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bchU bchU gltX gltX hemN hemN cbiDJ cbiDJ cbiET cbiET cbiL cbiL CT0389 CT0389 cobA cobA CT0418 CT0418 CT0420 CT0420 CT0421 CT0421 CT0422 CT0422 cbiA-1 cbiA-1 cbiP cbiP cbiB cbiB btuR btuR cobP cobP cobT cobT cobS cobS CT1063 CT1063 CT1077 CT1077 chlG chlG bchH-3 bchH-3 bchD bchD bchI bchI bchR bchR CT1328 CT1328 bchF bchF bchC bchC bchX bchX hemA hemA hemC hemC hemD hemD hemB hemB bchG bchG CT1763 CT1763 CT1776 CT1776 bchQ bchQ bchY bchY CT1955 CT1955 bchH-1 bchH-1 bchM bchM bchE bchE bchK bchK bchJ bchJ hemE hemE hemL hemL bchZ bchZ bchL bchL bchB bchB bchN bchN CT2238 CT2238 CT2239 CT2239 dsrN dsrN bchP bchP
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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bchUC-20 methyltransferase; Involved in the biosynthesis of the major light-harvesting pigment bacteriochlorophyll c (BChlc), which confers a significant competitive advantage to green sulfur bacteria living at limiting red and near-infrared light intensities. Catalyzes the methylation at the C-20 position of the cyclic tetrapyrrole chlorin of bacteriochlorophyll d (BChld) to produce bacteriochlorophyll c (BChlc) using S-adenosylmethionine (SAM) as a methyl source. (338 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (503 aa)
hemNOxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055; match to protein family HMM PF06969; match to protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (476 aa)
cbiDJprecorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (610 aa)
cbiETPrecorrin-6y c5,15-methyltransferase, decarboxylating; Identified by similarity to EGAD:12801; match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. (400 aa)
cbiLPrecorrin-2 C20-methyltransferase; Identified by similarity to EGAD:18341; match to protein family HMM PF00590; Belongs to the precorrin methyltransferase family. (246 aa)
CT0389Cobalt chelatase CbiK, putative; Identified by similarity to EGAD:16278; match to protein family HMM PF06180. (313 aa)
cobAuroporphyrin-III C-methyltransferase; Identified by similarity to EGAD:12949; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. (267 aa)
CT0418cobN protein, putative; Identified by similarity to EGAD:15304; match to protein family HMM PF02514. (1259 aa)
CT0420Magnesium-chelatase, subunit D/I family; Identified by similarity to EGAD:134942; match to protein family HMM PF00092; match to protein family HMM PF01078; match to protein family HMM TIGR02442. (649 aa)
CT0421Identified by similarity to EGAD:49433; match to protein family HMM PF01078. (347 aa)
CT0422cobN protein, putative; Identified by similarity to EGAD:15304; match to protein family HMM PF02514. (1179 aa)
cbiA-1Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (459 aa)
cbiPCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (500 aa)
cbiBCobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (319 aa)
btuRcob(I)alamin adenosyltransferase; Identified by similarity to EGAD:20443; match to protein family HMM PF02572. (174 aa)
cobPCobalamin biosynthesis protein CobP; Identified by similarity to EGAD:21537; match to protein family HMM PF02283. (172 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (353 aa)
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (267 aa)
CT1063Conserved hypothetical protein; Identified by similarity to EGAD:76752; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368; match to protein family HMM PF07993. (344 aa)
CT1077Hypothetical protein; Identified by Glimmer2; putative. (193 aa)
chlGBacteriochlorophyll synthase, 34 kDa subunit; Identified by similarity to SP:P33326; match to protein family HMM PF01040; match to protein family HMM TIGR01476. (367 aa)
bchH-3Magnesium-protoporphyrin methyltransferase; Identified by similarity to GP:2661856; match to protein family HMM PF02514; match to protein family HMM TIGR02025. (1271 aa)
bchDMagnesium-chelatase, subunit D; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (620 aa)
bchIMagnesium-chelatase, subunit I; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (392 aa)
bchRBchE/P-methylase family protein; Involved in the biosynthesis of the major light-harvesting pigment bacteriochlorophyll c (BChlc), which confers a significant competitive advantage to green sulfur bacteria living at limiting red and near-infrared light intensities. BchR is a methyltransferase that adds a single methyl group to the methyl carbon at the C-12(1) position of 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d to yield 8,12- diethyl-3-vinylbacteriochlorophyllide d; Belongs to the radical SAM superfamily. (456 aa)
CT1328Conserved hypothetical protein; Identified by similarity to EGAD:171115; match to protein family HMM PF00210; Belongs to the Dps family. (164 aa)
bchF2-vinyl bacteriochlorophyllide hydratase; Identified by similarity to EGAD:8942; match to protein family HMM PF07284; match to protein family HMM TIGR02020. (158 aa)
bchC2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; Identified by similarity to EGAD:9474; match to protein family HMM PF00107; match to protein family HMM TIGR01202. (337 aa)
bchXChlorophyllide reductase, BchX subunit; Identified by similarity to EGAD:10210; match to protein family HMM PF00142; match to protein family HMM TIGR02016; Belongs to the NifH/BchL/ChlL family. (384 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (426 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (312 aa)
hemDuroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa)
hemBDelta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. (328 aa)
bchGBacteriochlorophyll synthase, 34 kDa subunit; Identified by similarity to SP:P33326; match to protein family HMM PF01040; match to protein family HMM TIGR01476. (330 aa)
CT1763uroporphyrin-III C-methyltransferase; Identified by similarity to EGAD:6870; match to protein family HMM PF00590. (300 aa)
CT1776Bacteriochlorophyll c3(1) hydratase; Identified by similarity to EGAD:8942; match to protein family HMM PF07284; match to protein family HMM TIGR02020. (190 aa)
bchQBacteriochlorophyll c8 methyltransferase; Involved in the biosynthesis of the major light-harvesting pigment bacteriochlorophyll c (BChlc), which confers a significant competitive advantage to green sulfur bacteria living at limiting red and near-infrared light intensities. BchQ is a methyltransferase that adds two consecutive methyl groups to the ethyl carbon at the C-8(2) position of 8,12-diethyl-3-vinylbacteriochlorophyllide d to yield 12- ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d. (451 aa)
bchYChlorophyllide reductase, BchY subunit; Identified by similarity to EGAD:10229; match to protein family HMM PF00148; match to protein family HMM TIGR02015. (407 aa)
CT1955Magnesium-chelatase, bacteriochlorophyll c-specific subunit; Identified by similarity to GP:2661856; match to protein family HMM PF02514; match to protein family HMM TIGR02025. (1295 aa)
bchH-1Magnesium-protoporphyrin methyltransferase; Identified by similarity to EGAD:6772; match to protein family HMM PF02514; match to protein family HMM TIGR02025. (1278 aa)
bchMMagnesium-protoporphyrin IX monomethyl ester oxidative cyclase, 25 kDa subunit; Identified by similarity to EGAD:8986; match to protein family HMM PF07109; match to protein family HMM TIGR02021. (232 aa)
bchEMagnesium-protoporphyrin IX monomethyl ester oxidative cyclase, 66 kDa subunit; Identified by similarity to EGAD:9307; match to protein family HMM PF02310; match to protein family HMM PF04055; match to protein family HMM TIGR02026. (546 aa)
bchKBacteriochlorophyll c synthase; Identified by similarity to SP:P33326; match to protein family HMM PF01040. (358 aa)
bchJBacteriochlorophyll synthase, 23 kDa subunit; Identified by similarity to GP:3820550; match to protein family HMM TIGR02019. (191 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (351 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase; Identified by similarity to EGAD:19989; match to protein family HMM PF00202; match to protein family HMM TIGR00713; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (431 aa)
bchZChlorophyllide reductase, bchZ subunit; Identified by similarity to EGAD:8283; match to protein family HMM PF00148; match to protein family HMM PF06710; match to protein family HMM TIGR02014. (468 aa)
bchLProtochlorophyllide reductase, iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (276 aa)
bchBProtochlorophyllide reductase, ChlB subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (537 aa)
bchNProtochlorophyllide reductase, ChlN subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (420 aa)
CT2238Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. (461 aa)
CT2239Porphyrin biosynthesis protein, putative; Similar to N-terminal 140 aa of E. coli cysG (siroheme synthase) and adjacent to hemD, which is similar to the remainder of cysG; identified by similarity to EGAD:6104; match to protein family HMM TIGR01470. (157 aa)
dsrNdsrN protein; Identified by similarity to EGAD:103680; match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379. (460 aa)
bchPGeranylgeranyl hydrogenase; Identified by similarity to EGAD:102228; match to protein family HMM PF01360; match to protein family HMM PF07992; match to protein family HMM TIGR02023; match to protein family HMM TIGR02032. (383 aa)
Your Current Organism:
Chlorobaculum tepidum
NCBI taxonomy Id: 194439
Other names: C. tepidum TLS, Chlorobaculum tepidum TLS, Chlorobium tepidum TLS
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