STRINGSTRING
mraZ mraZ rsmH rsmH AIL64428.1 AIL64428.1 penA penA murE murE murC murC murG murG ftsW ftsW lpxC lpxC murA murA mreB mreB AIL64566.1 AIL64566.1 AIL64616.1 AIL64616.1 AIL64626.1 AIL64626.1 AIL64670.1 AIL64670.1 AIL64711.1 AIL64711.1 AIL64712.1 AIL64712.1 mrdB mrdB lolC lolC lolD lolD dacB dacB AIL64831.1 AIL64831.1 bamA bamA mmpA mmpA amiC amiC AIL64848.1 AIL64848.1 AIL64879.1 AIL64879.1 mraY mraY murF murF AIL64939.1 AIL64939.1 murD murD lpxK lpxK AIL64954.1 AIL64954.1 AIL64977.1 AIL64977.1 lysS lysS AIL64995.1 AIL64995.1 lpxA lpxA fabZ fabZ lpxD lpxD AIL65001.1 AIL65001.1 AIL65005.1 AIL65005.1 ddlB ddlB AIL65025.1 AIL65025.1 ftsA ftsA AIL65060.1 AIL65060.1 osmY osmY AIL65103.1 AIL65103.1 yceG yceG pbpD pbpD AIL65146.1 AIL65146.1 AIL65147.1 AIL65147.1 AIL65149.1 AIL65149.1 AIL65151.1 AIL65151.1 exbD exbD exbB exbB lptB lptB AIL65155.1 AIL65155.1 AIL65156.1 AIL65156.1 kdsD kdsD AIL65158.1 AIL65158.1 AIL65160.1 AIL65160.1 AIL65166.1 AIL65166.1 AIL65168.1 AIL65168.1 ctpB ctpB AIL65185.1 AIL65185.1 AIL65186.1 AIL65186.1 AIL65188.1 AIL65188.1 AIL65195.1 AIL65195.1 ftsZ ftsZ AIL65229.1 AIL65229.1 AIL65258.1 AIL65258.1 AIL65264.1 AIL65264.1 tolR tolR tolB tolB pal pal AIL65278.1 AIL65278.1 AIL65284.1 AIL65284.1 mltA mltA AIL65322.1 AIL65322.1 AIL65323.1 AIL65323.1 rlmE rlmE AIL65329.1 AIL65329.1 AIL65375.1 AIL65375.1 AIL65376.1 AIL65376.1 mrcA mrcA estB estB AIL65451.1 AIL65451.1 AIL65471.1 AIL65471.1 AIL65472.1 AIL65472.1 vanX vanX lptG lptG lptD lptD surA surA nlpD nlpD AIL65515.1 AIL65515.1 AIL65521.1 AIL65521.1 yfgL yfgL AIL65634.1 AIL65634.1 ycfH ycfH kdsA kdsA ybbD_2 ybbD_2 murJ murJ dacA dacA bamD bamD NlpD_2 NlpD_2 ctb ctb lnt lnt AIL65805.1 AIL65805.1 waaA waaA AIL65811.1 AIL65811.1 AIL65828.1 AIL65828.1 AIL65920.1 AIL65920.1 lpxB lpxB AIL65976.1 AIL65976.1 ftsI ftsI murB murB slt slt AIL66013.1 AIL66013.1 kdsB kdsB AIL66093.1 AIL66093.1 AIL66094.1 AIL66094.1 rnhB rnhB AIL66105.1 AIL66105.1 kefC kefC AIL66108.1 AIL66108.1 AIL66111.1 AIL66111.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mraZCell division protein MraZ; Belongs to the MraZ family. (156 aa)
rsmHRibosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa)
AIL64428.1Hypothetical protein. (135 aa)
penAPenicillin-binding protein 2. (569 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (487 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (365 aa)
ftsWCell division protein FtsW; Belongs to the SEDS family. (379 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (290 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (427 aa)
mreBRod shape-determining protein MreB. (346 aa)
AIL64566.1Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (288 aa)
AIL64616.1SAM-dependent methyltransferase. (255 aa)
AIL64626.1Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (210 aa)
AIL64670.1Sporulation related domain protein. (343 aa)
AIL64711.1Outer membrane protein (porin). (419 aa)
AIL64712.1Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (218 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (380 aa)
lolCLipoprotein-releasing system transmembrane protein LolC. (413 aa)
lolDLipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. (223 aa)
dacBD-alanyl-D-alanine carboxypeptidase dacB precursor. (455 aa)
AIL64831.1Outer membrane protein. (188 aa)
bamAOuter membrane protein omp85 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (771 aa)
mmpAMetalloprotease mmpA. (375 aa)
amiCN-acetylmuramoyl-L-alanine amidase AmiC precursor. (264 aa)
AIL64848.1Glycoside hydrolase family protein. (345 aa)
AIL64879.1Helix-turn-helix domain protein. (128 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (363 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (461 aa)
AIL64939.1Hypothetical protein. (82 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (471 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (325 aa)
AIL64954.1Hypothetical protein. (974 aa)
AIL64977.1Putative F0F1-ATPase subunit (ATPase_gene1). (94 aa)
lysSLysine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (519 aa)
AIL64995.1Uncharacterized protein conserved in bacteria. (270 aa)
lpxAAcyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (265 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (149 aa)
lpxDUDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (363 aa)
AIL65001.1Uncharacterized protein conserved in bacteria. (185 aa)
AIL65005.1Hypothetical protein. (1000 aa)
ddlBD-alanine--D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (321 aa)
AIL65025.1Cell division protein FtsQ; Essential cell division protein. (265 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (405 aa)
AIL65060.1Transcriptional regulatory protein. (225 aa)
osmYOsmotically-inducible protein Y precursor. (198 aa)
AIL65103.1Phasin family protein. (155 aa)
yceGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (339 aa)
pbpDPenicillin-binding protein 4 precursor. (635 aa)
AIL65146.1Uncharacterized protein conserved in bacteria. (169 aa)
AIL65147.1Lipid A biosynthesis lauroyl acyltransferase. (291 aa)
AIL65149.1Putative assembly protein. (901 aa)
AIL65151.1Periplasmic protein TonB. (307 aa)
exbDBiopolymer transport protein exbD. (149 aa)
exbBBiopolymer transport protein exbB. (239 aa)
lptBLipopolysaccharide export system ATP-binding protein LptB. (247 aa)
AIL65155.1Lipopolysaccharide transport periplasmic protein LptA. (175 aa)
AIL65156.1Hypothetical protein; Lipopolysaccharide-assembly, LptC-related. (197 aa)
kdsDArabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. (333 aa)
AIL65158.1Ribonuclease D. (177 aa)
AIL65160.1Septum formation initiator. (112 aa)
AIL65166.1Hypothetical protein. (147 aa)
AIL65168.1Divergent polysaccharide deacetylase. (303 aa)
ctpBCarboxy-terminal processing protease CtpA precursor; Belongs to the peptidase S41A family. (436 aa)
AIL65185.1Cobyrinic acid a,c-diamide synthase. (217 aa)
AIL65186.1Hypothetical protein; Domain of unknown function (DUF3576). (178 aa)
AIL65188.1Predicted secreted (periplasmic) protein (DUF2159). (165 aa)
AIL65195.1Outer membrane autotransporter barrel protein. (1017 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (478 aa)
AIL65229.1Lipopolysaccharide ABC transporter permease LptF. (358 aa)
AIL65258.1SmpA / OmlA family protein. (160 aa)
AIL65264.1Hypothetical protein; DUF218 domain. (203 aa)
tolRTol system periplasmic component TolR; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (282 aa)
tolBTranslocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (439 aa)
palMinor outer membrane protein Omp16; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (160 aa)
AIL65278.1Nucleotidyltransferase family protein. (255 aa)
AIL65284.1Tim44-like domain protein. (213 aa)
mltAMembrane-bound lytic murein transglycosylase A precursor. (359 aa)
AIL65322.1Hypothetical protein. (103 aa)
AIL65323.1Peptidase family M23. (134 aa)
rlmERibosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (231 aa)
AIL65329.1Protein of unknown function (DUF1022). (325 aa)
AIL65375.1Ankyrin repeat protein. (576 aa)
AIL65376.1Lipid A core - O-antigen ligase. (406 aa)
mrcAPenicillin-binding protein 1A. (788 aa)
estBCarboxylesterase 2. (215 aa)
AIL65451.1Zinc finger-like domain protein. (235 aa)
AIL65471.1Peptidase family M23. (134 aa)
AIL65472.1Hypothetical protein. (103 aa)
vanXD-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (253 aa)
lptGLipopolysaccharide export system permease protein lptG. (364 aa)
lptDLPS-assembly protein LptD precursor; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. (721 aa)
surAPeptidyl-prolyl cis-trans isomerase surA. (301 aa)
nlpDMurein hydrolase activator NlpD precursor. (272 aa)
AIL65515.1YGGT family protein. (96 aa)
AIL65521.1Serine/Threonine kinase. (683 aa)
yfgLOuter membrane assembly lipoprotein yfgL. (439 aa)
AIL65634.1Uncharacterized protein conserved in bacteria. (213 aa)
ycfHPutative deoxyribonuclease YcfH. (262 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (277 aa)
ybbD_2Glycoside hydrolase family protein. (384 aa)
murJMultidrug transporter MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (516 aa)
dacAD-alanyl-D-alanine carboxypeptidase dacA precursor; Belongs to the peptidase S11 family. (374 aa)
bamDOuter membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (258 aa)
NlpD_2M23 family peptidase. (354 aa)
ctbGroup 3 truncated hemoglobin ctb. (138 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (520 aa)
AIL65805.1Double-strand break repair protein AddB. (983 aa)
waaA3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (427 aa)
AIL65811.1Uncharacterized protein conserved in bacteria. (225 aa)
AIL65828.1Enterobactin exporter EntS. (390 aa)
AIL65920.1Uncharacterized protein conserved in bacteria. (207 aa)
lpxBLipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (389 aa)
AIL65976.1Hypothetical protein. (170 aa)
ftsIPeptidoglycan synthase FtsI precursor. (605 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (299 aa)
sltSoluble lytic murein transglycosylase precursor. (681 aa)
AIL66013.1Putative acetyltransferase. (328 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (249 aa)
AIL66093.1OmpA family protein. (291 aa)
AIL66094.1Outer membrane protein. (269 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (203 aa)
AIL66105.1Uncharacterized protein conserved in bacteria. (169 aa)
kefCGlutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (617 aa)
AIL66108.1Hypothetical protein; Contains full VWA domain of Cobalamin biosynthesis protein CobT. (234 aa)
AIL66111.1Cobalamin biosynthesis protein CobT. (231 aa)
Your Current Organism:
Rickettsiales bacterium Ac37b
NCBI taxonomy Id: 1528098
Other names: R. bacterium Ac37b
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