STRINGSTRING
tmk tmk APX71107.1 APX71107.1 pyrG pyrG APX71611.1 APX71611.1 APX71612.1 APX71612.1 APX71613.1 APX71613.1 APX71614.1 APX71614.1 APX71617.1 APX71617.1 APX72267.1 APX72267.1 APX72417.1 APX72417.1 APX72418.1 APX72418.1 gmk gmk APX72770.1 APX72770.1 tdk tdk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (216 aa)
APX71107.1dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (180 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (537 aa)
APX71611.1Class 1b ribonucleoside-diphosphate reductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
APX71612.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (721 aa)
APX71613.1Ribonucleotide reductase assembly protein NrdI; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NrdI family. (124 aa)
APX71614.1NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
APX71617.1Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
APX72267.1Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (747 aa)
APX72417.1Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (739 aa)
APX72418.1Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (193 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (203 aa)
APX72770.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (742 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
Your Current Organism:
Lactobacillus allii
NCBI taxonomy Id: 1847728
Other names: JCM 31938, KCTC 21077, L. allii, Lactobacillus allii Jung et al. 2017, Lactobacillus sp. WiKim39, strain WiKim39
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