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AMR80128.1 AMR80128.1 AMR76693.1 AMR76693.1 AMR76694.1 AMR76694.1 icmF icmF ackA ackA AMR80196.1 AMR80196.1 AMR77123.1 AMR77123.1 AMR77505.1 AMR77505.1 AMR77589.1 AMR77589.1 ackA-2 ackA-2 AMR78455.1 AMR78455.1 prpE prpE acsA acsA AMR79337.1 AMR79337.1 AMR79945.1 AMR79945.1 AMR80545.1 AMR80545.1 AMR81013.1 AMR81013.1 AMR81053.1 AMR81053.1 AMR81117.1 AMR81117.1 AMR81381.1 AMR81381.1 AMR81485.1 AMR81485.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMR80128.1Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
AMR76693.1Omega amino acid--pyruvate aminotransferase; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
AMR76694.1Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
icmFmethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1096 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (411 aa)
AMR80196.1Catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
AMR77123.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (478 aa)
AMR77505.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
AMR77589.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (377 aa)
AMR78455.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (477 aa)
prpECatalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
AMR79337.1Acyl CoA:acetate/3-ketoacid CoA transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (548 aa)
AMR79945.1NADPH:quinone dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AMR80545.1Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
AMR81013.1Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
AMR81053.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
AMR81117.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
AMR81381.1Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
AMR81485.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
Your Current Organism:
Cupriavidus nantongensis
NCBI taxonomy Id: 1796606
Other names: C. nantongensis, Cupriavidus nantongensis Sun et al. 2016, Cupriavidus sp. X1, KCTC 42909, LMG 29218, LMG:29218, strain X1
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