1 Map3k1 Map3k1 Cacna1d Cacna1d Mapk8 Mapk8 Ghr Ghr Adcy8 Adcy8 Ptk2 Ptk2 Sstr3 Sstr3 Atf4 Atf4 Ep300 Ep300 Mapk12 Mapk12 Mapk11 Mapk11 Adcy6 Adcy6 Crebbp Crebbp Adcy9 Adcy9 Socs1 Socs1 Mapk1 Mapk1 Crkl Crkl Sst Sst Adcy5 Adcy5 Gsk3b Gsk3b Pou1f1 Pou1f1 Igfals Igfals Sstr5 Sstr5 Itpr3 Itpr3 Mapk14 Mapk14 Mapk13 Mapk13 Atf6b Atf6b Sos1 Sos1 Plcb3 Plcb3 Gnaq Gnaq Jak2 Jak2 Atf2 Atf2 Creb3l1 Creb3l1 Plcb2 Plcb2 Shc4 Shc4 Plcb1 Plcb1 Plcb4 Plcb4 Ghrh Ghrh Plcg1 Plcg1 Gnas Gnas Ghsr Ghsr Pik3ca Pik3ca Shc1 Shc1 Creb3l4 Creb3l4 Csde1 Csde1 Nras Nras Gnai3 Gnai3 Prkacb Prkacb Creb3 Creb3 MGP_SPRETEiJ_P0066259 MGP_SPRETEiJ_P0066259 Mtor Mtor Pik3cd Pik3cd Gnai1 Gnai1 Mapk10 Mapk10 Irs3 Irs3 Creb3l2 Creb3l2 Creb5 Creb5 Ghrhr Ghrhr Itpr1 Itpr1 Ghrl Ghrl Raf1 Raf1 Cacna1c Cacna1c Kras Kras Itpr2 Itpr2 Prkcg Prkcg Akt2 Akt2 Prkcb Prkcb Mapk3 Mapk3 Hras Hras Irs2 Irs2 Pik3r2 Pik3r2 Prkaca Prkaca Junb Junb Adcy7 Adcy7 Bcar1 Bcar1 Plcg2 Plcg2 Map2k1 Map2k1 Pik3cb Pik3cb Gnai2 Gnai2 Cacna1f Cacna1f
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Irs4Insulin receptor substrate 4. (1217 aa)
ErasES cell-expressed Ras. (227 aa)
Stat1Signal transducer and activator of transcription 1. (755 aa)
Creb1cAMP responsive element binding protein 1. (341 aa)
Irs1Insulin receptor substrate 1. (1230 aa)
Cacna1sCalcium channel, voltage-dependent, L type, alpha 1S subunit. (1852 aa)
Adcy10Adenylate cyclase 10. (1614 aa)
Akt3Thymoma viral proto-oncogene 3. (479 aa)
Shc2SHC (Src homology 2 domain containing) transforming protein 2. (573 aa)
Map2k2Mitogen-activated protein kinase kinase 2. (401 aa)
Gna11Guanine nucleotide binding protein, alpha 11. (359 aa)
Igf1Insulin-like growth factor 1. (165 aa)
Socs2Suppressor of cytokine signaling 2. (198 aa)
Adcy1Adenylate cyclase 1. (1118 aa)
Igfbp3Insulin-like growth factor binding protein 3. (292 aa)
Mapk9Mitogen-activated protein kinase 9. (423 aa)
Map2k4Mitogen-activated protein kinase kinase 4. (397 aa)
CrkV-crk avian sarcoma virus CT10 oncogene homolog. (304 aa)
Stat5bSignal transducer and activator of transcription 5B. (674 aa)
MGP_SPRETEiJ_P0031352annotation not available (678 aa)
Stat3Signal transducer and activator of transcription 3. (770 aa)
GhGrowth hormone. (216 aa)
PrkcaProtein kinase C, alpha. (672 aa)
Map2k6Mitogen-activated protein kinase kinase 6. (334 aa)
Sstr2Somatostatin receptor 2. (369 aa)
Grb2Growth factor receptor bound protein 2. (217 aa)
Socs3Suppressor of cytokine signaling 3. (225 aa)
Adcy3Adenylate cyclase 3. (1145 aa)
Ptrhd1peptidyl-tRNA hydrolase domain containing 1. (140 aa)
Sstr1Somatostatin receptor 1. (391 aa)
Sos2SOS Ras/Rho guanine nucleotide exchange factor 2. (1333 aa)
FosFBJ osteosarcoma oncogene. (380 aa)
Akt1Thymoma viral proto-oncogene 1. (480 aa)
Shc3Src homology 2 domain-containing transforming protein C3. (474 aa)
Adcy2Adenylate cyclase 2. (1095 aa)
Pik3r1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
Map3k1Mitogen-activated protein kinase kinase kinase 1. (1477 aa)
Cacna1dCalcium channel, voltage-dependent, L type, alpha 1D subunit. (2166 aa)
Mapk8Mitogen-activated protein kinase 8. (427 aa)
GhrGrowth hormone receptor. (650 aa)
Adcy8Adenylate cyclase 8. (1249 aa)
Ptk2PTK2 protein tyrosine kinase 2. (1052 aa)
Sstr3Somatostatin receptor 3. (428 aa)
Atf4Activating transcription factor 4. (349 aa)
Ep300E1A binding protein p300. (2415 aa)
Mapk12Mitogen-activated protein kinase 12. (367 aa)
Mapk11Mitogen-activated protein kinase 11. (364 aa)
Adcy6Adenylate cyclase 6. (1168 aa)
CrebbpCREB binding protein. (2442 aa)
Adcy9Adenylate cyclase 9. (1353 aa)
Socs1Suppressor of cytokine signaling 1. (212 aa)
Mapk1Mitogen-activated protein kinase 1. (358 aa)
CrklV-crk avian sarcoma virus CT10 oncogene homolog-like. (303 aa)
SstSomatostatin. (116 aa)
Adcy5Adenylate cyclase 5. (1265 aa)
Gsk3bGlycogen synthase kinase 3 beta. (433 aa)
Pou1f1POU domain, class 1, transcription factor 1. (317 aa)
IgfalsInsulin-like growth factor binding protein, acid labile subunit. (603 aa)
Sstr5Somatostatin receptor 5. (362 aa)
Itpr3Inositol 1,4,5-triphosphate receptor 3. (2670 aa)
Mapk14Mitogen-activated protein kinase 14. (360 aa)
Mapk13Mitogen-activated protein kinase 13. (366 aa)
Atf6bActivating transcription factor 6 beta. (709 aa)
Sos1SOS Ras/Rac guanine nucleotide exchange factor 1. (1319 aa)
Plcb3Phospholipase C, beta 3. (1234 aa)
GnaqGuanine nucleotide binding protein, alpha q polypeptide. (359 aa)
Jak2Janus kinase 2. (1132 aa)
Atf2Activating transcription factor 2. (487 aa)
Creb3l1cAMP responsive element binding protein 3-like 1. (520 aa)
Plcb2Phospholipase C, beta 2. (1181 aa)
Shc4SHC (Src homology 2 domain containing) family, member 4. (626 aa)
Plcb1Phospholipase C, beta 1. (1216 aa)
Plcb4Phospholipase C, beta 4. (1239 aa)
GhrhGrowth hormone releasing hormone. (103 aa)
Plcg1Phospholipase C, gamma 1. (1302 aa)
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus. (1133 aa)
GhsrGrowth hormone secretagogue receptor. (364 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha. (1068 aa)
Shc1Src homology 2 domain-containing transforming protein C1. (579 aa)
Creb3l4cAMP responsive element binding protein 3-like 4. (370 aa)
Csde1Cold shock domain containing E1, RNA binding. (798 aa)
NrasNeuroblastoma ras oncogene. (189 aa)
Gnai3Guanine nucleotide binding protein (G protein), alpha inhibiting 3. (354 aa)
PrkacbProtein kinase, cAMP dependent, catalytic, beta. (398 aa)
Creb3cAMP responsive element binding protein 3. (379 aa)
MGP_SPRETEiJ_P0066259annotation not available (461 aa)
MtorMechanistic target of rapamycin kinase. (2549 aa)
Pik3cdPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta. (1047 aa)
Gnai1Guanine nucleotide binding protein (G protein), alpha inhibiting 1. (354 aa)
Mapk10Mitogen-activated protein kinase 10. (494 aa)
Irs3Insulin receptor substrate 3. (495 aa)
Creb3l2cAMP responsive element binding protein 3-like 2. (521 aa)
Creb5cAMP responsive element binding protein 5. (519 aa)
GhrhrGrowth hormone releasing hormone receptor. (423 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor 1. (2749 aa)
GhrlGhrelin. (117 aa)
Raf1V-raf-leukemia viral oncogene 1. (648 aa)
Cacna1cCalcium channel, voltage-dependent, L type, alpha 1C subunit. (2222 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (189 aa)
Itpr2Inositol 1,4,5-triphosphate receptor 2. (2701 aa)
PrkcgProtein kinase C, gamma. (697 aa)
Akt2Thymoma viral proto-oncogene 2. (481 aa)
PrkcbProtein kinase C, beta. (673 aa)
Mapk3Mitogen-activated protein kinase 3. (380 aa)
HrasHarvey rat sarcoma virus oncogene. (189 aa)
Irs2Insulin receptor substrate 2. (1320 aa)
Pik3r2Phosphoinositide-3-kinase regulatory subunit 2. (722 aa)
PrkacaProtein kinase, cAMP dependent, catalytic, alpha. (351 aa)
JunbJun B proto-oncogene. (344 aa)
Adcy7Adenylate cyclase 7. (1104 aa)
Bcar1Breast cancer anti-estrogen resistance 1. (874 aa)
Plcg2Phospholipase C, gamma 2. (1265 aa)
Map2k1Mitogen-activated protein kinase kinase 1. (393 aa)
Pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta. (1064 aa)
Gnai2Guanine nucleotide binding protein (G protein), alpha inhibiting 2. (355 aa)
Cacna1fCalcium channel, voltage-dependent, alpha 1F subunit. (1982 aa)
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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