(69 nodes) Postsynaptic density network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CLSTN2	Calsyntenin 2. (883 aa)
	GRASP	General receptor for phosphoinositides 1 associated scaffold protein. (182 aa)
	PPP1R9A	Protein phosphatase 1 regulatory subunit 9A. (1114 aa)
	ABHD17B	Abhydrolase domain containing 17B. (289 aa)
	LRFN2	Leucine rich repeat and fibronectin type III domain containing 2. (763 aa)
	IL1RAPL1	Interleukin 1 receptor accessory protein like 1. (669 aa)
	GPHN	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (729 aa)
	MPP6	Membrane palmitoylated protein 6; Belongs to the MAGUK family. (543 aa)
	ABHD17A	Abhydrolase domain containing 17A. (304 aa)
	LOC102461662	Uncharacterized protein. (448 aa)
	K7GCA4_PELSI	PDZ domain-containing protein. (101 aa)
	PPP1R9B	Protein phosphatase 1 regulatory subunit 9B. (731 aa)
	K7GAP2_PELSI	Uncharacterized protein. (196 aa)
	K7GAJ7_PELSI	Uncharacterized protein. (107 aa)
	LRRC4B	Leucine rich repeat containing 4B. (600 aa)
	GRIP1	Glutamate receptor interacting protein 1. (1112 aa)
	CRIPT	CXXC repeat containing interactor of PDZ3 domain. (101 aa)
	LZTS1	Leucine zipper tumor suppressor 1. (617 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (458 aa)
	CADM1	Cell adhesion molecule 1. (404 aa)
	FABP5	Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (131 aa)
	K7G5B9_PELSI	PKD domain-containing protein. (468 aa)
	NPTN	Neuroplastin. (360 aa)
	SORCS1	Sortilin. (487 aa)
	SORCS3	Sortilin related VPS10 domain containing receptor 3. (990 aa)
	GSG1L	Uncharacterized protein. (273 aa)
	NETO2	Neuropilin and tolloid like 2. (531 aa)
	K7FUC6_PELSI	Ca_chan_IQ domain-containing protein. (1283 aa)
	GSG1	Germ cell associated 1. (317 aa)
	MPP2	Membrane palmitoylated protein 2; Belongs to the MAGUK family. (497 aa)
	ADAM22	ADAM metallopeptidase domain 22. (828 aa)
	LRRC4	Leucine rich repeat containing 4. (569 aa)
	LIN7A	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (209 aa)
	ARHGEF9	Cdc42 guanine nucleotide exchange factor 9. (523 aa)
	HOMER2	Homer scaffold protein 2. (361 aa)
	INSYN2A	Inhibitory synaptic factor 2A. (482 aa)
	CLSTN3	Calsyntenin 3. (604 aa)
	LZTS3	Leucine zipper tumor suppressor family member 3. (663 aa)
	SHANK2	SAM domain-containing protein. (1171 aa)
	LOC102452389	Fibronectin type-III domain-containing protein. (633 aa)
	K7FAF2_PELSI	ANK_REP_REGION domain-containing protein. (338 aa)
	LIN7C	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (220 aa)
	TANC1	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1863 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1113 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2161 aa)
	NETO1	Neuropilin and tolloid like 1. (533 aa)
	LRFN4	Uncharacterized protein. (677 aa)
	LRRC4C	Leucine rich repeat containing 4C. (637 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (527 aa)
	K7FU52_PELSI	Uncharacterized protein. (1329 aa)
	SAMD3	Sterile alpha motif domain containing 3. (524 aa)
	ABHD17C	Abhydrolase domain containing 17C. (311 aa)
	DBNL	Drebrin like. (411 aa)
	LOC102463966	Uncharacterized protein. (1286 aa)
	CACNA1C	Uncharacterized protein. (477 aa)
	TMEM108	Transmembrane protein 108. (443 aa)
	GRIP2	Glutamate receptor interacting protein 2. (564 aa)
	LRFN5	Leucine rich repeat and fibronectin type III domain containing 5. (704 aa)
	K7FNA0_PELSI	Uncharacterized protein. (111 aa)
	HOMER3	WH1 domain-containing protein. (354 aa)
	LRFN3	Leucine rich repeat and fibronectin type III domain containing 3. (651 aa)
	K7FME6_PELSI	Uncharacterized protein. (617 aa)
	HOMER1	Homer scaffold protein 1. (367 aa)
	SYT11	Synaptotagmin 11. (373 aa)
	CHAD	Uncharacterized protein. (361 aa)
	RGS7BP	Regulator of G protein signaling 7 binding protein. (248 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1070 aa)
	PLPPR4	Phospholipid phosphatase related 4. (675 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF9	GPHN	ENSPSIP00000007716	ENSPSIP00000018826	Cdc42 guanine nucleotide exchange factor 9.	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	0.691
CACNA1C	CACNA1D	ENSPSIP00000010953	ENSPSIP00000003482	Uncharacterized protein.	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	0.900
CACNA1C	K7FUC6_PELSI	ENSPSIP00000010953	ENSPSIP00000011636	Uncharacterized protein.	Ca_chan_IQ domain-containing protein.	0.449
CACNA1D	CACNA1C	ENSPSIP00000003482	ENSPSIP00000010953	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	Uncharacterized protein.	0.900
CHAD	LOC102452389	ENSPSIP00000008521	ENSPSIP00000005860	Uncharacterized protein.	Fibronectin type-III domain-containing protein.	0.908
DBNL	HOMER2	ENSPSIP00000011303	ENSPSIP00000007314	Drebrin like.	Homer scaffold protein 2.	0.592
GPHN	ARHGEF9	ENSPSIP00000018826	ENSPSIP00000007716	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Cdc42 guanine nucleotide exchange factor 9.	0.691
GPHN	HOMER1	ENSPSIP00000018826	ENSPSIP00000008854	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Homer scaffold protein 1.	0.532
GRASP	MAGI2	ENSPSIP00000020328	ENSPSIP00000003837	General receptor for phosphoinositides 1 associated scaffold protein.	Membrane associated guanylate kinase, WW and PDZ domain containing 2.	0.453
GRIP1	GRIP2	ENSPSIP00000017271	ENSPSIP00000009916	Glutamate receptor interacting protein 1.	Glutamate receptor interacting protein 2.	0.612
GRIP2	GRIP1	ENSPSIP00000009916	ENSPSIP00000017271	Glutamate receptor interacting protein 2.	Glutamate receptor interacting protein 1.	0.612
HOMER1	GPHN	ENSPSIP00000008854	ENSPSIP00000018826	Homer scaffold protein 1.	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	0.532
HOMER1	HOMER2	ENSPSIP00000008854	ENSPSIP00000007314	Homer scaffold protein 1.	Homer scaffold protein 2.	0.925
HOMER1	HOMER3	ENSPSIP00000008854	ENSPSIP00000009354	Homer scaffold protein 1.	WH1 domain-containing protein.	0.987
HOMER1	K7FAF2_PELSI	ENSPSIP00000008854	ENSPSIP00000005012	Homer scaffold protein 1.	ANK_REP_REGION domain-containing protein.	0.665
HOMER1	K7FME6_PELSI	ENSPSIP00000008854	ENSPSIP00000009206	Homer scaffold protein 1.	Uncharacterized protein.	0.665
HOMER1	K7GCA4_PELSI	ENSPSIP00000008854	ENSPSIP00000017915	Homer scaffold protein 1.	PDZ domain-containing protein.	0.457
HOMER1	LOC102461662	ENSPSIP00000008854	ENSPSIP00000017926	Homer scaffold protein 1.	Uncharacterized protein.	0.832
HOMER1	SHANK2	ENSPSIP00000008854	ENSPSIP00000005965	Homer scaffold protein 1.	SAM domain-containing protein.	0.457
HOMER2	DBNL	ENSPSIP00000007314	ENSPSIP00000011303	Homer scaffold protein 2.	Drebrin like.	0.592