STRINGSTRING
NPPC NPPC SCUBE2 SCUBE2 RUNX3 RUNX3 TGFB1 TGFB1 RUNX2 RUNX2 WNT2B WNT2B LOC103088826 LOC103088826 SIX2 SIX2 SNX19 SNX19 TWSG1 TWSG1 BMPR1A BMPR1A MEF2D MEF2D AXIN2 AXIN2 LOC103086357 LOC103086357 OSR2 OSR2 GPLD1 GPLD1 CTGF CTGF IFT80 IFT80 EXT2 EXT2 SERPINH1 SERPINH1 WNT10B WNT10B TRIP11 TRIP11 SOX9 SOX9 EXT1 EXT1 NOV NOV SLC39A14 SLC39A14 ATF2 ATF2 SMPD3 SMPD3 LOC103073106 LOC103073106 MATN1 MATN1 RARG RARG ANXA6 ANXA6 GDF5 GDF5 SULF1 SULF1 CHST11 CHST11 RUNX1 RUNX1 BMP2 BMP2 WNT5B WNT5B ARID5A ARID5A GLI3 GLI3 BMPR2 BMPR2 LOC103089741 LOC103089741 RB1 RB1 HOXA11 HOXA11 CREB3L2 CREB3L2 FGF18 FGF18 MEF2C MEF2C SFRP2 SFRP2 COL3A1 COL3A1 ADAMTS12 ADAMTS12 NFIB NFIB MEX3C MEX3C CTNNB1 CTNNB1 CYTL1 CYTL1 COL2A1 COL2A1 OSR1 OSR1 PTH1R PTH1R HIF1A HIF1A ACAN ACAN BMP4 BMP4 SULF2 SULF2 HMGA2 HMGA2 IHH IHH SCXB SCXB FGF9 FGF9 ECM1 ECM1 BMPR1B BMPR1B LTBP3 LTBP3 IMPAD1 IMPAD1 COMP COMP LOC103073422 LOC103073422 COL11A2 COL11A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NPPCC-type natriuretic peptide. (126 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1. (967 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (433 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
RUNX2Runt-related transcription factor 2 isoform X1. (550 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
SIX2Homeobox protein SIX2. (296 aa)
SNX19Sorting nexin-19. (1005 aa)
TWSG1Twisted gastrulation protein homolog 1. (222 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MEF2DMyocyte-specific enhancer factor 2D isoform X2. (511 aa)
AXIN2Axin-2. (846 aa)
LOC103086357Protein scribble homolog. (347 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D isoform X1. (839 aa)
CTGFConnective tissue growth factor. (349 aa)
IFT80Intraflagellar transport protein 80 homolog. (777 aa)
EXT2Exostosin-2; Belongs to the glycosyltransferase 47 family. (718 aa)
SERPINH1Serpin H1; Belongs to the serpin family. (418 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
TRIP11Thyroid receptor-interacting protein 11. (1980 aa)
SOX9Transcription factor SOX-9 isoform X1. (509 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (750 aa)
NOVProtein NOV homolog isoform X1. (358 aa)
SLC39A14Zinc transporter ZIP14. (523 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
SMPD3Sphingomyelin phosphodiesterase 3 isoform X1. (654 aa)
LOC103073106Uncharacterized protein LOC103073106. (173 aa)
MATN1Cartilage matrix protein. (495 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
ANXA6Annexin. (672 aa)
GDF5Growth/differentiation factor 5. (499 aa)
SULF1Extracellular sulfatase Sulf-1. (1096 aa)
CHST11Carbohydrate sulfotransferase. (343 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
ARID5AAT-rich interactive domain-containing protein 5A. (675 aa)
GLI3Transcriptional activator GLI3. (1590 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LOC103089741Aggrecan core protein-like. (251 aa)
RB1Retinoblastoma-associated protein isoform X1. (929 aa)
HOXA11Homeobox protein Hox-A11. (317 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
COL3A1Collagen alpha-1(III) chain-like. (1462 aa)
ADAMTS12A disintegrin and metalloproteinase with thrombospondin motifs 12. (1609 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (576 aa)
MEX3CRNA-binding E3 ubiquitin-protein ligase MEX3C. (652 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
CYTL1Cytokine-like protein 1. (135 aa)
COL2A1Collagen alpha-1(II) chain isoform X1. (1487 aa)
OSR1Protein odd-skipped-related 1. (267 aa)
PTH1RParathyroid hormone/parathyroid hormone-related peptide receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (591 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X2. (822 aa)
ACANAggrecan core protein. (2042 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
SULF2Extracellular sulfatase Sulf-2 isoform X2. (857 aa)
HMGA2High mobility group protein HMGI-C. (109 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
SCXBBasic helix-loop-helix transcription factor scleraxis. (203 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ECM1Extracellular matrix protein 1 isoform X1. (578 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3 isoform X1. (1301 aa)
IMPAD1Inositol monophosphatase 3. (359 aa)
COMPCartilage oligomeric matrix protein isoform X1. (756 aa)
LOC103073422LOW QUALITY PROTEIN: short stature homeobox protein 2-like. (359 aa)
COL11A2Collagen alpha-2(XI) chain isoform X1. (1736 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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