(93 nodes) Mixed, incl. Small GTPase mediated signal transduction, and Regulation of small GTPase mediated signal transduction network (Pediculus humanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E0V9M2_PEDHC	Uncharacterized protein. (188 aa)
	E0VA13_PEDHC	Rhogtpase, putative. (760 aa)
	E0VAR1_PEDHC	Rho/RAC guanine nucleotide exchange factor, putative. (1385 aa)
	E0VCL5_PEDHC	Ephrin-B1 precursor, putative; Belongs to the ephrin family. (241 aa)
	E0VD19_PEDHC	Leucine-rich repeat protein SHOC-2, putative. (608 aa)
	E0VD29_PEDHC	N-chimaerin, putative. (451 aa)
	E0VE05_PEDHC	Breakpoint cluster region protein, putative. (1177 aa)
	E0VE14_PEDHC	Leucine-rich repeat-containing protein 1, lrrc1/lap4, putative. (1463 aa)
	E0VEC6_PEDHC	Uncharacterized protein. (994 aa)
	E0VEI8_PEDHC	GTP-binding protein Di-Ras2, putative. (214 aa)
	E0VEP4_PEDHC	Dynamin-associated protein, putative. (1558 aa)
	E0VEU0_PEDHC	Uncharacterized protein. (1571 aa)
	E0VF04_PEDHC	Uncharacterized protein. (800 aa)
	E0VF05_PEDHC	Uncharacterized protein. (73 aa)
	E0VF58_PEDHC	Serine/threonine-protein kinase, putative. (709 aa)
	E0VF59_PEDHC	Huntingtin-associated protein-interacting protein, putative. (2251 aa)
	E0VFI4_PEDHC	Guanine nucleotide-binding protein G(Q), subunit alpha, putative. (217 aa)
	E0VFR4_PEDHC	Uncharacterized protein. (552 aa)
	E0VFR7_PEDHC	LBC oncogene, putative. (391 aa)
	E0VFR9_PEDHC	Uncharacterized protein. (425 aa)
	E0VFY5_PEDHC	DH domain-containing protein. (1156 aa)
	E0VGB8_PEDHC	Ras GTP-ase activating protein with iq motif, putative. (1518 aa)
	E0VGT7_PEDHC	GTP-binding protein Di-Ras2, putative. (274 aa)
	E0VGY2_PEDHC	Ras, putative. (226 aa)
	E0VIB0_PEDHC	GTP-binding protein alpha subunit, gna, putative. (368 aa)
	E0VID5_PEDHC	Rap1 and, putative. (184 aa)
	E0VIG3_PEDHC	Histone H1-II-1, putative. (354 aa)
	E0VIQ6_PEDHC	Uncharacterized protein. (57 aa)
	E0VJF3_PEDHC	Ras GTPase-activating protein, putative. (874 aa)
	E0VJI8_PEDHC	Myosin IIIB, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (783 aa)
	E0VK42_PEDHC	Ral, putative. (202 aa)
	E0VKR8_PEDHC	Uncharacterized protein. (83 aa)
	E0VKR9_PEDHC	Rap1 GTPase-activating protein, putative. (578 aa)
	E0VKU8_PEDHC	Collybistin, putative. (687 aa)
	E0VLQ2_PEDHC	Predicted protein. (945 aa)
	E0VLS6_PEDHC	Rho-GTPase-activating protein, putative. (1575 aa)
	E0VLX6_PEDHC	Uncharacterized protein. (1129 aa)
	E0VMH5_PEDHC	GTPase_rho, putative. (229 aa)
	E0VMJ0_PEDHC	Non-specific serine/threonine protein kinase. (466 aa)
	E0VMP6_PEDHC	14-3-3 protein epsilon, putative; Belongs to the 14-3-3 family. (262 aa)
	E0VMX1_PEDHC	ARF GTPase-activating protein GIT2, putative. (632 aa)
	E0VMY4_PEDHC	Rho/RAC guanine nucleotide exchange factor, putative. (1752 aa)
	E0VNE1_PEDHC	Ral guanine nucleotide exchange factor, putative. (523 aa)
	E0VNR7_PEDHC	SH3 domain-containing protein. (709 aa)
	E0VNR8_PEDHC	WW domain-containing protein. (265 aa)
	E0VNR9_PEDHC	Rho GTPase activating protein, putative. (1303 aa)
	E0VNS7_PEDHC	RAC GTPase, putative. (192 aa)
	E0VP23_PEDHC	Rap GTPase-activating protein, putative. (1518 aa)
	E0VP99_PEDHC	GTP-binding protein, putative. (291 aa)
	E0VPT4_PEDHC	Neurofibromin, putative. (2686 aa)
	E0VPX8_PEDHC	Serine/threonine-protein kinase NIM1, putative. (649 aa)
	E0VQ20_PEDHC	F5/8 type C domain-containing protein. (140 aa)
	E0VQ90_PEDHC	cAMP-dependent protein kinase catalytic subunit, putative. (533 aa)
	E0VQF2_PEDHC	RAC GTPase, putative. (199 aa)
	E0VQH6_PEDHC	GTP-binding protein Rit2, putative. (264 aa)
	E0VQQ5_PEDHC	Ras, putative. (191 aa)
	E0VR41_PEDHC	Non-specific serine/threonine protein kinase. (631 aa)
	E0VS88_PEDHC	Mitogen-activated protein kinase ERK-A, putative; Belongs to the protein kinase superfamily. (400 aa)
	E0VSQ9_PEDHC	Rho GDP-dissociation inhibitor, putative. (198 aa)
	E0VSX8_PEDHC	RAC GTPase, putative. (191 aa)
	E0VSY6_PEDHC	BTB domain-containing protein. (593 aa)
	E0VUJ1_PEDHC	Rho GTPase activating protein, putative. (830 aa)
	E0VUV9_PEDHC	Uncharacterized protein. (109 aa)
	E0VVV9_PEDHC	Dexras1, putative. (333 aa)
	E0VW01_PEDHC	cAMP-dependent protein kinase catalytic subunit, putative. (689 aa)
	E0VX01_PEDHC	Uncharacterized protein. (783 aa)
	E0VX02_PEDHC	Uncharacterized protein. (644 aa)
	E0VXL7_PEDHC	GTPase HRas, putative. (81 aa)
	E0VXL8_PEDHC	Rap1 and, putative. (115 aa)
	E0VY00_PEDHC	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
	E0VY20_PEDHC	Rho-associated protein kinase, putative; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1368 aa)
	E0VY42_PEDHC	Non-specific serine/threonine protein kinase. (715 aa)
	E0VZ36_PEDHC	Rap guanine nucleotide exchange factor, putative. (899 aa)
	E0VZ37_PEDHC	Uncharacterized protein. (119 aa)
	E0VZ40_PEDHC	Rap1 and, putative. (201 aa)
	E0VZL2_PEDHC	GTPase_rho, putative. (218 aa)
	E0W001_PEDHC	Titin, putative. (3224 aa)
	E0W002_PEDHC	Golgin IMH1, putative. (584 aa)
	E0W0B7_PEDHC	Uncharacterized protein. (200 aa)
	E0W0D5_PEDHC	GTP-binding protein REM, putative. (274 aa)
	E0W0D7_PEDHC	Uncharacterized protein. (793 aa)
	E0W0Z6_PEDHC	Uncharacterized protein. (114 aa)
	E0W0Z7_PEDHC	Uncharacterized protein. (136 aa)
	E0W0Z8_PEDHC	GTPase_rab, putative. (95 aa)
	E0W0Z9_PEDHC	GTPase_rab, putative. (108 aa)
	E0W1E4_PEDHC	Ephrin type-B receptor 2 precursor, putative. (949 aa)
	E0W238_PEDHC	Sprouty protein evh1 domain containing protein, putative. (238 aa)
	E0W242_PEDHC	Cytoplasmic protein NCK1, putative. (424 aa)
	E0W264_PEDHC	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1772 aa)
	E0W357_PEDHC	GTPase_rho, putative. (249 aa)
	E0W3M1_PEDHC	Still life, sif, putative. (1788 aa)
	E0W3Q3_PEDHC	Uncharacterized protein. (211 aa)
	E0W4G8_PEDHC	GTPase HRas, putative. (61 aa)

Your Current Organism:

Pediculus humanus

NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0V9M2_PEDHC	E0VEP4_PEDHC	E0V9M2	E0VEP4	Uncharacterized protein.	Dynamin-associated protein, putative.	0.853
E0V9M2_PEDHC	E0VF58_PEDHC	E0V9M2	E0VF58	Uncharacterized protein.	Serine/threonine-protein kinase, putative.	0.526
E0V9M2_PEDHC	E0VF59_PEDHC	E0V9M2	E0VF59	Uncharacterized protein.	Huntingtin-associated protein-interacting protein, putative.	0.569
E0V9M2_PEDHC	E0VIG3_PEDHC	E0V9M2	E0VIG3	Uncharacterized protein.	Histone H1-II-1, putative.	0.815
E0V9M2_PEDHC	E0VJF3_PEDHC	E0V9M2	E0VJF3	Uncharacterized protein.	Ras GTPase-activating protein, putative.	0.400
E0V9M2_PEDHC	E0VJI8_PEDHC	E0V9M2	E0VJI8	Uncharacterized protein.	Myosin IIIB, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.570
E0V9M2_PEDHC	E0VKU8_PEDHC	E0V9M2	E0VKU8	Uncharacterized protein.	Collybistin, putative.	0.453
E0V9M2_PEDHC	E0VLQ2_PEDHC	E0V9M2	E0VLQ2	Uncharacterized protein.	Predicted protein.	0.445
E0V9M2_PEDHC	E0VLX6_PEDHC	E0V9M2	E0VLX6	Uncharacterized protein.	Uncharacterized protein.	0.400
E0V9M2_PEDHC	E0VNE1_PEDHC	E0V9M2	E0VNE1	Uncharacterized protein.	Ral guanine nucleotide exchange factor, putative.	0.555
E0V9M2_PEDHC	E0VPT4_PEDHC	E0V9M2	E0VPT4	Uncharacterized protein.	Neurofibromin, putative.	0.542
E0V9M2_PEDHC	E0VS88_PEDHC	E0V9M2	E0VS88	Uncharacterized protein.	Mitogen-activated protein kinase ERK-A, putative; Belongs to the protein kinase superfamily.	0.480
E0V9M2_PEDHC	E0VSQ9_PEDHC	E0V9M2	E0VSQ9	Uncharacterized protein.	Rho GDP-dissociation inhibitor, putative.	0.415
E0V9M2_PEDHC	E0VW01_PEDHC	E0V9M2	E0VW01	Uncharacterized protein.	cAMP-dependent protein kinase catalytic subunit, putative.	0.605
E0VA13_PEDHC	E0VAR1_PEDHC	E0VA13	E0VAR1	Rhogtpase, putative.	Rho/RAC guanine nucleotide exchange factor, putative.	0.471
E0VA13_PEDHC	E0VD29_PEDHC	E0VA13	E0VD29	Rhogtpase, putative.	N-chimaerin, putative.	0.511
E0VA13_PEDHC	E0VE05_PEDHC	E0VA13	E0VE05	Rhogtpase, putative.	Breakpoint cluster region protein, putative.	0.527
E0VA13_PEDHC	E0VEP4_PEDHC	E0VA13	E0VEP4	Rhogtpase, putative.	Dynamin-associated protein, putative.	0.999
E0VA13_PEDHC	E0VF04_PEDHC	E0VA13	E0VF04	Rhogtpase, putative.	Uncharacterized protein.	0.570
E0VA13_PEDHC	E0VF05_PEDHC	E0VA13	E0VF05	Rhogtpase, putative.	Uncharacterized protein.	0.570