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ndk ndk tmk tmk adk adk cmk cmk gmk gmk tdk tdk pyrH pyrH CCH75516.1 CCH75516.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (209 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (191 aa)
cmkCytidylate kinase. (230 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (189 aa)
tdkThymidine kinase. (224 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (256 aa)
CCH75516.1Putative ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (217 aa)
Your Current Organism:
Tetrasphaera australiensis
NCBI taxonomy Id: 1193182
Other names: T. australiensis Ben110, Tetrasphaera australiensis Ben110, Tetrasphaera australiensis str. Ben110, Tetrasphaera australiensis strain Ben110
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