STRINGSTRING
menC menC fdnI fdnI gspC gspC gspN gspN ccmE ccmE ccmA ccmA ccmH ccmH ubiA ubiA dsbD dsbD nqrF nqrF nqrF-2 nqrF-2 ifcA ifcA dmsE dmsE dmsF dmsF dmsH dmsH mtrB mtrB mtrA mtrA mtrC mtrC omcA omcA mtrF mtrF mtrE mtrE mtrD mtrD menA menA ybaY ybaY hemH hemH fnr fnr SO_3300 SO_3300 hemH2 hemH2 pilU pilU omp35 omp35 SO_4357 SO_4357 SO_4359 SO_4359 SO_4362 SO_4362 azoR azoR moaC moaC menD menD cymA cymA menF menF hemN hemN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
menCO-succinylbenzoate-CoA synthase MenC; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (374 aa)
fdnINitrate-inducible formate dehydrogenase cytochrome b subunit FdnI. (213 aa)
gspCT2aSS secretion system protein GspC. (308 aa)
gspNT2aSS secretion system protein GspN. (253 aa)
ccmEABC-type heme export system chaperone component CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity); Belongs to the CcmE/CycJ family. (161 aa)
ccmAABC-type heme export system ATPase component CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (216 aa)
ccmHCytochrome c synthetase subunit CcmH; Possible subunit of a heme lyase. (159 aa)
ubiA4-hydroxybenzoate octaprenyltransferase UbiA; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (286 aa)
dsbDProtein-disulfide reductase DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (610 aa)
nqrFNa-translocating NADH-quinone reductase subunit F NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (405 aa)
nqrF-2Na-translocating NADH-quinone reductase subunit F NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (418 aa)
ifcAPeriplasmic tetraheme flavocytochrome IfcA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (589 aa)
dmsEPeriplasmic decaheme cytochrome c DmsE. (318 aa)
dmsFExtracellular dimethyl sulfoxide/manganese oxide reductase outer membrane translocase DmsF. (662 aa)
dmsHExtracellular dimethyl sulfoxide/manganese oxide reductase accessory protein DmsH. (155 aa)
mtrBExtracellular iron oxide respiratory system outer membrane component MtrB. (697 aa)
mtrAExtracelllular iron oxide respiratory system periplasmic decaheme cytochrome c component MtrA. (333 aa)
mtrCExtracellular iron oxide respiratory system surface decaheme cytochrome c component MtrC. (671 aa)
omcAExtracelllular iron oxide respiratory system surface decaheme cytochrome c component OmcA. (735 aa)
mtrFExtracellular respiratory system surface decaheme cytochrome c component MtrF. (639 aa)
mtrEExtracellular respiratory sytem outer membrane component MtrE. (712 aa)
mtrDExtracellular respiratory system periplasmic decaheme cytochrome c component MtrD. (321 aa)
menA1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (291 aa)
ybaYPutative chaperone for general secretion pathway YbaY. (134 aa)
hemHFerrochelatase HemH; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (334 aa)
fnrOxygen-responsive transcriptional regulator of anaerobiosis response Fnr; Regulates anaerobic growth on fumarate, nitrite, Fe(3+), TMAO, DMSO, thiosulfate and sulfite, but not on nitrate nor Mn(4+). (250 aa)
SO_3300Flavocytochrome c heme submit. (124 aa)
hemH2Ferrochelatase HemH; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (327 aa)
pilUPilus retraction ATPase PilU. (370 aa)
omp35Outer membrane porin Omp35. (369 aa)
SO_4357Extracellular oxidoreductase FeS binding subunit. (205 aa)
SO_4359Outer membrane protein MtrB family. (656 aa)
SO_4362Extracellular oxidoreductase chaperone protein. (225 aa)
azoRFMN-dependent NADH-azoreductase AzoR; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (198 aa)
moaCMolybdenum cofactor biosynthesis protein C MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (159 aa)
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase MenD; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (573 aa)
cymAMembrane anchored tetraheme cytochrome c CymA. (187 aa)
menFMenaquinone-specific isochorismate synthase MenF; Catalyzes the conversion of chorismate to isochorismate. (452 aa)
hemNCoproporphyrinogen III oxidase oxygen-independent HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (458 aa)
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.