STRINGSTRING
gtfB gtfB gtfC gtfC groEL groEL sacB sacB gbpA gbpA gbpB gbpB brpA brpA luxS luxS spaP spaP sod sod dnaK dnaK rgpE rgpE SMU_833 SMU_833 gtfD gtfD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gtfBglucosyltransferase-I; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1476 aa)
gtfCglucosyltransferase-SI; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1455 aa)
groELPutative chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (542 aa)
sacBLevansucrase precursor; Best Blastp Hit: sp|P11701|SACB_STRMU LEVANSUCRASE## PRECURSOR (BETA-D-FRUCTOFURANOSYL TRANSFERASE) (SUCROSE 6-FRUCTOSYL TRANSFERASE) >gi|79999|pir||B28551 levansucrase (EC 2.4.1.10) precursor - Streptococcus mutans (strain GS-5) >gi|153636|gb|AAA88584.1| (M18954) fructosyltransferase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 68 family. (795 aa)
gbpABest Blastp Hit: pir||A37184 glucan-binding protein - Streptococcus mutans >gi|153638|gb|AAA26894.1| (M30945) glucan-binding protein (gbp) [Streptococcus mutans]. (565 aa)
gbpBBest Blastp Hit: gb|AAD00288.1| (U78607) putative secreted protein [Streptococcus mutans]. (431 aa)
brpAPutative transcriptional regulator; Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood. Belongs to the LytR/CpsA/Psr (LCP) family. (406 aa)
luxSPutative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (160 aa)
spaPCell surface antigen SpaP; Surface protein antigen implicated in dental caries; Belongs to the SpaP/Ssp5/SpaA family. (1562 aa)
sodPutative manganese-type superoxide dismutase, Fe/Mn-SOD; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (203 aa)
dnaKHeat shock protein, DnaK (HSP-70); Acts as a chaperone; Belongs to the heat shock protein 70 family. (612 aa)
rgpEBest Blastp Hit: pir||T00090 glycosyltransferase rgpEc - Streptococcus mutans >gi|3399708|dbj|BAA32093.1| (AB010970) glycosyltransferase [Streptococcus mutans]. (465 aa)
SMU_833Putative glycosyltransferase; Best Blastp Hit: sp|Q45539|CSBB_BACSU CSBB PROTEIN >gi|2126920|pir||JC5173 stress response protein csbB - Bacillus subtilis >gi|1387979|gb|AAB38429.1| (L77099) 44% identity over 302 residues with hypothetical protein from Synechocystis sp, accession D64006_CD; expression induced by environmental stress; some similarity to glycosyl transferases; two potential membrane-spanning helices [Bacillus subtil> >gi|2633183|emb|CAB12688.1| (Z99108) stress response protein [Bacillus subtilis] >gi|2804544|dbj|BAA24480.1| (D85082) YfhN [Bacillus subtilis]. (308 aa)
gtfDglucosyltransferase-S; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1462 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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