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fbaA fbaA gapA gapA pgk pgk gpmA gpmA Epro_0239 Epro_0239 pfkA pfkA tyrS tyrS Epro_0242 Epro_0242 Epro_0243 Epro_0243 tpiA tpiA rpiB rpiB Epro_0249 Epro_0249 Epro_0250 Epro_0250 Epro_0251 Epro_0251 Epro_0252 Epro_0252 tktB tktB tkt tkt Epro_0255 Epro_0255 deoB deoB punA punA deoA deoA recJ recJ cdd cdd Epro_0261 Epro_0261 nudF nudF pfkA-2 pfkA-2 pykF pykF rpe rpe eno eno prsA-2 prsA-2 pgi pgi
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbaAFructose-bisphosphate aldolase. (331 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
gpmAPhosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
Epro_0239Putative U32 family peptidase. (658 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (382 aa)
Epro_0242Putative lipoprotein. (203 aa)
Epro_0243Conserved exported protein of unknown function. (483 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
rpiBRibose 5-phosphate epimerase. (153 aa)
Epro_0249Exported protein of unknown function. (143 aa)
Epro_0250Exported protein of unknown function. (202 aa)
Epro_0251Conserved exported protein of unknown function. (447 aa)
Epro_0252Exported protein of unknown function. (581 aa)
tktBPutative transketolase N-terminal section. (275 aa)
tktPutative transketolase C-terminal section. (315 aa)
Epro_0255Hypothetical protein. (45 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (393 aa)
punAPurine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (267 aa)
deoAThymidine phosphorylase. (438 aa)
recJPutative Single-stranded-DNA-specific exonuclease RecJ. (674 aa)
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (127 aa)
Epro_0261Putative Na/Pi-cotransporter II-related protein. (555 aa)
nudFADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family. (175 aa)
pfkA-2Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta 2; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (557 aa)
pykFPyruvate kinase; Belongs to the pyruvate kinase family. (341 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (215 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)
prsA-2Phosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa)
pgiGlucosephosphate isomerase; Belongs to the GPI family. (547 aa)
Your Current Organism:
Endomicrobium proavitum
NCBI taxonomy Id: 1408281
Other names: Candidatus Endomicrobium sp. Rsa215, DSM 29378, E. proavitum, Endomicrobium proavitum Zheng et al. 2018, JCM 30189, JCM 32103, strain Rsa215
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