(10 nodes) Unmethylated CpG binding network (Cavia porcellus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100724130	TIR domain-containing protein. (1029 aa)
	KDM2B	Lysine demethylase 2B. (1306 aa)
	FBXL19	F-box and leucine rich repeat protein 19. (674 aa)
	MBD1	Methyl-CpG binding domain protein 1. (659 aa)
	KMT2B	Lysine methyltransferase 2B. (2689 aa)
	CFAP53	Cilia and flagella associated protein 53. (404 aa)
	Kmt2a	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (2938 aa)
	CXXC1	CXXC finger protein 1. (554 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (504 aa)
	KDM2A	Lysine demethylase 2A. (1161 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CXXC1	KMT2B	ENSCPOP00000018559	ENSCPOP00000003358	CXXC finger protein 1.	Lysine methyltransferase 2B.	0.547
CXXC1	Kmt2a	ENSCPOP00000018559	ENSCPOP00000005242	CXXC finger protein 1.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.547
FBXL19	KMT2B	ENSCPOP00000026753	ENSCPOP00000003358	F-box and leucine rich repeat protein 19.	Lysine methyltransferase 2B.	0.441
FBXL19	Kmt2a	ENSCPOP00000026753	ENSCPOP00000005242	F-box and leucine rich repeat protein 19.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.441
KDM2A	KMT2B	ENSCPOP00000006433	ENSCPOP00000003358	Lysine demethylase 2A.	Lysine methyltransferase 2B.	0.502
KDM2A	Kmt2a	ENSCPOP00000006433	ENSCPOP00000005242	Lysine demethylase 2A.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.502
KDM2B	KMT2B	ENSCPOP00000027446	ENSCPOP00000003358	Lysine demethylase 2B.	Lysine methyltransferase 2B.	0.507
KDM2B	Kmt2a	ENSCPOP00000027446	ENSCPOP00000005242	Lysine demethylase 2B.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.550
KMT2B	CXXC1	ENSCPOP00000003358	ENSCPOP00000018559	Lysine methyltransferase 2B.	CXXC finger protein 1.	0.547
KMT2B	FBXL19	ENSCPOP00000003358	ENSCPOP00000026753	Lysine methyltransferase 2B.	F-box and leucine rich repeat protein 19.	0.441
KMT2B	KDM2A	ENSCPOP00000003358	ENSCPOP00000006433	Lysine methyltransferase 2B.	Lysine demethylase 2A.	0.502
KMT2B	KDM2B	ENSCPOP00000003358	ENSCPOP00000027446	Lysine methyltransferase 2B.	Lysine demethylase 2B.	0.507
KMT2B	Kmt2a	ENSCPOP00000003358	ENSCPOP00000005242	Lysine methyltransferase 2B.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.825
Kmt2a	CXXC1	ENSCPOP00000005242	ENSCPOP00000018559	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	CXXC finger protein 1.	0.547
Kmt2a	FBXL19	ENSCPOP00000005242	ENSCPOP00000026753	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	F-box and leucine rich repeat protein 19.	0.441
Kmt2a	KDM2A	ENSCPOP00000005242	ENSCPOP00000006433	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	Lysine demethylase 2A.	0.502
Kmt2a	KDM2B	ENSCPOP00000005242	ENSCPOP00000027446	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	Lysine demethylase 2B.	0.550
Kmt2a	KMT2B	ENSCPOP00000005242	ENSCPOP00000003358	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	Lysine methyltransferase 2B.	0.825