| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A3galt2 | B3galt1 | ENSRNOP00000007851 | ENSRNOP00000010018 | Alpha-1,3-galactosyltransferase 2; Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Synthesis of iGb3 is the initial step in the formation of the isoglobo- series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids. Can glycosylate only lipids and not proteins and i [...] | Hexosyltransferase. | 0.558 |
| A3galt2 | B4galnt1 | ENSRNOP00000007851 | ENSRNOP00000048586 | Alpha-1,3-galactosyltransferase 2; Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Synthesis of iGb3 is the initial step in the formation of the isoglobo- series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids. Can glycosylate only lipids and not proteins and i [...] | Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and asialo-GM2; Belongs to the glycosyltransferase 2 family. | 0.570 |
| Abo | Abo2 | ENSRNOP00000039997 | ENSRNOP00000057988 | Histo-blood group ABO system transferase 2; Posseses strong B transferase activity and a weak A transferase activity; Belongs to the glycosyltransferase 6 family. | Histo-blood group ABO system transferase 2. | 0.900 |
| Abo | Abo3 | ENSRNOP00000039997 | ENSRNOP00000006553 | Histo-blood group ABO system transferase 2; Posseses strong B transferase activity and a weak A transferase activity; Belongs to the glycosyltransferase 6 family. | Histo-blood group ABO system transferase 1; Posseses strong A transferase activity and a weak B transferase activity. | 0.902 |
| Abo | St3gal2 | ENSRNOP00000039997 | ENSRNOP00000024248 | Histo-blood group ABO system transferase 2; Posseses strong B transferase activity and a weak A transferase activity; Belongs to the glycosyltransferase 6 family. | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. | 0.439 |
| Abo | St3gal4 | ENSRNOP00000039997 | ENSRNOP00000013243 | Histo-blood group ABO system transferase 2; Posseses strong B transferase activity and a weak A transferase activity; Belongs to the glycosyltransferase 6 family. | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4- GlcNAc-, and NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant. | 0.415 |
| Abo2 | Abo | ENSRNOP00000057988 | ENSRNOP00000039997 | Histo-blood group ABO system transferase 2. | Histo-blood group ABO system transferase 2; Posseses strong B transferase activity and a weak A transferase activity; Belongs to the glycosyltransferase 6 family. | 0.900 |
| Abo2 | Abo3 | ENSRNOP00000057988 | ENSRNOP00000006553 | Histo-blood group ABO system transferase 2. | Histo-blood group ABO system transferase 1; Posseses strong A transferase activity and a weak B transferase activity. | 0.902 |
| Abo3 | Abo | ENSRNOP00000006553 | ENSRNOP00000039997 | Histo-blood group ABO system transferase 1; Posseses strong A transferase activity and a weak B transferase activity. | Histo-blood group ABO system transferase 2; Posseses strong B transferase activity and a weak A transferase activity; Belongs to the glycosyltransferase 6 family. | 0.902 |
| Abo3 | Abo2 | ENSRNOP00000006553 | ENSRNOP00000057988 | Histo-blood group ABO system transferase 1; Posseses strong A transferase activity and a weak B transferase activity. | Histo-blood group ABO system transferase 2. | 0.902 |
| B3galt1 | A3galt2 | ENSRNOP00000010018 | ENSRNOP00000007851 | Hexosyltransferase. | Alpha-1,3-galactosyltransferase 2; Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Synthesis of iGb3 is the initial step in the formation of the isoglobo- series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids. Can glycosylate only lipids and not proteins and i [...] | 0.558 |
| B3galt1 | St3gal4 | ENSRNOP00000010018 | ENSRNOP00000013243 | Hexosyltransferase. | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4- GlcNAc-, and NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant. | 0.928 |
| B4galnt1 | A3galt2 | ENSRNOP00000048586 | ENSRNOP00000007851 | Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and asialo-GM2; Belongs to the glycosyltransferase 2 family. | Alpha-1,3-galactosyltransferase 2; Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Synthesis of iGb3 is the initial step in the formation of the isoglobo- series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids. Can glycosylate only lipids and not proteins and i [...] | 0.570 |
| B4galnt1 | Gba2 | ENSRNOP00000048586 | ENSRNOP00000022002 | Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and asialo-GM2; Belongs to the glycosyltransferase 2 family. | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide (By similarity). Glucosylceramides are membrane glycosphingolipids that have a wide intracellular distribution. They are the main precursors of more complex glycosphingolipids that play a role in cellular growth, differentiation, adhesion, signaling, cytoskeletal dynamics and membrane properties. Also involved in the transglucosylation of cholesterol, transferring glucose from glucosylceramides, thereby modifying its water solubility [...] | 0.421 |
| B4galnt1 | St3gal2 | ENSRNOP00000048586 | ENSRNOP00000024248 | Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and asialo-GM2; Belongs to the glycosyltransferase 2 family. | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. | 0.705 |
| Gba | Gba2 | ENSRNOP00000063935 | ENSRNOP00000022002 | Glucosylceramidase. | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide (By similarity). Glucosylceramides are membrane glycosphingolipids that have a wide intracellular distribution. They are the main precursors of more complex glycosphingolipids that play a role in cellular growth, differentiation, adhesion, signaling, cytoskeletal dynamics and membrane properties. Also involved in the transglucosylation of cholesterol, transferring glucose from glucosylceramides, thereby modifying its water solubility [...] | 0.974 |
| Gba2 | B4galnt1 | ENSRNOP00000022002 | ENSRNOP00000048586 | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide (By similarity). Glucosylceramides are membrane glycosphingolipids that have a wide intracellular distribution. They are the main precursors of more complex glycosphingolipids that play a role in cellular growth, differentiation, adhesion, signaling, cytoskeletal dynamics and membrane properties. Also involved in the transglucosylation of cholesterol, transferring glucose from glucosylceramides, thereby modifying its water solubility [...] | Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and asialo-GM2; Belongs to the glycosyltransferase 2 family. | 0.421 |
| Gba2 | Gba | ENSRNOP00000022002 | ENSRNOP00000063935 | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide (By similarity). Glucosylceramides are membrane glycosphingolipids that have a wide intracellular distribution. They are the main precursors of more complex glycosphingolipids that play a role in cellular growth, differentiation, adhesion, signaling, cytoskeletal dynamics and membrane properties. Also involved in the transglucosylation of cholesterol, transferring glucose from glucosylceramides, thereby modifying its water solubility [...] | Glucosylceramidase. | 0.974 |
| St3gal2 | Abo | ENSRNOP00000024248 | ENSRNOP00000039997 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. | Histo-blood group ABO system transferase 2; Posseses strong B transferase activity and a weak A transferase activity; Belongs to the glycosyltransferase 6 family. | 0.439 |
| St3gal2 | B4galnt1 | ENSRNOP00000024248 | ENSRNOP00000048586 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. | Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and asialo-GM2; Belongs to the glycosyltransferase 2 family. | 0.705 |