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| | flgK-2 | Flagellar hook-associated. (668 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (452 aa) |
| | dps-3 | DNA-binding DPS protein; Pfam:pfam00210 Ferritin-like domain; Belongs to the Dps family. (157 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (336 aa) |
| | ALQ56154.1 | Oxidoreductase; Pfam:pfam03358 NADPH-dependent FMN reductase. (188 aa) |
| | ALQ56145.1 | Pfam:pfam04442 Cytochrome c oxidase assembly protein CtaG/Cox11. (176 aa) |
| | ALQ56142.1 | Transmembrane cytochrome oxidase associated protein. (164 aa) |
| | nfuA | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (191 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (262 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa) |
| | dsbD | Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (601 aa) |
| | zapA | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (101 aa) |
| | secB | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (162 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (155 aa) |
| | surA | Chaperone SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (431 aa) |
| | lptD | LPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (748 aa) |
| | hepA | RNA polymerase-associated protein RapA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (964 aa) |
| | ALQ55817.1 | Pfam:pfam11399 Protein of unknown function (DUF3192). (126 aa) |
| | pilT | Twitching motility protein PilT; Pfam:pfam00437 Type II/IV secretion system protein. (346 aa) |
| | icc | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (261 aa) |
| | parE | DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (629 aa) |
| | parC | DNA topoisomerase 4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (765 aa) |
| | ALQ55774.1 | Hypothetical protein; Pfam:pfam01103 Surface antigen. (572 aa) |
| | recQ | ATP-dependent DNA helicase RecQ; Pfam:pfam09382 RQC domain. (607 aa) |
| | ALQ55768.1 | Pfam:pfam04219 Protein of unknown function, DUF. (124 aa) |
| | srmB | ATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (408 aa) |
| | dps-2 | Stress response DNA-binding protein Dps; Pfam:pfam00210 Ferritin-like domain; Belongs to the Dps family. (174 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | ALQ55529.1 | Hypothetical protein. (274 aa) |
| | ALQ55528.1 | Hypothetical protein. (996 aa) |
| | flgN | Flagellar biosynthesis chaperone; Pfam:pfam05130 FlgN protein. (143 aa) |
| | flgM | Negative regulator of flagellin synthesis; Pfam:pfam04316 Anti-sigma-28 factor, FlgM. (106 aa) |
| | flgA-2 | Flagellar biosynthesis assembly of basal-body periplasmic P-ring; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (198 aa) |
| | flgD-2 | Flagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein. (225 aa) |
| | ALQ56852.1 | Hypothetical protein. (533 aa) |
| | ALQ56846.1 | Energy transducer TonB; Pfam:pfam11932 Protein of unknown function (DUF3450). (250 aa) |
| | minC | Putative septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (234 aa) |
| | minD | Site-determining protein; Pfam:pfam01656 CobQ/CobB/MinD/ParA nucleotide binding domain. (269 aa) |
| | ALQ56791.1 | Pfam:pfam11399 Protein of unknown function (DUF3192). (121 aa) |
| | pqiB | Putative paraquat-inducible protein B; Pfam:pfam02470 mce related protein. (551 aa) |
| | csgE | Curli production assembly/transport component; Pfam:pfam10627 Curli assembly protein CsgE. (130 aa) |
| | csgF | Putative curli production assembly/transport component; Pfam:pfam10614 Type VIII secretion system (T8SS), CsgF protein. (137 aa) |
| | csgG | Transporter; Pfam:pfam03783 Curli production assembly/transport component CsgG. (257 aa) |
| | bamB | Outer membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (392 aa) |
| | recQ-2 | ATP-dependent DNA helicase RecQ; Pfam:pfam00271 Helicase conserved C-terminal domain. (646 aa) |
| | iscS-2 | Cysteine desulfurase; Pfam:pfam00266 Aminotransferase class-V. (375 aa) |
| | ALQ56388.1 | Hypothetical protein. (530 aa) |
| | ALQ56382.1 | TPR repeat-containing protein; Pfam:pfam13414 TPR repeat. (294 aa) |
| | ALQ56340.1 | Hypothetical protein. (255 aa) |
| | ALQ56339.1 | Hypothetical protein; Pfam:pfam13620 Carboxypeptidase regulatory-like domain. (1072 aa) |
| | yaeJ | Peptidyl-tRNA hydrolase; Pfam:pfam00472 RF-1 domain. (137 aa) |
| | ALQ56298.1 | Helicase; Pfam:pfam00176 SNF2 family N-terminal domain. (1048 aa) |
| | ALQ56294.1 | Putative membrane protein insertion efficiency factor; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (91 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (808 aa) |
| | ALQ53360.1 | Calmodulin. (70 aa) |
| | ALQ53361.1 | Calmodulin. (70 aa) |
| | ALQ53362.1 | Calmodulin. (70 aa) |
| | ALQ53363.1 | Calmodulin. (71 aa) |
| | yrdD | Cytochrome C551; Pfam:pfam01396 Topoisomerase DNA binding C4 zinc finger. (191 aa) |
| | cyaY | Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (107 aa) |
| | uvrD | DNA-dependent helicase II; Pfam:pfam13361 UvrD-like helicase C-terminal domain. (721 aa) |
| | comM | Regulator; Pfam:pfam01078 Magnesium chelatase, subunit ChlI. (503 aa) |
| | typA | GTP-binding protein; Pfam:pfam00009 Elongation factor Tu GTP binding domain. (607 aa) |
| | rep | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (672 aa) |
| | engB | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (218 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (727 aa) |
| | pilM | Pfam:pfam11104 Type IV pilus assembly protein PilM. (359 aa) |
| | pilN | Type IV pilus biogenesis protein PilN; Pfam:pfam05137 Fimbrial assembly protein (PilN). (190 aa) |
| | pilO | Pfam:pfam04350 Pilus assembly protein, PilO. (200 aa) |
| | pilP | Pfam:pfam04351 Pilus assembly protein, PilP. (179 aa) |
| | lptA | ABC transporter substrate-binding protein; Pfam:pfam03968 OstA-like protein. (179 aa) |
| | lptC | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. (184 aa) |
| | mlaF | Pfam:pfam00005 ABC transporter. (271 aa) |
| | mlaC | ABC-type transport system, auxiliary component; Pfam:pfam05494 Toluene tolerance, Ttg2. (226 aa) |
| | mlaB | Anti-sigma B factor antagonist; Pfam:pfam01740 STAS domain. (97 aa) |
| | ALQ53753.1 | Transcriptional regulator; Pfam:pfam01722 BolA-like protein; Belongs to the BolA/IbaG family. (85 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa) |
| | iscS | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (405 aa) |
| | iscU | Scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (127 aa) |
| | iscA | Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. (107 aa) |
| | hscB | Cobalamin 5'-phosphate synthase; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (175 aa) |
| | hscA | Molecular chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa) |
| | aer | Chemotaxis protein; Pfam:pfam00015 Methyl-accepting chemotaxis protein (MCP) signalling domain. (513 aa) |
| | ftsI | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (605 aa) |
| | murE | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (494 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (462 aa) |
| | mraY | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (444 aa) |
| | ftsW | Putative lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (391 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (358 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (483 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (306 aa) |
| | ftsQ | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (259 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (414 aa) |
| | dps | DNA polymerase sliding clamp subunit; Pfam:pfam00210 Ferritin-like domain; Belongs to the Dps family. (174 aa) |
| | ALQ53947.1 | Putative QueD like protein; Pfam:pfam10881 Protein of unknown function (DUF2726). (198 aa) |
| | dnaB | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (459 aa) |
| | topB | DNA topoisomerase 3; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (646 aa) |
| | mltF | Murein transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (481 aa) |
| | bacA | UDP pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (266 aa) |
| | mpl | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (451 aa) |
| | ALQ54115.1 | Pfam:pfam07603 Protein of unknown function (DUF1566). (548 aa) |
| | ALQ54116.1 | Adhesin; Pfam:pfam07603 Protein of unknown function (DUF1566). (171 aa) |
| | mrcB | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (777 aa) |
| | erpA | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. (112 aa) |
| | ALQ54180.1 | Hypothetical protein. (140 aa) |
| | flgA | Flagellar basal body P-ring biosynthesis protein FlgA; Pfam:pfam13144 SAF-like. (253 aa) |
| | flgD | LfgD; Required for flagellar hook formation. May act as a scaffolding protein. (217 aa) |
| | flgJ | Putative flagellar protein; Pfam:pfam10135 Rod binding protein. (153 aa) |
| | flgK | Pfam:pfam06429 Flagellar basal body rod FlgEFG protein C-terminal. (435 aa) |
| | fliS | LafC; Pfam:pfam02561 Flagellar protein FliS. (128 aa) |
| | fliK | LafE; Pfam:pfam02120 Flagellar hook-length control protein FliK. (429 aa) |
| | fliP | Flagellar biosynthesis protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (250 aa) |
| | ALQ54208.1 | Flagellar biosynthetic protein FliQ; Pfam:pfam01313 Bacterial export proteins, family 3. (89 aa) |
| | fliR | Flagellar biosynthetic protein fliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (259 aa) |
| | flhB | Flagellar biosynthetic protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (376 aa) |
| | flhA | Lateral flagellar biosynthesis protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (691 aa) |
| | fliI | Putative FliI, flagellum-specific ATP synthase; Pfam:pfam00006 ATP synthase alpha/beta family, nucleotide-binding domain. (449 aa) |
| | murJ | Putative lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (526 aa) |
| | pilV | Type IV pilus biogenesis protein membrane protein. (186 aa) |
| | pilW | Prepilin-type cleavage/methylation-like protein. (332 aa) |
| | ALQ54288.1 | Hypothetical protein. (167 aa) |
| | pilE | Putative fimbrial protein. (139 aa) |
| | bamD | Outer membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (254 aa) |
| | aer-2 | Chemotaxis protein; Pfam:pfam00015 Methyl-accepting chemotaxis protein (MCP) signalling domain. (515 aa) |
| | ALQ54301.1 | Membrane protein; Pfam:pfam01578 Cytochrome C assembly protein. (268 aa) |
| | ALQ54368.1 | Secreted calmodulin-like protein. (70 aa) |
| | ALQ54369.1 | Secreted calmodulin-like protein. (70 aa) |
| | ALQ54370.1 | Secreted calmodulin-like protein. (71 aa) |
| | ALQ54429.1 | Hypothetical protein. (894 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa) |
| | ruvB | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (335 aa) |
| | cpoB | Prenyltransferase; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (232 aa) |
| | recC | Exonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoe [...] (1099 aa) |
| | recB | Exonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] (1188 aa) |
| | recD | Exonuclease V alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoe [...] (672 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1157 aa) |
| | mltG | ABC transporter substrate-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (328 aa) |
| | pilZ | Type 4 fimbrial biogenesis protein PILZ; Pfam:pfam07238 PilZ domain. (108 aa) |
| | ALQ54554.1 | Capsule biosynthesis protein CapC. (242 aa) |
| | ALQ54598.1 | Pfam:pfam04320 Protein with unknown function (DUF469). (108 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (902 aa) |
| | rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (120 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (899 aa) |
| | ALQ54732.1 | ATP-dependent RNA helicase, DEAD box; Pfam:pfam00270 DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (440 aa) |
| | sufE | SufE protein; Pfam:pfam02657 Fe-S metabolizm associated domain. (138 aa) |
| | zapC | Cell division protein ZapC; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (176 aa) |
| | mrp | MinD/MRP family ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (358 aa) |
| | bax | Putative glucosaminidase; Pfam:pfam01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase. (269 aa) |
| | helD | DNA helicase IV; Pfam:pfam00580 UvrD/REP helicase N-terminal domain. (707 aa) |
| | ALQ55023.1 | Hypothetical protein; Pfam:pfam02016 LD-carboxypeptidase. (352 aa) |
| | ALQ55074.1 | Pfam:pfam11932 Protein of unknown function (DUF3450). (256 aa) |
| | ALQ55118.1 | Metallo-beta-lactamase; Pfam:pfam00266 Aminotransferase class-V. (751 aa) |
| | mlaC-2 | ABC transporter ATP-binding protein; Pfam:pfam05494 Toluene tolerance, Ttg2. (197 aa) |
| | bamC | Outer membrane protein assembly factor BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (352 aa) |
| | zipA | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (248 aa) |
| | smc | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1133 aa) |
| | ALQ55199.1 | Pfam:pfam12695 Alpha/beta hydrolase family. (218 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (361 aa) |
| | lptE | Lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (163 aa) |
| | ybeB | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (105 aa) |
| | mrdA | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. (626 aa) |
| | rodA | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (368 aa) |
| | rlpA | Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (253 aa) |
| | dacC | Pfam:pfam00768 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (389 aa) |
| | priC | Pfam:pfam07445 Primosomal replication protein priB and priC. (202 aa) |
| | ALQ55304.1 | Hypothetical protein; Pfam:pfam00580 UvrD/REP helicase N-terminal domain. (614 aa) |
| | rlpA-2 | RlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (132 aa) |
| | hlpA | Pfam:pfam03938 Outer membrane protein (OmpH-like). (172 aa) |
| | bamA | Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (837 aa) |
| | uppS | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (259 aa) |
| | frr | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | yhbY | RNA binding protein; Pfam:pfam01985 CRS1 / YhbY (CRM) domain. (98 aa) |
| | bamE | Outer membrane protein assembly factor BamE; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (119 aa) |
| | mlaA | Lipoprotein; Pfam:pfam04333 VacJ like lipoprotein. (243 aa) |
| | ALQ55438.1 | Cytochrome C biogenesis protein; Pfam:pfam13414 TPR repeat. (418 aa) |
| | ccmH | Cytochrome c-type biogenesis protein CcmH; Possible subunit of a heme lyase. (153 aa) |
| | ccmG | Thiol:disulfide interchange protein dsbE (Cytochrome c biogenesis protein ccmG); Pfam:pfam08534 Redoxin. (190 aa) |
| | ccmF | Cytochrome c-type biogenesis protein CcmF; Pfam:pfam01578 Cytochrome C assembly protein. (653 aa) |
| | ccmE | Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (159 aa) |
| | ccmD | Heme exporter protein D (Cytochrome c-type biogenesis protein ccmD); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (67 aa) |
| | ccmC | Heme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (245 aa) |
| | ccmB | Heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (228 aa) |
| | ccmA | Cytochrome c biogenesis ATP-binding export protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (191 aa) |
| | ALQ55447.1 | Hypothetical protein; Pfam:pfam02120 Flagellar hook-length control protein FliK. (721 aa) |
| | flhF | Flagellar biosynthesis regulator FlhF; Pfam:pfam00448 SRP54-type protein, GTPase domain. (496 aa) |
| | flhA-2 | Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (702 aa) |
| | flhB-2 | Flagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (376 aa) |
| | fliR-2 | Flagellar biosynthetic protein fliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (259 aa) |
| | fliQ | Flagellar biosynthesis; Pfam:pfam01313 Bacterial export proteins, family 3. (89 aa) |
| | fliP-2 | Flagellar biosynthesis protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (246 aa) |
| | fliO | Pfam:pfam04347 Flagellar biosynthesis protein, FliO. (127 aa) |
| | fliK-2 | Pfam:pfam02120 Flagellar hook-length control protein FliK. (602 aa) |
| | fliJ | Pfam:pfam02050 Flagellar FliJ protein. (148 aa) |
| | fliI-2 | Pfam:pfam00006 ATP synthase alpha/beta family, nucleotide-binding domain. (444 aa) |
| | fliS-2 | Pfam:pfam02561 Flagellar protein FliS. (140 aa) |
| | flgJ-2 | Glucosaminidase; Pfam:pfam01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase. (331 aa) |
