(45 nodes) Mixed, incl. Protein N-linked glycosylation, and Polyketide sugar unit biosynthesis network (Campylobacter sp. RM6137)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	xseA	Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (384 aa)
	ubiE	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (237 aa)
	ARR00032.1	Hypothetical protein. (257 aa)
	perR	Peroxide stress transcriptional regulator PerR; Pfam match to PF01475.15 FUR; Belongs to the Fur family. (136 aa)
	ARR00040.1	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like. (256 aa)
	pglK	Flippase; Pfam match to PF01943.13 Polysacc_synt. (500 aa)
	ARR00043.1	Glycosyltransferase, family 1; Pfam match to PF00534.16 Glycos_transf_1. (346 aa)
	pglH	Pfam match to PF00534.16 Glycos_transf_1. (344 aa)
	pglJ	Pfam matches to PF00534.16 Glycos_transf_1, and to PF13439.2 Glyco_transf_4. (373 aa)
	pglB	Undecaprenyl-diphosphooligosaccharide--protein glycotransferase; Pfam match to PF02516.10 STT3. (696 aa)
	pglA	N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase; Pfam matches to PF00534.16 Glycos_transf_1, and to PF13477.2 Glyco_trans_4_2. (371 aa)
	pglC	N,N'-diacetylbacilliosaminyl-1-phosphate transferase; Pfam match to PF02397.12 Bac_transf. (201 aa)
	pglD	UDP-4-amino-4, 6-dideoxy-alpha-D-N-acetyl-D-glucosamine N-acetyltransferase; Pfam match to PF00132.20 Hexapep. (194 aa)
	xseB	Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (62 aa)
	ARR01039.1	Putative phosphatase, HAD family; Pfam match to PF00702.22 Hydrolase. (208 aa)
	ARR01040.1	Glycosyltransferase, family 2; Pfam match to PF00483.19 NTP_transferase. (192 aa)
	ARR01041.1	SnoaL-like domain protein; Pfam match to PF12680.3 SnoaL_2. (114 aa)
	ARR01042.1	Hypothetical protein. (389 aa)
	ARR01043.1	Hypothetical protein. (113 aa)
	ARR01044.1	Putative capsular polysaccharide biosynthesis protein. (670 aa)
	cdtC1	Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.10 CDtoxinA. (245 aa)
	cdtB1	Cytolethal distending toxin, subunit CdtB; Pfam match to PF03372.19 Exo_endo_phos. (273 aa)
	cdtA1	Cytolethal distending toxin, subunit CdtA; Pfam match to PF03498.10 CDtoxinA. (226 aa)
	ARR01134.1	dTDP-6-deoxy-3,4-keto-hexulose isomerase; Pfam match to PF05523.7 FdtA. (139 aa)
	ARR01135.1	dTDP-6-deoxy-3,4-keto-hexulose isomerase; Pfam match to PF05523.7 FdtA. (130 aa)
	ARR01136.1	Aminotransferase, DegT/DnrJ/EryC1/StrS family; Pfam match to PF01041.13 DegT_DnrJ_EryC1; Belongs to the DegT/DnrJ/EryC1 family. (362 aa)
	ARR01137.1	Glycosyltransferase, family 2; Pfam match to PF00535.22 Glycos_transf_2. (275 aa)
	cdtC2	Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.10 CDtoxinA. (245 aa)
	cdtB2	Cytolethal distending toxin, subunit CdtB; Pfam match to PF03372.19 Exo_endo_phos. (273 aa)
	cdtA2	Cytolethal distending toxin, subunit CdtA; Pfam match to PF03498.10 CDtoxinA. (226 aa)
	ARR01141.1	Glycosyltransferase, family 2; Pfam match to PF00535.22 Glycos_transf_2. (316 aa)
	ARR01142.1	dTDP-glucose 4,6-dehydratase; Pfam match to PF16363.1 GDP_Man_Dehyd; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (336 aa)
	ARR01143.1	dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (288 aa)
	ARR01144.1	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (201 aa)
	ARR01145.1	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (294 aa)
	ARR01146.1	Acetyltransferase. (393 aa)
	ARR01147.1	L-ribulose-5-phosphate 4-epimerase; Pfam match to PF00596.17 Aldolase_II. (229 aa)
	ARR01148.1	UDP-glucuronate decarboxylase; Pfam match to PF01370.17 Epimerase. (349 aa)
	ispD	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Pfam match to PF01128.15 IspD. (232 aa)
	ARR01150.1	CDP-glycerol:glycerophosphate glycerophosphotransferase; Pfam match to PF04464.10 Glyphos_transf. (486 aa)
	ARR01151.1	Glycosyltransferase, family 1. (490 aa)
	ARR01160.1	Glycosyltransferase, family 2; Pfam match to PF00535.22 Glycos_transf_2. (316 aa)
	cdtA3	Cytolethal distending toxin, subunit CdtA; Pfam match to PF03498.10 CDtoxinA. (226 aa)
	cdtB3	Cytolethal distending toxin, subunit CdtB; Pfam match to PF03372.19 Exo_endo_phos. (273 aa)
	cdtC3	Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.10 CDtoxinA. (245 aa)

Your Current Organism:

Campylobacter sp. RM6137

NCBI taxonomy Id: 1660073
Other names: C. sp. RM6137

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARR00032.1	ARR00040.1	CSUIS_0185	CSUIS_0193	Hypothetical protein.	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	0.424
ARR00032.1	perR	CSUIS_0185	CSUIS_0186	Hypothetical protein.	Peroxide stress transcriptional regulator PerR; Pfam match to PF01475.15 FUR; Belongs to the Fur family.	0.548
ARR00032.1	ubiE	CSUIS_0185	CSUIS_0184	Hypothetical protein.	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).	0.773
ARR00032.1	xseA	CSUIS_0185	CSUIS_0183	Hypothetical protein.	Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.	0.773
ARR00040.1	ARR00032.1	CSUIS_0193	CSUIS_0185	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	Hypothetical protein.	0.424
ARR00040.1	ARR00043.1	CSUIS_0193	CSUIS_0196	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	Glycosyltransferase, family 1; Pfam match to PF00534.16 Glycos_transf_1.	0.430
ARR00040.1	perR	CSUIS_0193	CSUIS_0186	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	Peroxide stress transcriptional regulator PerR; Pfam match to PF01475.15 FUR; Belongs to the Fur family.	0.672
ARR00040.1	pglA	CSUIS_0193	CSUIS_0200	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase; Pfam matches to PF00534.16 Glycos_transf_1, and to PF13477.2 Glyco_trans_4_2.	0.430
ARR00040.1	pglB	CSUIS_0193	CSUIS_0199	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	Undecaprenyl-diphosphooligosaccharide--protein glycotransferase; Pfam match to PF02516.10 STT3.	0.579
ARR00040.1	pglC	CSUIS_0193	CSUIS_0201	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	N,N'-diacetylbacilliosaminyl-1-phosphate transferase; Pfam match to PF02397.12 Bac_transf.	0.430
ARR00040.1	pglD	CSUIS_0193	CSUIS_0202	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	UDP-4-amino-4, 6-dideoxy-alpha-D-N-acetyl-D-glucosamine N-acetyltransferase; Pfam match to PF00132.20 Hexapep.	0.430
ARR00040.1	pglH	CSUIS_0193	CSUIS_0197	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	Pfam match to PF00534.16 Glycos_transf_1.	0.430
ARR00040.1	pglJ	CSUIS_0193	CSUIS_0198	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	Pfam matches to PF00534.16 Glycos_transf_1, and to PF13439.2 Glyco_transf_4.	0.430
ARR00040.1	pglK	CSUIS_0193	CSUIS_0195	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	Flippase; Pfam match to PF01943.13 Polysacc_synt.	0.445
ARR00040.1	ubiE	CSUIS_0193	CSUIS_0184	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).	0.458
ARR00040.1	xseA	CSUIS_0193	CSUIS_0183	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.	0.459
ARR00043.1	ARR00040.1	CSUIS_0196	CSUIS_0193	Glycosyltransferase, family 1; Pfam match to PF00534.16 Glycos_transf_1.	HAD-superfamily hydrolase, subfamily IIA; Pfam matches to PF13344.2 Hydrolase_6, and to PF13242.2 Hydrolase_like.	0.430
ARR00043.1	ARR01142.1	CSUIS_0196	CSUIS_1349	Glycosyltransferase, family 1; Pfam match to PF00534.16 Glycos_transf_1.	dTDP-glucose 4,6-dehydratase; Pfam match to PF16363.1 GDP_Man_Dehyd; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.449
ARR00043.1	ARR01144.1	CSUIS_0196	CSUIS_1351	Glycosyltransferase, family 1; Pfam match to PF00534.16 Glycos_transf_1.	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	0.563
ARR00043.1	pglA	CSUIS_0196	CSUIS_0200	Glycosyltransferase, family 1; Pfam match to PF00534.16 Glycos_transf_1.	N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase; Pfam matches to PF00534.16 Glycos_transf_1, and to PF13477.2 Glyco_trans_4_2.	0.949