STRINGSTRING
mutM mutM OLF77896.1 OLF77896.1 OLF78013.1 OLF78013.1 OLF75421.1 OLF75421.1 nth nth ligA ligA OLF73954.1 OLF73954.1 OLF74166.1 OLF74166.1 OLF72996.1 OLF72996.1 OLF72250.1 OLF72250.1 OLF72400.1 OLF72400.1 OLF80831.1 OLF80831.1 OLF80835.1 OLF80835.1 polA polA OLF80579.1 OLF80579.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mutM5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (288 aa)
OLF77896.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (204 aa)
OLF78013.1single-stranded-DNA-specific exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
OLF75421.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (235 aa)
ligADNA ligase (NAD(+)) LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (701 aa)
OLF73954.13-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
OLF74166.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
OLF72996.1uracil-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
OLF72250.1uracil-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
OLF72400.1DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
OLF80831.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
OLF80835.1A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (355 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (928 aa)
OLF80579.13-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
Your Current Organism:
Maricaulis sp. W15
NCBI taxonomy Id: 1772333
Other names: M. sp. W15
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