(113 nodes) Pancreatic secretion network (Mus spretus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1. (994 aa)
	Cpa6	Carboxypeptidase A6. (438 aa)
	Sctr	Secretin receptor. (464 aa)
	Atp2b4	ATPase, Ca++ transporting, plasma membrane 4. (1205 aa)
	Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide. (304 aa)
	Atp1a4	ATPase, Na+/K+ transporting, alpha 4 polypeptide. (1032 aa)
	Atp1a2	ATPase, Na+/K+ transporting, alpha 2 polypeptide. (1020 aa)
	Pla2g12b	Phospholipase A2, group XIIB. (195 aa)
	Atp2b1	ATPase, Ca++ transporting, plasma membrane 1. (1220 aa)
	Rap1b	RAS related protein 1b. (184 aa)
	Pla2g3	Phospholipase A2, group III. (502 aa)
	Adcy1	Adenylate cyclase 1. (1118 aa)
	Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide. (290 aa)
	Atp2a3	ATPase, Ca++ transporting, ubiquitous. (1038 aa)
	Prkca	Protein kinase C, alpha. (672 aa)
	Adcy3	Adenylate cyclase 3. (1145 aa)
	Ptrhd1	peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	Slc26a3	Solute carrier family 26, member 3. (757 aa)
	Chrm3	Cholinergic receptor, muscarinic 3, cardiac. (589 aa)
	Ryr2	Ryanodine receptor 2, cardiac. (4969 aa)
	Adcy2	Adenylate cyclase 2. (1095 aa)
	Kcnma1	Potassium large conductance calcium-activated channel, subfamily M, alpha member 1. (1239 aa)
	Cpb2	Carboxypeptidase B2 (plasma). (422 aa)
	Adcy8	Adenylate cyclase 8. (1249 aa)
	Adcy6	Adenylate cyclase 6. (1168 aa)
	Cela1	Chymotrypsin-like elastase family, member 1. (266 aa)
	Adcy9	Adenylate cyclase 9. (1353 aa)
	Pla2g10	Phospholipase A2, group X. (151 aa)
	Adcy5	Adenylate cyclase 5. (1265 aa)
	Itpr3	Inositol 1,4,5-triphosphate receptor 3. (2670 aa)
	Slc12a2	Solute carrier family 12, member 2. (1204 aa)
	Rab27b	RAB27B, member RAS oncogene family. (218 aa)
	Plcb3	Phospholipase C, beta 3. (1234 aa)
	Gnaq	Guanine nucleotide binding protein, alpha q polypeptide. (359 aa)
	Pnlip	Pancreatic lipase. (465 aa)
	Pnliprp1	Pancreatic lipase related protein 1. (473 aa)
	Pnliprp2	Pancreatic lipase-related protein 2. (482 aa)
	Cel	Carboxyl ester lipase. (599 aa)
	Plcb2	Phospholipase C, beta 2. (1181 aa)
	Plcb1	Phospholipase C, beta 1. (1216 aa)
	Plcb4	Phospholipase C, beta 4. (1239 aa)
	Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus. (1133 aa)
	Car2	Carbonic anhydrase 2. (260 aa)
	MGP_SPRETEiJ_P0059296	Carboxypeptidase B1 (tissue). (415 aa)
	Cpa3	Carboxypeptidase A3, mast cell. (417 aa)
	Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide. (1023 aa)
	Rhoc	Ras homolog family member C. (193 aa)
	Rap1a	RAS-related protein 1a. (184 aa)
	MGP_SPRETEiJ_P0062450	annotation not available (241 aa)
	MGP_SPRETEiJ_P0062451	annotation not available (418 aa)
	Amy1	Amylase 1, salivary. (511 aa)
	Pla2g12a	Phospholipase A2, group XIIA. (192 aa)
	MGP_SPRETEiJ_P0063298	annotation not available (221 aa)
	Clca3b	Chloride channel accessory 3B. (942 aa)
	Clca1	Chloride channel accessory 1. (913 aa)
	Clca2	Chloride channel accessory 2. (942 aa)
	Slc9a1	Solute carrier family 9 (sodium/hydrogen exchanger), member 1. (820 aa)
	MGP_SPRETEiJ_P0067847	annotation not available (283 aa)
	MGP_SPRETEiJ_P0067848	annotation not available (269 aa)
	Pla2g2c	Phospholipase A2, group IIC. (150 aa)
	Pla2g2f	Phospholipase A2, group IIF. (210 aa)
	Pla2g2d	Phospholipase A2, group IID. (144 aa)
	Pla2g5	Phospholipase A2, group V. (137 aa)
	Pla2g2e	Phospholipase A2, group IIE. (142 aa)
	Cela2a	Chymotrypsin-like elastase family, member 2A. (271 aa)
	Ctrc	Chymotrypsin C (caldecrin). (264 aa)
	Slc4a2	Solute carrier family 4 (anion exchanger), member 2. (1237 aa)
	Bst1	Bone marrow stromal cell antigen 1. (311 aa)
	Cd38	CD38 antigen. (304 aa)
	Cckar	Cholecystokinin A receptor. (436 aa)
	Slc4a4	Solute carrier family 4 (anion exchanger), member 4. (1094 aa)
	Pla2g1b	Phospholipase A2, group IB, pancreas. (146 aa)
	Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2. (1044 aa)
	Rac1	Rac family small GTPase 1. (192 aa)
	Cftr	Cystic fibrosis transmembrane conductance regulator. (1445 aa)
	Cpa2	Carboxypeptidase A2, pancreatic. (417 aa)
	Cpa4	Carboxypeptidase A4. (420 aa)
	Cpa1	Carboxypeptidase A1, pancreatic. (419 aa)
	Prss37	Protease, serine 37. (237 aa)
	MGP_SPRETEiJ_P0076292	annotation not available (154 aa)
	MGP_SPRETEiJ_P0076293	annotation not available (247 aa)
	MGP_SPRETEiJ_P0076294	annotation not available (247 aa)
	2210010C04Rik	RIKEN cDNA 2210010C04 gene. (247 aa)
	MGP_SPRETEiJ_P0076298	annotation not available (246 aa)
	Try10	Trypsin 10. (246 aa)
	MGP_SPRETEiJ_P0076300	annotation not available (224 aa)
	MGP_SPRETEiJ_P0076301	annotation not available (224 aa)
	MGP_SPRETEiJ_P0076302	annotation not available (176 aa)
	MGP_SPRETEiJ_P0076303	annotation not available (176 aa)
	Prss2	Protease, serine 2. (246 aa)
	4930544G11Rik	RIKEN cDNA 4930544G11 gene. (193 aa)
	Itpr1	Inositol 1,4,5-trisphosphate receptor 1. (2749 aa)
	Atp2b2	ATPase, Ca++ transporting, plasma membrane 2. (1243 aa)
	Itpr2	Inositol 1,4,5-triphosphate receptor 2. (2701 aa)
	Prkcg	Protein kinase C, gamma. (697 aa)
	Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide. (1054 aa)
	Ovch2	Ovochymase 2. (609 aa)
	Prkcb	Protein kinase C, beta. (673 aa)
	Sct	Secretin. (139 aa)
	Kcnq1	Potassium voltage-gated channel, subfamily Q, member 1. (668 aa)
	Tpcn2	Two pore segment channel 2. (731 aa)
	Rab8a	RAB8A, member RAS oncogene family. (207 aa)
	Adcy7	Adenylate cyclase 7. (1104 aa)
	Ctrl	Chymotrypsin-like. (264 aa)
	Ctrb1	Chymotrypsinogen B1. (263 aa)
	Rab3d	RAB3D, member RAS oncogene family. (219 aa)
	Rab11a	RAB11A, member RAS oncogene family. (216 aa)
	Rab27a	RAB27A, member RAS oncogene family. (221 aa)
	Trpc1	Transient receptor potential cation channel, subfamily C, member 1. (809 aa)
	Atp1b3	ATPase, Na+/K+ transporting, beta 3 polypeptide. (278 aa)
	Cck	Cholecystokinin. (115 aa)
	Atp1b4	ATPase, (Na+)/K+ transporting, beta 4 polypeptide. (356 aa)
	Atp2b3	ATPase, Ca++ transporting, plasma membrane 3. (1220 aa)

Your Current Organism:

Mus spretus

NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
2210010C04Rik	Cel	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0052595	RIKEN cDNA 2210010C04 gene.	Carboxyl ester lipase.	0.982
2210010C04Rik	Cela1	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0041700	RIKEN cDNA 2210010C04 gene.	Chymotrypsin-like elastase family, member 1.	0.438
2210010C04Rik	Cela2a	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0068197	RIKEN cDNA 2210010C04 gene.	Chymotrypsin-like elastase family, member 2A.	0.919
2210010C04Rik	Cftr	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0075570	RIKEN cDNA 2210010C04 gene.	Cystic fibrosis transmembrane conductance regulator.	0.453
2210010C04Rik	Cpa1	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0075915	RIKEN cDNA 2210010C04 gene.	Carboxypeptidase A1, pancreatic.	0.991
2210010C04Rik	Cpa2	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0075902	RIKEN cDNA 2210010C04 gene.	Carboxypeptidase A2, pancreatic.	0.709
2210010C04Rik	Ctrb1	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0089599	RIKEN cDNA 2210010C04 gene.	Chymotrypsinogen B1.	0.992
2210010C04Rik	Ctrc	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0068202	RIKEN cDNA 2210010C04 gene.	Chymotrypsin C (caldecrin).	0.656
2210010C04Rik	Ctrl	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0089356	RIKEN cDNA 2210010C04 gene.	Chymotrypsin-like.	0.988
2210010C04Rik	MGP_SPRETEiJ_P0059296	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0059296	RIKEN cDNA 2210010C04 gene.	Carboxypeptidase B1 (tissue).	0.987
2210010C04Rik	MGP_SPRETEiJ_P0067847	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0067847	RIKEN cDNA 2210010C04 gene.	annotation not available	0.984
2210010C04Rik	MGP_SPRETEiJ_P0067848	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0067848	RIKEN cDNA 2210010C04 gene.	annotation not available	0.984
2210010C04Rik	Pnlip	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0051279	RIKEN cDNA 2210010C04 gene.	Pancreatic lipase.	0.940
2210010C04Rik	Pnliprp1	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0051280	RIKEN cDNA 2210010C04 gene.	Pancreatic lipase related protein 1.	0.762
2210010C04Rik	Pnliprp2	MGP_SPRETEiJ_P0076295	MGP_SPRETEiJ_P0051281	RIKEN cDNA 2210010C04 gene.	Pancreatic lipase-related protein 2.	0.451
4930544G11Rik	Rac1	MGP_SPRETEiJ_P0077038	MGP_SPRETEiJ_P0074828	RIKEN cDNA 4930544G11 gene.	Rac family small GTPase 1.	0.752
4930544G11Rik	Rap1a	MGP_SPRETEiJ_P0077038	MGP_SPRETEiJ_P0062128	RIKEN cDNA 4930544G11 gene.	RAS-related protein 1a.	0.836
4930544G11Rik	Rap1b	MGP_SPRETEiJ_P0077038	MGP_SPRETEiJ_P0026099	RIKEN cDNA 4930544G11 gene.	RAS related protein 1b.	0.863
Adcy1	Adcy2	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0036491	Adenylate cyclase 1.	Adenylate cyclase 2.	0.568
Adcy1	Adcy5	MGP_SPRETEiJ_P0026987	MGP_SPRETEiJ_P0043297	Adenylate cyclase 1.	Adenylate cyclase 5.	0.562