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ribBA ribBA coaD coaD BN938_0272 BN938_0272 nadD nadD BN938_0965 BN938_0965 BN938_1117 BN938_1117 BN938_1173 BN938_1173 BN938_1418 BN938_1418 folE folE dut dut BN938_1609 BN938_1609 nadA nadA asnA asnA BN938_1980 BN938_1980 panB panB coaE coaE BN938_2135 BN938_2135 BN938_2357 BN938_2357 BN938_2375 BN938_2375 panD panD panC panC BN938_2761 BN938_2761 BN938_2876 BN938_2876 BN938_2893 BN938_2893 BN938_2944 BN938_2944 BN938_2979 BN938_2979 ribH ribH nadK nadK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ribBA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (406 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (155 aa)
BN938_0272Oxygen-insensitive NADPH nitroreductase; Belongs to the flavin oxidoreductase frp family. (248 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (247 aa)
BN938_0965Aspartate ammonia-lyase. (477 aa)
BN938_1117Riboflavin synthase eubacterial/eukaryotic. (198 aa)
BN938_11732-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase. (155 aa)
BN938_1418NAD-dependent protein deacetylase of SIR2 family. (232 aa)
folEGTP cyclohydrolase I type 1. (189 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
BN938_1609L-asparaginase. (336 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (304 aa)
asnAAspartate--ammonia ligase. (334 aa)
BN938_1980Riboflavin kinase. (229 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (194 aa)
BN938_2135L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (549 aa)
BN938_2357C-terminal domain of CinA type S; Belongs to the CinA family. (423 aa)
BN938_2375Dihydropteroate synthase. (268 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (117 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (271 aa)
BN938_2761Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa)
BN938_2876Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (122 aa)
BN938_2893Quinolinate phosphoribosyltransferase [decarboxylating]; Belongs to the NadC/ModD family. (283 aa)
BN938_2944NAD synthetase / Glutamine amidotransferase chain of NAD synthetase. (464 aa)
BN938_2979Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (352 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (200 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (279 aa)
Your Current Organism:
Mucinivorans hirudinis
NCBI taxonomy Id: 1433126
Other names: ATCC BAA-2553, DSM 27344, M. hirudinis, Mucinivorans hirudinis Nelson et al. 2015, Rikenellaceae bacterium M3, Rikenellaceae bacterium M4, Rikenellaceae bacterium M6, strain M3
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