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| | SCL29780.1 | Hydrogenase maturation protein, carbamoyl dehydratase HypE. (383 aa) |
| | SCL29776.1 | Hydrogenase expression/formation protein HypD. (375 aa) |
| | SCL29768.1 | Hydrogenase expression/formation protein HypC. (90 aa) |
| | hypA | Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (118 aa) |
| | SCL29699.1 | RNA polymerase sigma-70 factor, ECF subfamily. (163 aa) |
| | SCL29421.1 | RNA polymerase sigma-70 factor, ECF subfamily. (182 aa) |
| | SCL29073.1 | Hypothetical protein. (249 aa) |
| | SCL28763.1 | Hypothetical protein. (494 aa) |
| | SCL28757.1 | Hypothetical protein. (268 aa) |
| | SCL27920.1 | RNA polymerase sigma factor, sigma-70 family. (289 aa) |
| | smpB | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (168 aa) |
| | SCL27682.1 | RNA polymerase sigma-70 factor, ECF subfamily. (172 aa) |
| | rtcB-2 | Release factor H-coupled RctB family protein; Belongs to the RtcB family. (400 aa) |
| | SCL26736.1 | Peptide chain release factor. (235 aa) |
| | SCL25745.1 | P-aminobenzoate N-oxygenase AurF. (360 aa) |
| | SCL24526.1 | tRNA-splicing ligase RtcB. (399 aa) |
| | SCL24410.1 | RNA polymerase sigma-70 factor, ECF subfamily. (208 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (168 aa) |
| | SCL24019.1 | Selenocysteine-specific elongation factor. (586 aa) |
| | selA | L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (430 aa) |
| | SCL23890.1 | SHS2 domain-containing protein. (131 aa) |
| | rtcB | tRNA-splicing ligase RtcB; Belongs to the RtcB family. (472 aa) |
| | kptA | Putative RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (175 aa) |
| | SCL23328.1 | tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Belongs to the SUA5 family. (210 aa) |
| | SCL22963.1 | Tripartite tricarboxylate transporter TctB family protein. (215 aa) |
| | SCL22442.1 | tRNA (adenine-58-N(1)-) methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (338 aa) |
| | SCL22106.1 | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. (380 aa) |
| | SCL21591.1 | Protein of unknown function. (285 aa) |
| | SCL21198.1 | RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. (414 aa) |
| | SCL21139.1 | Hypothetical protein. (346 aa) |
| | SCL21075.1 | Hypothetical protein. (643 aa) |
| | SCL20734.1 | P-aminobenzoate N-oxygenase AurF. (319 aa) |
| | SCL20634.1 | Hypothetical protein. (225 aa) |
| | SCL19855.1 | Hypothetical protein. (264 aa) |
| | SCL19572.1 | tRNA G18 (ribose-2'-O)-methylase SpoU. (269 aa) |
| | SCL19234.1 | ATPase components of ABC transporters with duplicated ATPase domains. (535 aa) |
| | SCL19194.1 | Hypothetical protein. (209 aa) |
| | SCL18938.1 | GTP-binding protein. (622 aa) |
| | SCL18881.1 | SSU ribosomal protein S1P. (495 aa) |
| | SCL18522.1 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (313 aa) |
| | rsmH | 16S rRNA (cytosine1402-N4)-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (370 aa) |
| | leuS | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (944 aa) |
| | SCL17960.1 | tRNA 2-thiouridine synthesizing protein A; Belongs to the sulfur carrier protein TusA family. (85 aa) |
| | lipB | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (213 aa) |
| | aspS | Nondiscriminating aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. (428 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (328 aa) |
| | SCL17776.1 | RNA polymerase sigma-70 factor, sigma-E family; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa) |
| | SCL17773.1 | Hypothetical protein. (450 aa) |
| | SCL17500.1 | RNA polymerase sigma-70 factor, sigma-E family; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (465 aa) |
| | SCL17217.1 | seryl-tRNA synthetase. (429 aa) |
| | argS | arginyl-tRNA synthetase. (572 aa) |
| | SCL16518.1 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (611 aa) |
| | rplP | LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (141 aa) |
| | rpsC | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (289 aa) |
| | rplV | LSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (152 aa) |
| | rpsS | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa) |
| | rplB | LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (279 aa) |
| | rplW | LSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplD | LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (221 aa) |
| | rplC | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (221 aa) |
| | rpsJ | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | tuf | Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa) |
| | fusA | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (698 aa) |
| | rpsG | Small subunit ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | rpsL | SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1297 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1146 aa) |
| | rplL | LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (127 aa) |
| | rplJ | LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (181 aa) |
| | rplA | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (238 aa) |
| | rplK | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (143 aa) |
| | nusG | Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (240 aa) |
| | rpmG | LSU ribosomal protein L33P; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | SCL40642.1 | RNA polymerase sigma-70 factor, ECF subfamily. (188 aa) |
| | SCL40579.1 | RNA polymerase sigma-70 factor, sigma-E family; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa) |
| | SCL40483.1 | RNA polymerase sigma-70 factor, ECF subfamily. (317 aa) |
| | SCL40310.1 | RNA polymerase sigma-70 factor, ECF subfamily. (306 aa) |
| | SCL40265.1 | Leader peptidase (prepilin peptidase) / N-methyltransferase. (245 aa) |
| | SCL40239.1 | Gas vesicle synthesis protein GvpL/GvpF. (251 aa) |
| | SCL40212.1 | Lipopolysaccharide kinase (Kdo/WaaP) family protein. (402 aa) |
| | SCL40184.1 | 23S rRNA (guanosine2251-2'-O)-methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (371 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (471 aa) |
| | SCL40123.1 | Hypothetical protein. (320 aa) |
| | SCL40114.1 | Transcriptional regulator, CarD family. (161 aa) |
| | def-5 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (186 aa) |
| | lysS | lysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family. (502 aa) |
| | SCL39996.1 | Hypothetical protein. (186 aa) |
| | tilS | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (343 aa) |
| | SCL39733.1 | Hypothetical protein. (203 aa) |
| | tadA | tRNA(adenine34) deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (225 aa) |
| | SCL39666.1 | Hypothetical protein. (102 aa) |
| | SCL39660.1 | tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (352 aa) |
| | SCL39657.1 | Queuine tRNA-ribosyltransferase. (385 aa) |
| | SCL39654.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase; Specifically methylates the N7 position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides. (284 aa) |
| | SCL39639.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase; Specifically methylates the N7 position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides. (274 aa) |
| | rsmI | 16S rRNA (cytidine1402-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (291 aa) |
| | SCL39535.1 | RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (225 aa) |
| | SCL39411.1 | ATPase components of ABC transporters with duplicated ATPase domains. (550 aa) |
| | SCL39311.1 | RNA polymerase sigma-70 factor, sigma-E family; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa) |
| | SCL39254.1 | Methyltransferase domain-containing protein. (237 aa) |
| | rplI | LSU ribosomal protein L9P; Binds to the 23S rRNA. (149 aa) |
| | rpsR | SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (79 aa) |
| | rpsF | Small subunit ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (96 aa) |
| | SCL38788.1 | RNA polymerase sigma-70 factor, sigma-E family; Belongs to the sigma-70 factor family. ECF subfamily. (173 aa) |
| | SCL38786.1 | Hypothetical protein. (367 aa) |
| | SCL38764.1 | poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (486 aa) |
| | SCL38756.1 | RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (258 aa) |
| | rsmG | 16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (290 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (138 aa) |
| | rpmH | LSU ribosomal protein L34P; Belongs to the bacterial ribosomal protein bL34 family. (45 aa) |
| | SCL38686.1 | DNA gyrase subunit A. (1258 aa) |
| | proS-2 | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (588 aa) |
| | SCL38227.1 | RNA polymerase sigma-70 factor, sigma-E family; Belongs to the sigma-70 factor family. ECF subfamily. (172 aa) |
| | SCL38009.1 | Leader peptidase (prepilin peptidase) / N-methyltransferase; Belongs to the peptidase A24 family. (254 aa) |
| | SCL37994.1 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (328 aa) |
| | SCL37967.1 | RNA polymerase sigma factor, sigma-70 family. (381 aa) |
| | SCL37794.1 | Hypothetical protein. (124 aa) |
| | SCL37657.1 | RNA polymerase sigma-70 factor, ECF subfamily. (160 aa) |
| | SCL37583.1 | RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (350 aa) |
| | SCL37472.1 | Protein N-acetyltransferase, RimJ/RimL family. (214 aa) |
| | SCL37170.1 | RNA polymerase sigma factor, sigma-70 family. (427 aa) |
| | SCL37129.1 | Methyltransferase domain-containing protein. (248 aa) |
| | SCL37024.1 | Allophanate hydrolase. (571 aa) |
| | SCL37015.1 | Amidase. (655 aa) |
| | SCL36771.1 | Hypothetical protein. (475 aa) |
| | SCL36736.1 | Transcriptional regulator, PaaX family. (272 aa) |
| | SCL36593.1 | tRNA G18 (ribose-2'-O)-methylase SpoU. (207 aa) |
| | SCL36577.1 | RNA polymerase sigma-70 factor, sigma-E family; Belongs to the sigma-70 factor family. ECF subfamily. (237 aa) |
| | SCL42091.1 | Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (383 aa) |
| | glyQS | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (459 aa) |
| | ybeY | Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (157 aa) |
| | SCL42016.1 | 16S rRNA (uracil1498-N3)-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (244 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (622 aa) |
| | rpsT | SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. (88 aa) |
| | rpmA | LSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | rplU | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (104 aa) |
| | SCL41942.1 | Ribonuclease E. (1027 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1061 aa) |
| | valS-2 | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (872 aa) |
| | SCL41764.1 | Amidase; Belongs to the amidase family. (488 aa) |
| | SCL41738.1 | ATP-binding cassette protein, ChvD family. (558 aa) |
| | SCL41614.1 | RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (333 aa) |
| | SCL41541.1 | Hypothetical protein. (122 aa) |
| | SCL41503.1 | Hypothetical protein. (108 aa) |
| | SCL41445.1 | tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Belongs to the SUA5 family. (213 aa) |
| | prfA | Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (362 aa) |
| | rpmE | LSU ribosomal protein L31P; Binds the 23S rRNA. (74 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (676 aa) |
| | argS-2 | arginyl-tRNA synthetase. (555 aa) |
| | SCL41391.1 | 23S rRNA (adenine-N6)-dimethyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (267 aa) |
| | SCL41238.1 | RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (204 aa) |
| | SCL41132.1 | Hypothetical protein. (857 aa) |
| | SCL41080.1 | SAM-dependent methyltransferase. (243 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (854 aa) |
| | tsaD | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (348 aa) |
| | SCL40903.1 | Ribosomal-protein-alanine N-acetyltransferase. (197 aa) |
| | SCL40901.1 | tRNA threonylcarbamoyl adenosine modification protein YeaZ. (229 aa) |
| | SCL40891.1 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. (167 aa) |
| | rpsI | SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (154 aa) |
| | rplM | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa) |
| | SCL40812.1 | ATPase components of ABC transporters with duplicated ATPase domains. (559 aa) |
| | truA | tRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (276 aa) |
| | rplQ | LSU ribosomal protein L17P. (185 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (340 aa) |
| | rpsD | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (208 aa) |
| | rpsK | SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (135 aa) |
| | rpsM | SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (126 aa) |
| | rpmJ | LSU ribosomal protein L36P; Belongs to the bacterial ribosomal protein bL36 family. (37 aa) |
| | infA | Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa) |
| | rplO | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (147 aa) |
| | rpmD | LSU ribosomal protein L30P. (60 aa) |
| | rpsE | SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (204 aa) |
| | rplR | LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (129 aa) |
| | rplF | LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (180 aa) |
| | rpsH | SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (135 aa) |
| | rpsZ | SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) |
| | rplE | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (189 aa) |
| | rplX | LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (106 aa) |
| | rplN | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rpsQ | SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (93 aa) |
| | rpmC | LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (78 aa) |
| | SCL36509.1 | Hypothetical protein. (831 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (600 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (290 aa) |
| | rplY | LSU ribosomal protein L25P; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (227 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (196 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (341 aa) |
| | SCL36094.1 | threonyl-tRNA synthetase. (399 aa) |
| | SCL36002.1 | RNA polymerase sigma-70 factor, ECF subfamily. (166 aa) |
| | rnz | RNAse Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (308 aa) |
| | SCL35609.1 | Amidase. (467 aa) |
| | prfB | Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (373 aa) |
| | smpB-2 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (159 aa) |
| | SCL34675.1 | Ribonuclease BN, tRNA processing enzyme. (249 aa) |
| | rph | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (241 aa) |
| | SCL34611.1 | RNA polymerase sigma-70 factor, ECF subfamily. (206 aa) |
| | SCL34395.1 | Hypothetical protein. (406 aa) |
| | SCL34325.1 | Phospholipase_D-nuclease N-terminal. (145 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (351 aa) |
| | gatC | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (101 aa) |
| | gatA | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (491 aa) |
| | gatB | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (497 aa) |
| | SCL34156.1 | Hypothetical protein. (134 aa) |
| | SCL34084.1 | Ribosome-associated protein. (141 aa) |
| | rpmB | LSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family. (63 aa) |
| | SCL33955.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. (187 aa) |
| | rpmF | Large subunit ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (57 aa) |
| | rnc | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (317 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (468 aa) |
| | rpsP | SSU ribosomal protein S16P; Belongs to the bacterial ribosomal protein bS16 family. (147 aa) |
| | rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (184 aa) |
| | trmD | tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (256 aa) |
| | rplS | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (118 aa) |
| | SCL33826.1 | Signal peptidase I; Belongs to the peptidase S26 family. (290 aa) |
| | SCL33822.1 | Signal peptidase I; Belongs to the peptidase S26 family. (210 aa) |
| | rpsB | SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (284 aa) |
| | tsf | Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (275 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | rlmN | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (383 aa) |
| | SCL33745.1 | Hypothetical protein. (459 aa) |
| | nusA | NusA antitermination factor; Participates in both transcription termination and antitermination. (347 aa) |
| | SCL33585.1 | Hypothetical protein. (120 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (608 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (159 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (294 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (790 aa) |
| | rnj | Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (562 aa) |
| | miaB | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (499 aa) |
| | miaA | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (301 aa) |
| | SCL33169.1 | RNA polymerase nonessential primary-like sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (339 aa) |
| | sigA | RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (534 aa) |
| | SCL33057.1 | tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (418 aa) |
| | SCL33053.1 | tRNA(His) 5'-end guanylyltransferase. (257 aa) |
| | SCL32334.1 | Hypothetical protein. (264 aa) |
| | SCL32290.1 | RNA polymerase sigma-70 factor, ECF subfamily. (310 aa) |
| | SCL31775.1 | ATP-dependent helicase HrpA. (1412 aa) |
| | trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (256 aa) |
| | SCL31585.1 | ATP-dependent helicase HrpB. (840 aa) |
| | SCL31557.1 | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Belongs to the sigma-70 factor family. (275 aa) |
| | SCL31202.1 | Protein of unknown function. (138 aa) |
| | SCL31133.1 | rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (499 aa) |
| | thrS | threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (666 aa) |
| | SCL30790.1 | histidyl-tRNA synthetase. (443 aa) |
| | aspS-2 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (601 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (892 aa) |
| | SCL30609.1 | Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (152 aa) |
| | efp | Translation initiation factor 5A precursor (eIF-5A) /translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa) |
| | nusB | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (144 aa) |
| | SCL30492.1 | Hypothetical protein. (105 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (87 aa) |
| | def-3 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (186 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (310 aa) |
| | rpmI | LSU ribosomal protein L35P; Belongs to the bacterial ribosomal protein bL35 family. (64 aa) |
| | rplT | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (130 aa) |
| | SCL30363.1 | RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (293 aa) |
| | pheS | phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (366 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (848 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (430 aa) |
| | SCL30099.1 | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. (256 aa) |
| | SCL29993.1 | Sigma-70, region 4. (270 aa) |
| | SCL29853.1 | Hypothetical protein. (260 aa) |
| | SCL29819.1 | RNA polymerase sigma-70 factor, ECF subfamily; Manually curated; Belongs to the sigma-70 factor family. (284 aa) |
| | SCL29799.1 | Hydrogenase expression/formation protein HypC. (86 aa) |
