| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bolA | yjaA | c0548 | c4968 | BolA protein; Transcriptional regulator that plays an important role in general stress response. | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | 0.427 |
| bolA | yliH | c0548 | c0921 | BolA protein; Transcriptional regulator that plays an important role in general stress response. | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | 0.548 |
| chuA | yjaA | c4308 | c4968 | Outer membrane heme/hemoglobin receptor; Escherichia coli O157:H7 ortholog: z4911. | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | 0.564 |
| sdiA | ygaG | c2330 | c3244 | Regulatory protein sdiA; Escherichia coli K-12 ortholog: b1916; Escherichia coli O157:H7 ortholog: z3004. | Autoinducer-2 production protein luxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.578 |
| sdiA | yjaA | c2330 | c4968 | Regulatory protein sdiA; Escherichia coli K-12 ortholog: b1916; Escherichia coli O157:H7 ortholog: z3004. | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | 0.563 |
| sdiA | yliH | c2330 | c0921 | Regulatory protein sdiA; Escherichia coli K-12 ortholog: b1916; Escherichia coli O157:H7 ortholog: z3004. | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | 0.520 |
| yceP | yliH | c1327 | c0921 | Hypothetical protein yceP; Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway (By similarity). | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | 0.813 |
| ygaG | sdiA | c3244 | c2330 | Autoinducer-2 production protein luxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Regulatory protein sdiA; Escherichia coli K-12 ortholog: b1916; Escherichia coli O157:H7 ortholog: z3004. | 0.578 |
| ygaG | yjaA | c3244 | c4968 | Autoinducer-2 production protein luxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | 0.493 |
| ygaG | yliH | c3244 | c0921 | Autoinducer-2 production protein luxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | 0.491 |
| yjaA | bolA | c4968 | c0548 | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | BolA protein; Transcriptional regulator that plays an important role in general stress response. | 0.427 |
| yjaA | chuA | c4968 | c4308 | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | Outer membrane heme/hemoglobin receptor; Escherichia coli O157:H7 ortholog: z4911. | 0.564 |
| yjaA | sdiA | c4968 | c2330 | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | Regulatory protein sdiA; Escherichia coli K-12 ortholog: b1916; Escherichia coli O157:H7 ortholog: z3004. | 0.563 |
| yjaA | ygaG | c4968 | c3244 | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | Autoinducer-2 production protein luxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.493 |
| yjaA | yliH | c4968 | c0921 | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | 0.517 |
| yliH | bolA | c0921 | c0548 | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | BolA protein; Transcriptional regulator that plays an important role in general stress response. | 0.548 |
| yliH | sdiA | c0921 | c2330 | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | Regulatory protein sdiA; Escherichia coli K-12 ortholog: b1916; Escherichia coli O157:H7 ortholog: z3004. | 0.520 |
| yliH | yceP | c0921 | c1327 | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | Hypothetical protein yceP; Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway (By similarity). | 0.813 |
| yliH | ygaG | c0921 | c3244 | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | Autoinducer-2 production protein luxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.491 |
| yliH | yjaA | c0921 | c4968 | Hypothetical protein yliH; Escherichia coli K-12 ortholog: b0836; Escherichia coli O157:H7 ortholog: z1062. | Hypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. | 0.517 |