STRINGSTRING
LOC100714297 LOC100714297 CUL3 CUL3 RNF4 RNF4 RBX1 RBX1 UBE2B UBE2B NEDD4L NEDD4L UBE2Q2 UBE2Q2 Ube2a Ube2a UBE2H UBE2H ENSCPOP00000022546 ENSCPOP00000022546 RNF5 RNF5 BFAR BFAR UBE2G2 UBE2G2 UBE2C UBE2C UBE2D1 UBE2D1 SYVN1 SYVN1 RNF126 RNF126 CUL1 CUL1 H0VZC1_CAVPO H0VZC1_CAVPO LOC100727489 LOC100727489 RNF115 RNF115 ITCH ITCH UBE3C UBE3C Skp2 Skp2 FBXO38 FBXO38 TNFAIP3 TNFAIP3 UBE2T UBE2T UBR5 UBR5 RNF6 RNF6 LOC100730225 LOC100730225 ARIH2 ARIH2 RNF187 RNF187 Ttc3 Ttc3 UBE2E3 UBE2E3 UBE3A UBE3A MARCHF6 MARCHF6 ENSCPOP00000032781 ENSCPOP00000032781 ENSCPOP00000032613 ENSCPOP00000032613 DTX3L DTX3L UBE2D4 UBE2D4 UBE2D2 UBE2D2 RNF8 RNF8 UBE2E2 UBE2E2 KLHL3 KLHL3 UBE2R2 UBE2R2 PELI1 PELI1 RFFL RFFL TRIM32 TRIM32 ZNRF1 ZNRF1 UBE2G1 UBE2G1 CDC34 CDC34 RNF152 RNF152 ENSCPOP00000027080 ENSCPOP00000027080 LOC100715128 LOC100715128 UBE2K UBE2K UBE2D3 UBE2D3 HACE1 HACE1 UBE2E1 UBE2E1 AMFR AMFR RNF34 RNF34 RNF146 RNF146 RNF216 RNF216 BTRC BTRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100714297Uncharacterized protein. (464 aa)
CUL3Cullin 3; Belongs to the cullin family. (765 aa)
RNF4Ring finger protein 4. (190 aa)
RBX1Ring-box 1. (108 aa)
UBE2BUbiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (992 aa)
UBE2Q2Ubiquitin conjugating enzyme E2 Q2. (373 aa)
Ube2aUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (326 aa)
UBE2HUbiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
ENSCPOP00000022546Uncharacterized protein. (294 aa)
RNF5Ring finger protein 5. (180 aa)
BFARBifunctional apoptosis regulator. (450 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
SYVN1Synoviolin 1. (605 aa)
RNF126Ring finger protein 126. (313 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
H0VZC1_CAVPOUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
LOC100727489Uncharacterized protein. (534 aa)
RNF115Ring finger protein 115. (280 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
UBE3CUbiquitin protein ligase E3C. (1083 aa)
Skp2F-box domain-containing protein. (424 aa)
FBXO38F-box protein 38. (1186 aa)
TNFAIP3TNF alpha induced protein 3. (789 aa)
UBE2TUbiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (205 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2649 aa)
RNF6Ring finger protein 6. (622 aa)
LOC100730225BTB domain-containing protein. (659 aa)
ARIH2RBR-type E3 ubiquitin transferase. (492 aa)
RNF187Ring finger protein 187. (235 aa)
Ttc3TPR_REGION domain-containing protein. (212 aa)
UBE2E3Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (874 aa)
MARCHF6Membrane associated ring-CH-type finger 6. (903 aa)
ENSCPOP00000032781UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
ENSCPOP00000032613F-box domain-containing protein. (390 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (719 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (122 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (486 aa)
UBE2E2Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
KLHL3Kelch like family member 3. (601 aa)
UBE2R2Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
RFFLRing finger and FYVE like domain containing E3 ubiquitin protein ligase. (398 aa)
TRIM32Tripartite motif containing 32. (653 aa)
ZNRF1Zinc and ring finger 1. (227 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
CDC34Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (228 aa)
RNF152Ring finger protein 152. (203 aa)
ENSCPOP00000027080UBIQUITIN_CONJUGAT_2 domain-containing protein. (143 aa)
LOC100715128Uncharacterized protein. (474 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (874 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
AMFRAutocrine motility factor receptor. (643 aa)
RNF34Ring finger protein 34. (376 aa)
RNF146Ring finger protein 146. (356 aa)
RNF216Ring finger protein 216. (935 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (582 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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