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pyk pyk CCH71883.1 CCH71883.1 atpB atpB atpE atpE atpF atpF atpH atpH atpA atpA atpG atpG atpD atpD atpC atpC CCH72394.1 CCH72394.1 ndk ndk fda fda fbaA fbaA pdhB pdhB CCH72906.1 CCH72906.1 CCH72943.1 CCH72943.1 SucB SucB eno eno gpmA gpmA CCH74251.1 CCH74251.1 pgi pgi tpiA tpiA pgk pgk CCH74672.1 CCH74672.1 aceE aceE pfp pfp CCH75397.1 CCH75397.1 CCH75766.1 CCH75766.1 CCH75773.1 CCH75773.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pykPyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. (480 aa)
CCH71883.1Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (213 aa)
atpBATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (285 aa)
atpEATP synthase (subunit c, component F0); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (68 aa)
atpFATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (200 aa)
atpHATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (269 aa)
atpAATP synthase (subunit alpha, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (544 aa)
atpGATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (302 aa)
atpDATP synthase (subunit beta, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (490 aa)
atpCATP synthase, epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (87 aa)
CCH72394.1Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (201 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
fdaFructose-bisphosphate aldolase class 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (295 aa)
fbaAFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa)
pdhBPyruvate dehydrogenase E1 component subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (324 aa)
CCH72906.1Phosphoglycerate mutase family protein; Belongs to the phosphoglycerate mutase family. (247 aa)
CCH72943.1Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Belongs to the dGTPase family. Type 2 subfamily. (358 aa)
SucB2-oxoglutarate dehydrogenase complex (dihydrolipoamide transsuccinylase, E2 subunit) (fragment); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (230 aa)
enoEnolase / Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
gpmAPhosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (245 aa)
CCH74251.1Putative pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit) (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (264 aa)
pgiGlucosephosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family. (556 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (264 aa)
pgkPhosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family. (401 aa)
CCH74672.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (299 aa)
aceEPyruvate dehydrogenase, decarboxylase component E1, thiamin-binding (pdhA); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (924 aa)
pfpPyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (400 aa)
CCH75397.1MutT-like protein. (160 aa)
CCH75766.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (254 aa)
CCH75773.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (222 aa)
Your Current Organism:
Tetrasphaera australiensis
NCBI taxonomy Id: 1193182
Other names: T. australiensis Ben110, Tetrasphaera australiensis Ben110, Tetrasphaera australiensis str. Ben110, Tetrasphaera australiensis strain Ben110
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