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B4galnt4 B4galnt4 B4galt1 B4galt1 Galnt6 Galnt6 Gyg1 Gyg1 Galnt7 Galnt7 B4galt5 B4galt5 B4galt7 B4galt7 Large1 Large1 Gmppa Gmppa Ggta1 Ggta1 B4galt6 B4galt6 Cercam Cercam Ext2 Ext2 Has3 Has3 Extl3 Extl3 Cmas Cmas Extl2 Extl2 Csgalnact2 Csgalnact2 Uggt1 Uggt1 Ugcg Ugcg Galnt1 Galnt1 Extl1 Extl1 Galnt18 Galnt18 Glt8d1 Glt8d1 Eif2b3 Eif2b3 Colgalt1 Colgalt1 B4galt2 B4galt2 Gmppb Gmppb B3gat3 B3gat3 A4gnt A4gnt Ext1 Ext1 Glt6d1 Glt6d1 Colgalt2 Colgalt2 Pomgnt1 Pomgnt1 B4galnt3 B4galnt3 Abo Abo Glt8d2 Glt8d2 Large2 Large2 Galnt13 Galnt13 Abo3 Abo3 Csgalnact1 Csgalnact1 Uap1l1 Uap1l1 Chsy1 Chsy1 Dpm1 Dpm1 Has1 Has1 Galnt11 Galnt11 Galnt12 Galnt12 Ggta1l1 Ggta1l1 LOC502618 LOC502618 Uap1 Uap1 Gxylt1 Gxylt1 Galnt9 Galnt9 Plod2 Plod2 B4galnt1 B4galnt1 B3galt5 B3galt5 Mfng Mfng Galnt14 Galnt14 Plod1 Plod1 B3galt1 B3galt1 B3gat1 B3gat1 Crppa Crppa A3galt2 A3galt2 Galnt3 Galnt3 Gxylt2 Gxylt2 Mgat1 Mgat1 Alg5 Alg5 M0RE11_RAT M0RE11_RAT M0RBM6_RAT M0RBM6_RAT Abo2 Abo2 Galntl5 Galntl5 Galnt15 Galnt15 Ugp2 Ugp2 B3gat2 B3gat2 A4galt A4galt B3gntl1 B3gntl1 Chsy3 Chsy3 Galnt2 Galnt2 Plod3 Plod3 Eif2b5 Eif2b5 Xxylt1 Xxylt1 Galnt10 Galnt10 B4galt4 B4galt4 B4galt3 B4galt3 Mgat2 Mgat2 Galnt5 Galnt5 Galnt16 Galnt16 Has2 Has2 B3glct B3glct
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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B4galnt4Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (1033 aa)
B4galt1UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1 (Mapped), isoform CRA_a. (399 aa)
Galnt6Polypeptide N-acetylgalactosaminyltransferase. (622 aa)
Gyg1Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. (361 aa)
Galnt7N-acetylgalactosaminyltransferase 7; Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D- galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide s [...] (657 aa)
B4galt5Beta-1,4-galactosyltransferase 5. (388 aa)
B4galt7Beta-1,4-galactosyltransferase 7. (381 aa)
Large1LARGE xylosyl- and glucuronyltransferase 1. (756 aa)
GmppaMannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. (425 aa)
Ggta1N-acetyllactosaminide alpha-1,3-galactosyltransferase; Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. Preferentially glycosylates proteins, can synthesize galactose-alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3). Belongs to the glycosyltransferase 6 family. (371 aa)
B4galt6Beta-1,4-galactosyltransferase 6; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). (383 aa)
CercamProbable inactive glycosyltransferase 25 family member 3; Probable cell adhesion protein involved in leukocyte transmigration across the blood-brain barrier. Does not express any beta-galactosyltransferase activity in vitro. Belongs to the glycosyltransferase 25 family. (572 aa)
Ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (718 aa)
Has3Hyaluronan synthase 3. (554 aa)
Extl3Exostoses (Multiple)-like 3, isoform CRA_a; Belongs to the glycosyltransferase 47 family. (919 aa)
CmasN-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity). (432 aa)
Extl2Exostoses (Multiple)-like 2, isoform CRA_a. (329 aa)
Csgalnact2Hexosyltransferase. (542 aa)
Uggt1UDP-glucose:glycoprotein glucosyltransferase 1; Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. Belongs to the glycosyltransferase 8 family. (1551 aa)
UgcgCeramide glucosyltransferase; Catalyzes at the cytosolic surface of the Golgi, the initial step of the glucosylceramide-based glycosphingolipid/GSL synthetic pathway, the transfer of glucose from UDP-glucose to ceramide to produce glucosylceramide/GlcCer. Glucosylceramide is the core component of glycosphingolipids/GSLs, amphipathic molecules consisting of a ceramide lipid moiety embedded in the outer leaflet of the membrane, linked to one of hundreds of different externally oriented oligosaccharide structures. Glycosphingolipids are essential components of membrane microdomains that m [...] (394 aa)
Galnt1Polypeptide N-acetylgalactosaminyltransferase 1 soluble form; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7; Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. (559 aa)
Extl1Exostoses (Multiple)-like 1 (Predicted); Belongs to the glycosyltransferase 47 family. (670 aa)
Galnt18Polypeptide N-acetylgalactosaminyltransferase. (607 aa)
Glt8d1Glycosyltransferase 8 domain-containing protein 1. (399 aa)
Eif2b3Translation initiation factor eIF-2B subunit gamma; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. (452 aa)
Colgalt1Glycosyltransferase 25 domain containing 1 (Predicted). (617 aa)
B4galt2UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2 (Predicted). (369 aa)
GmppbGDP-mannose pyrophosphorylase B (Predicted), isoform CRA_a. (360 aa)
B3gat3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (335 aa)
A4gntAlpha-1,4-N-acetylglucosaminyltransferase. (342 aa)
Ext1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
Glt6d1Glycosyltransferase 6 domain-containing protein 1; Belongs to the glycosyltransferase 6 family. (311 aa)
Colgalt2Collagen beta(1-O)galactosyltransferase 2. (624 aa)
Pomgnt1Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1; Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose. (660 aa)
B4galnt3Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (989 aa)
AboHisto-blood group ABO system transferase 2; Posseses strong B transferase activity and a weak A transferase activity; Belongs to the glycosyltransferase 6 family. (334 aa)
Glt8d2Glycosyltransferase 8 domain-containing 2. (350 aa)
Large2LARGE xylosyl- and glucuronyltransferase 2; Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate- 6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by [...] (690 aa)
Galnt13Polypeptide N-acetylgalactosaminyltransferase 13; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a much stronger activity than GALNT1 to transfer GalNAc to mucin peptides, such as Muc5Ac and Muc7. Able to glycosylate SDC3. May be responsible for the synthesis of Tn antigen in neuronal cells (By similarity). Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. (556 aa)
Abo3Histo-blood group ABO system transferase 1; Posseses strong A transferase activity and a weak B transferase activity. (346 aa)
Csgalnact1Hexosyltransferase. (530 aa)
Uap1l1UDP-N-acetylglucosamine pyrophosphorylase 1-like 1. (507 aa)
Chsy1Hexosyltransferase. (788 aa)
Dpm1Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (260 aa)
Has1Hyaluronan synthase 1. (583 aa)
Galnt11Polypeptide N-acetylgalactosaminyltransferase 11; Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O- glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme a [...] (609 aa)
Galnt12Polypeptide N-acetylgalactosaminyltransferase. (579 aa)
Ggta1l1N-acetyllactosaminide alpha-1,3-galactosyltransferase-like 1; Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. (321 aa)
LOC502618ABO-family member 6. (332 aa)
Uap1UDP-N-acetylglucosamine pyrophosphorylase 1. (521 aa)
Gxylt1Glucoside xylosyltransferase 1; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. (435 aa)
Galnt9Polypeptide N-acetylgalactosaminyltransferase. (604 aa)
Plod2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. (758 aa)
B4galnt1Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and asialo-GM2; Belongs to the glycosyltransferase 2 family. (533 aa)
B3galt5Hexosyltransferase. (308 aa)
MfngMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (321 aa)
Galnt14Polypeptide N-acetylgalactosaminyltransferase. (552 aa)
Plod1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1; Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity). Forms hydroxylysine residues in -Xaa-Lys- Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (By similarity). (728 aa)
B3galt1Hexosyltransferase. (326 aa)
B3gat1Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo- fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl- sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regar [...] (347 aa)
CrppaD-ribitol-5-phosphate cytidylyltransferase; Cytidylyltransferase required for protein O-linked mannosylation (By similarity). Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate. CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4- (phosphate-6-)mannose), a carbohydrate structure present in alpha- dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity). Shows ac [...] (447 aa)
A3galt2Alpha-1,3-galactosyltransferase 2; Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Synthesis of iGb3 is the initial step in the formation of the isoglobo- series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids. Can glycosylate only lipids and not proteins and i [...] (339 aa)
Galnt3Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
Gxylt2Glucoside xylosyltransferase 2. (444 aa)
Mgat1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. (447 aa)
Alg5ALG5, dolichyl-phosphate beta-glucosyltransferase. (324 aa)
M0RE11_RATUncharacterized protein. (327 aa)
M0RBM6_RATGlyco_trans_2-like domain-containing protein. (56 aa)
Abo2Histo-blood group ABO system transferase 2. (334 aa)
Galntl5UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5. (443 aa)
Galnt15Polypeptide N-acetylgalactosaminyltransferase. (641 aa)
Ugp2UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
B3gat2Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins. Substrates include asialo- orosomucoid (ASOR), paragloboside (lacto-N-neotetraosylceramide), Gal- beta-1,4-GlcNAc-beta-1,3-Gal-beta-1,4-Glc-pyridylamine and Gal-beta- 1,3-GlcNAc-beta-1,3-Gal-beta-1,4-Glc-pyridylamine. (324 aa)
A4galtLactosylceramide 4-alpha-galactosyltransferase; Catalyzes the transfer of galactose from UDP-alpha-D- galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl- (1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer (By similarity). Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (By similarity). (360 aa)
B3gntl1UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Putative glycosyltransferase; Belongs to the glycosyltransferase 2 family. (357 aa)
Chsy3Hexosyltransferase. (886 aa)
Galnt2Polypeptide N-acetylgalactosaminyltransferase. (542 aa)
Plod3Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3; Multifunctional enzyme that catalyzes a series of post- translational modifications on Lys residues in procollagen. Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens (By similarity). Plays a redundant role in catalyzing the transfer of galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine (By similarity). Has an essential role by catalyzing the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosy [...] (741 aa)
Eif2b5Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. (716 aa)
Xxylt1Xyloside xylosyltransferase 1. (392 aa)
Galnt10Polypeptide N-acetylgalactosaminyltransferase 10; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. (603 aa)
B4galt4Beta-1,4-galactosyltransferase 4; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. (344 aa)
B4galt3Beta-1,4-galactosyltransferase 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. (395 aa)
Mgat2Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Plays an essential role in protein N-glycosylation. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) onto the free terminal mannose moiety in the core structure of the nascent N-linked glycan chain, giving rise to the second branch in complex glycans. (442 aa)
Galnt5Polypeptide N-acetylgalactosaminyltransferase 5; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward EA2 peptide substrate, but has a weak activity toward Muc2, Muc1b, rMuc-2 or mG-Muc substrates; Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. (930 aa)
Galnt16Polypeptide N-acetylgalactosaminyltransferase. (558 aa)
Has2Hyaluronan synthase 2; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. M [...] (552 aa)
B3glctBeta 3-glucosyltransferase. (485 aa)
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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