49 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103072950	Uncharacterized protein LOC103072950. (442 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	USP8	LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1116 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (584 aa)
	NRG3	Pro-neuregulin-3, membrane-bound isoform-like isoform X1. (613 aa)
	ERBB2IP	Protein LAP2 isoform X1. (1421 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	PRKCE	Protein kinase C; Belongs to the protein kinase superfamily. (493 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	MEMO1	Protein MEMO1 isoform X1. (297 aa)
	LOC103076438	ubiquitin-40S ribosomal protein S27a-like. (155 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
	UBC	polyubiquitin-C. (462 aa)
	ERAS	GTPase ERas. (233 aa)
	CUL5	Cullin-5; Belongs to the cullin family. (780 aa)
	SOS1	Son of sevenless homolog 1. (1333 aa)
	SRC	Tyrosine-protein kinase. (548 aa)
	KRAS	GTPase KRas. (188 aa)
	NRG1	Pro-neuregulin-3, membrane-bound isoform-like isoform X1. (641 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1206 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	GRB7	LOW QUALITY PROTEIN: growth factor receptor-bound protein 7. (557 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	NRAS	GTPase NRas. (189 aa)
	BTC	Probetacellulin. (178 aa)
	PTPN18	Tyrosine-protein phosphatase non-receptor type 18 isoform X1. (454 aa)
	EREG	Proepiregulin. (163 aa)
	UBA52	ubiquitin-60S ribosomal protein L40. (128 aa)
	CDC37	Hsp90 co-chaperone Cdc37. (379 aa)
	NRG2	Pro-neuregulin-2, membrane-bound isoform. (757 aa)
	UBB	polyubiquitin-C isoform X1. (305 aa)
	MATK	Tyrosine-protein kinase. (485 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (843 aa)
	HSP90AA1	Heat shock protein HSP 90-alpha. (732 aa)
	STUB1	E3 ubiquitin-protein ligase CHIP. (303 aa)
	NRG4	Pro-neuregulin-4, membrane-bound isoform. (116 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1308 aa)
	LOC103076597	ubiquitin-40S ribosomal protein S27a-like. (187 aa)
	ERBB3	Receptor tyrosine-protein kinase erbB-3. (1338 aa)
	RNF41	E3 ubiquitin-protein ligase NRDP1 isoform X1. (317 aa)
	DIAPH1	Protein diaphanous homolog 1 isoform X2. (1236 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12 isoform X1. (782 aa)
	LOC103083100	ubiquitin-60S ribosomal protein L40-like. (116 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTC	EGF	A0A340XSV2	A0A340XVB5	Probetacellulin.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.742
BTC	ERBB2	A0A340XSV2	A0A340XV51	Probetacellulin.	Receptor protein-tyrosine kinase.	0.650
BTC	ERBB3	A0A340XSV2	A0A340Y622	Probetacellulin.	Receptor tyrosine-protein kinase erbB-3.	0.853
BTC	ERBB4	A0A340XSV2	A0A340Y8S3	Probetacellulin.	Receptor protein-tyrosine kinase.	0.985
BTC	EREG	A0A340XSV2	A0A340XPM9	Probetacellulin.	Proepiregulin.	0.738
BTC	GRB2	A0A340XSV2	A0A340X5P7	Probetacellulin.	Growth factor receptor-bound protein 2 isoform X1.	0.457
BTC	HBEGF	A0A340XSV2	A0A340XJA1	Probetacellulin.	Proheparin-binding EGF-like growth factor.	0.833
BTC	KRAS	A0A340XSV2	A0A340WCQ7	Probetacellulin.	GTPase KRas.	0.539
BTC	NRG1	A0A340XSV2	A0A340Y119	Probetacellulin.	Pro-neuregulin-3, membrane-bound isoform-like isoform X1.	0.590
BTC	NRG2	A0A340XSV2	A0A340XN31	Probetacellulin.	Pro-neuregulin-2, membrane-bound isoform.	0.590
BTC	NRG4	A0A340XSV2	A0A340YK86	Probetacellulin.	Pro-neuregulin-4, membrane-bound isoform.	0.531
BTC	PIK3CA	A0A340XSV2	A0A340Y0D6	Probetacellulin.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family.	0.527
BTC	SRC	A0A340XSV2	A0A340WDY6	Probetacellulin.	Tyrosine-protein kinase.	0.559
CDC37	CUL5	A0A340XNW7	A0A340WJJ4	Hsp90 co-chaperone Cdc37.	Cullin-5; Belongs to the cullin family.	0.491
CDC37	ERBB2	A0A340XNW7	A0A340XV51	Hsp90 co-chaperone Cdc37.	Receptor protein-tyrosine kinase.	0.685
CDC37	HSP90AA1	A0A340XNW7	A0A340X2A4	Hsp90 co-chaperone Cdc37.	Heat shock protein HSP 90-alpha.	0.987
CDC37	SRC	A0A340XNW7	A0A340WDY6	Hsp90 co-chaperone Cdc37.	Tyrosine-protein kinase.	0.419
CDC37	STUB1	A0A340XNW7	A0A340X3E1	Hsp90 co-chaperone Cdc37.	E3 ubiquitin-protein ligase CHIP.	0.525
CDC37	UBB	A0A340XNW7	A0A340XMW2	Hsp90 co-chaperone Cdc37.	polyubiquitin-C isoform X1.	0.436
CDC37	UBC	A0A340XNW7	A0A340WNW1	Hsp90 co-chaperone Cdc37.	polyubiquitin-C.	0.436