(24 nodes) Two-component regulatory system, and Two-component sensor kinase, N-terminal network (Rhodoferax saidenbachensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APW41112.1	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
	APW44617.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
	APW41312.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
	APW41313.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
	APW41736.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	APW41737.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
	APW44725.1	Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)
	APW42436.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
	APW44785.1	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
	APW42731.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
	APW43014.1	DNA-binding response regulator; Transcriptional activator of tricarboxylate transport system genes; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	APW43015.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
	APW43208.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	APW43209.1	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
	APW43263.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
	APW43741.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
	APW43742.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
	APW44159.1	Nucleoid occlusion factor SlmA; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
	APW44160.1	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
	APW44161.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	APW44261.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	APW44262.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
	APW44495.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	APW44496.1	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)

Your Current Organism:

Rhodoferax saidenbachensis

NCBI taxonomy Id: 1484693
Other names: CCUG 57711, DSM 22694, R. saidenbachensis, Rhodoferax saidenbachensis Kaden et al. 2014, strain ED16

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APW41112.1	APW41313.1	RS694_00165	RS694_01300	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.640
APW41112.1	APW41736.1	RS694_00165	RS694_03650	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.628
APW41112.1	APW42436.1	RS694_00165	RS694_07705	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.569
APW41112.1	APW42731.1	RS694_00165	RS694_09435	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.561
APW41112.1	APW43014.1	RS694_00165	RS694_11030	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Transcriptional activator of tricarboxylate transport system genes; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.572
APW41112.1	APW43015.1	RS694_00165	RS694_11035	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
APW41112.1	APW43208.1	RS694_00165	RS694_12180	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
APW41112.1	APW43263.1	RS694_00165	RS694_12495	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.665
APW41112.1	APW43742.1	RS694_00165	RS694_15175	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.620
APW41112.1	APW44161.1	RS694_00165	RS694_17590	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542
APW41112.1	APW44261.1	RS694_00165	RS694_18165	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.632
APW41112.1	APW44495.1	RS694_00165	RS694_19540	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.588
APW41112.1	APW44617.1	RS694_00165	RS694_00170	Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
APW41312.1	APW41313.1	RS694_01295	RS694_01300	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.967
APW41312.1	APW41736.1	RS694_01295	RS694_03650	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.838
APW41312.1	APW42436.1	RS694_01295	RS694_07705	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.698
APW41312.1	APW42731.1	RS694_01295	RS694_09435	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.819
APW41312.1	APW43014.1	RS694_01295	RS694_11030	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Transcriptional activator of tricarboxylate transport system genes; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.769
APW41312.1	APW43208.1	RS694_01295	RS694_12180	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.846
APW41312.1	APW43263.1	RS694_01295	RS694_12495	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.834