node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HEAR1516 | ackA | HEAR1516 | HEAR1515 | Putative phosphate acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.998 |
HEAR1516 | acsA | HEAR1516 | HEAR0921 | Putative phosphate acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.809 |
HEAR1516 | mmsA | HEAR1516 | HEAR3421 | Putative phosphate acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.564 |
HEAR1516 | prpE | HEAR1516 | HEAR3269 | Putative phosphate acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.635 |
ackA | HEAR1516 | HEAR1515 | HEAR1516 | Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Putative phosphate acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.998 |
ackA | acsA | HEAR1515 | HEAR0921 | Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.930 |
ackA | prpE | HEAR1515 | HEAR3269 | Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.930 |
acsA | HEAR1516 | HEAR0921 | HEAR1516 | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative phosphate acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.809 |
acsA | ackA | HEAR0921 | HEAR1515 | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.930 |
acsA | aptA | HEAR0921 | HEAR2429 | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Omega-amino acid:pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.800 |
acsA | mmsA | HEAR0921 | HEAR3421 | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.946 |
acsA | prpE | HEAR0921 | HEAR3269 | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.912 |
aptA | acsA | HEAR2429 | HEAR0921 | Omega-amino acid:pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.800 |
aptA | mmsA | HEAR2429 | HEAR3421 | Omega-amino acid:pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.953 |
aptA | prpE | HEAR2429 | HEAR3269 | Omega-amino acid:pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.800 |
mmsA | HEAR1516 | HEAR3421 | HEAR1516 | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative phosphate acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.564 |
mmsA | acsA | HEAR3421 | HEAR0921 | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.946 |
mmsA | aptA | HEAR3421 | HEAR2429 | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Omega-amino acid:pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.953 |
mmsA | prpE | HEAR3421 | HEAR3269 | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.946 |
prpE | HEAR1516 | HEAR3269 | HEAR1516 | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative phosphate acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.635 |