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U7PWP3_SPOS1 | Uncharacterized protein. (217 aa) | ||||
U7PVY0_SPOS1 | DUF2428 domain-containing protein. (1586 aa) | ||||
LSM3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (92 aa) | ||||
U7PVL2_SPOS1 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. (787 aa) | ||||
U7PUL5_SPOS1 | Uncharacterized protein. (127 aa) | ||||
U7PUB8_SPOS1 | Uncharacterized protein. (356 aa) | ||||
U7PU94_SPOS1 | PPM-type phosphatase domain-containing protein. (650 aa) | ||||
U7PU07_SPOS1 | DPH-type MB domain-containing protein. (210 aa) | ||||
TRM82 | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (588 aa) | ||||
U7PTC3_SPOS1 | Uncharacterized protein. (445 aa) | ||||
U7PT78_SPOS1 | Uncharacterized protein. (416 aa) | ||||
U7PT16_SPOS1 | Uncharacterized protein. (456 aa) | ||||
U7PSJ9_SPOS1 | Uncharacterized protein. (532 aa) | ||||
U7PS44_SPOS1 | TYW3 domain-containing protein. (377 aa) | ||||
U7PRY4_SPOS1 | Uncharacterized protein. (942 aa) | ||||
U7PRT4_SPOS1 | Sm domain-containing protein. (216 aa) | ||||
U7PRI2_SPOS1 | Uncharacterized protein. (561 aa) | ||||
U7PRH8_SPOS1 | Uncharacterized protein. (281 aa) | ||||
U7PRD1_SPOS1 | CMP/dCMP-type deaminase domain-containing protein. (494 aa) | ||||
U7PR86_SPOS1 | Uncharacterized protein. (1053 aa) | ||||
U7PR18_SPOS1 | Uncharacterized protein. (242 aa) | ||||
U7PR15_SPOS1 | PseudoU_synth_2 domain-containing protein. (589 aa) | ||||
U7PQY7_SPOS1 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA. (721 aa) | ||||
U7PQI1_SPOS1 | Uncharacterized protein. (370 aa) | ||||
U7PQ71_SPOS1 | Lysine-tRNA ligase. (660 aa) | ||||
U7PQ64_SPOS1 | Uncharacterized protein. (653 aa) | ||||
U7PPQ5_SPOS1 | Uncharacterized protein. (380 aa) | ||||
U7PPJ2_SPOS1 | Dextranase. (620 aa) | ||||
U7PP09_SPOS1 | Uncharacterized protein. (315 aa) | ||||
LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (159 aa) | ||||
U7PNY7_SPOS1 | Formyl_trans_N domain-containing protein. (495 aa) | ||||
U7PNW1_SPOS1 | Uncharacterized protein. (396 aa) | ||||
U7PNV2_SPOS1 | Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (674 aa) | ||||
U7PNR6_SPOS1 | tRNA pseudouridine(38-40) synthase. (641 aa) | ||||
U7PND8_SPOS1 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1340 aa) | ||||
U7PNB7_SPOS1 | SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (936 aa) | ||||
U7PN02_SPOS1 | tRNA pseudouridine(38-40) synthase. (568 aa) | ||||
U7PMY8_SPOS1 | Uncharacterized protein. (337 aa) | ||||
U7PMP6_SPOS1 | Alkylated DNA repair protein AlkB. (385 aa) | ||||
U7PME3_SPOS1 | Uncharacterized protein. (225 aa) | ||||
U7PM08_SPOS1 | Uncharacterized protein. (402 aa) | ||||
U7PLQ3_SPOS1 | Queuosine salvage protein; Involved in salvaging queuosine. (366 aa) | ||||
U7PLF9_SPOS1 | Uncharacterized protein. (270 aa) | ||||
uba4 | Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (489 aa) | ||||
U7PJT2_SPOS1 | Diphthamide biosynthesis protein 3. (86 aa) | ||||
U7PJS9_SPOS1 | tRNA-intron endonuclease. (616 aa) | ||||
URM1 | Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (110 aa) | ||||
U7PJC2_SPOS1 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. (194 aa) | ||||
U7PJA1_SPOS1 | Uncharacterized protein. (959 aa) | ||||
U7PHZ6_SPOS1 | tRNA modification GTPase TrmE. (552 aa) | ||||
U7PHE5_SPOS1 | SAM_MT_TRM5_TYW2 domain-containing protein. (506 aa) | ||||
U7Q8T1_SPOS1 | ATP_bind_3 domain-containing protein. (787 aa) | ||||
U7Q838_SPOS1 | Uncharacterized protein. (416 aa) | ||||
U7Q7U7_SPOS1 | Uncharacterized protein. (315 aa) | ||||
U7Q7R0_SPOS1 | THUMP domain-containing protein. (218 aa) | ||||
U7Q7J7_SPOS1 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. (536 aa) | ||||
U7Q7H2_SPOS1 | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (559 aa) | ||||
U7Q6H7_SPOS1 | DUF3453 domain-containing protein. (819 aa) | ||||
U7Q6E1_SPOS1 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (722 aa) | ||||
U7Q6B1_SPOS1 | Cysteine desulfurase, mitochondrial. (529 aa) | ||||
U7Q6A3_SPOS1 | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (467 aa) | ||||
U7Q5T0_SPOS1 | Sua5/YciO/YrdC/YwlC family protein. (463 aa) | ||||
U7Q5H8_SPOS1 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (386 aa) | ||||
U7Q5G3_SPOS1 | Uncharacterized protein. (691 aa) | ||||
TRM5 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (559 aa) | ||||
KAE1 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (401 aa) | ||||
ALA1 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (960 aa) | ||||
U7Q555_SPOS1 | Uncharacterized protein. (145 aa) | ||||
U7Q4Y2_SPOS1 | Uncharacterized protein. (342 aa) | ||||
U7Q4K7_SPOS1 | Uncharacterized protein. (497 aa) | ||||
U7Q4I1_SPOS1 | tRNA pseudouridine(55) synthase. (526 aa) | ||||
LSM5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (80 aa) | ||||
U7Q4D7_SPOS1 | RRM domain-containing protein. (914 aa) | ||||
U7Q493_SPOS1 | SAM-dependent MTase TRM10-type domain-containing protein. (459 aa) | ||||
NAT10 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1164 aa) | ||||
U7Q3R8_SPOS1 | tRNA_SAD domain-containing protein. (315 aa) | ||||
U7Q3I6_SPOS1 | U6 snRNA-associated Sm-like protein LSm6. (84 aa) | ||||
U7Q367_SPOS1 | Uncharacterized protein. (408 aa) | ||||
U7Q340_SPOS1 | Uncharacterized protein. (269 aa) | ||||
U7Q2X1_SPOS1 | Uncharacterized protein. (284 aa) | ||||
U7Q2Q3_SPOS1 | tRNA ligase. (844 aa) | ||||
U7Q2E5_SPOS1 | Uncharacterized protein. (529 aa) | ||||
U7Q274_SPOS1 | tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (297 aa) | ||||
U7Q1V8_SPOS1 | Uncharacterized protein. (355 aa) | ||||
U7Q1L3_SPOS1 | Ribonuclease P protein subunit. (304 aa) | ||||
U7Q1A8_SPOS1 | Uncharacterized protein. (303 aa) | ||||
U7Q166_SPOS1 | BUD32 protein kinase. (307 aa) | ||||
AIM41 | Altered inheritance of mitochondria protein 41. (201 aa) | ||||
U7Q127_SPOS1 | Flavodoxin-like domain-containing protein. (888 aa) | ||||
U7Q109_SPOS1 | tRNA_int_endo domain-containing protein. (446 aa) | ||||
U7Q0X4_SPOS1 | Uncharacterized protein. (494 aa) | ||||
U7Q0V7_SPOS1 | Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1071 aa) | ||||
U7Q0N1_SPOS1 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (111 aa) | ||||
U7Q0L7_SPOS1 | UPF0020 domain-containing protein. (518 aa) | ||||
U7Q0G9_SPOS1 | Sen15 domain-containing protein. (192 aa) | ||||
U7Q0B3_SPOS1 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (579 aa) | ||||
U7PZT4_SPOS1 | ThiF domain-containing protein. (600 aa) | ||||
U7PZS3_SPOS1 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (375 aa) | ||||
TRM8 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (316 aa) | ||||
U7PZD3_SPOS1 | YrdC-like domain-containing protein. (242 aa) | ||||
U7PYR1_SPOS1 | Uncharacterized protein. (609 aa) | ||||
U7PYN2_SPOS1 | Methyltransf_25 domain-containing protein. (367 aa) | ||||
U7PYD4_SPOS1 | TRUD domain-containing protein. (882 aa) | ||||
U7PYD3_SPOS1 | tRNA_int_end_N2 domain-containing protein. (675 aa) | ||||
U7PY83_SPOS1 | WD_REPEATS_REGION domain-containing protein. (1377 aa) | ||||
U7PXW2_SPOS1 | A to I editase domain-containing protein. (413 aa) | ||||
U7PXS7_SPOS1 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (310 aa) | ||||
U7PXD5_SPOS1 | Uncharacterized protein. (342 aa) | ||||
NCS6 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (445 aa) |