STRINGSTRING
AIQ66326.1 AIQ66326.1 thiC thiC AIQ66702.1 AIQ66702.1 AIQ66707.1 AIQ66707.1 AIQ67876.1 AIQ67876.1 mqnC mqnC AIQ68060.1 AIQ68060.1 AIQ68061.1 AIQ68061.1 AIQ68062.1 AIQ68062.1 AIQ68063.1 AIQ68063.1 AIQ68064.1 AIQ68064.1 thiG thiG AIQ68066.1 AIQ68066.1 AIQ68127.1 AIQ68127.1 thiE thiE AIQ68612.1 AIQ68612.1 thiM thiM AIQ68944.1 AIQ68944.1 AIQ68945.1 AIQ68945.1 AIQ68946.1 AIQ68946.1 AIQ69295.1 AIQ69295.1 AIQ69296.1 AIQ69296.1 AIQ69812.1 AIQ69812.1 mqnA mqnA ubiX ubiX AIQ69815.1 AIQ69815.1 menG menG AIQ69817.1 AIQ69817.1 AIQ69818.1 AIQ69818.1 AIQ69819.1 AIQ69819.1 AIQ69820.1 AIQ69820.1 AIQ70856.1 AIQ70856.1 AIQ70857.1 AIQ70857.1 AIQ70858.1 AIQ70858.1 mqnE mqnE AIQ71462.1 AIQ71462.1 AIQ71474.1 AIQ71474.1 mqnB mqnB mqnD mqnD AIQ71747.1 AIQ71747.1 AIQ71748.1 AIQ71748.1 AIQ71749.1 AIQ71749.1 AIQ71750.1 AIQ71750.1 AIQ71751.1 AIQ71751.1 AIQ71752.1 AIQ71752.1 AIQ71753.1 AIQ71753.1 AIQ71755.1 AIQ71755.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIQ66326.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (564 aa)
AIQ66702.1Prenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family. (294 aa)
AIQ66707.1Heptaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (326 aa)
AIQ67876.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
mqnCRadical SAM protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (378 aa)
AIQ68060.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
AIQ68061.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
AIQ68062.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (61 aa)
AIQ68063.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
AIQ68064.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (254 aa)
AIQ68066.1Thiamine biosynthesis protein ThiH; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
AIQ68127.13-octaprenyl-4-hydroxybenzoate carboxy-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiD family. (621 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (218 aa)
AIQ68612.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (265 aa)
AIQ68944.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
AIQ68945.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
AIQ68946.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (62 aa)
AIQ69295.1Biotin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AIQ69296.1Thiamine biosynthesis protein ThiH; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
AIQ69812.1Heptaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (322 aa)
mqnAABC transporter substrate-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (286 aa)
ubiXAromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (200 aa)
AIQ69815.1Prenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family. (291 aa)
menGUbiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (248 aa)
AIQ69817.1Heptaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
AIQ69818.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
AIQ69819.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
AIQ69820.1DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
AIQ70856.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
AIQ70857.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
AIQ70858.1ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
mqnERadical SAM protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (368 aa)
AIQ71462.11,4-dihydroxy-2-naphthoate prenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AIQ71474.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
mqnBHypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (233 aa)
mqnD1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (279 aa)
AIQ71747.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (594 aa)
AIQ71748.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
AIQ71749.1ATP-binding/permease CydC; Derived by automated computational analysis using gene prediction method: Protein Homology. (587 aa)
AIQ71750.1Cytochrome d ubiquinol oxidase subunit 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AIQ71751.1Cytochrome D ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
AIQ71752.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
AIQ71753.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
AIQ71755.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
Your Current Organism:
Paenibacillus graminis
NCBI taxonomy Id: 189425
Other names: ATCC BAA-95, DSM 15220, LMG 19080, LMG:19080, P. graminis, Paenibacillus graminis Berge et al. 2002, Paenibacillus sp. RSA19, strain RSA19
Server load: medium (46%) [HD]