STRINGSTRING
A7J50_5388 A7J50_5388 A7J50_4229 A7J50_4229 queC queC guaA guaA queC-2 queC-2 gluQ gluQ panC panC A7J50_5124 A7J50_5124 trpS trpS mnmA mnmA ttcA ttcA A7J50_3299 A7J50_3299 A7J50_2020 A7J50_2020 A7J50_1860 A7J50_1860 A7J50_1832 A7J50_1832 A7J50_1676 A7J50_1676 tilS tilS metG metG argG argG thiI thiI argS argS hldE hldE nadE nadE A7J50_0754 A7J50_0754 cysD cysD A7J50_0772 A7J50_0772 ileS ileS cysS cysS glnS glnS gltX gltX A7J50_3998 A7J50_3998 coaD coaD cysH cysH A7J50_4440 A7J50_4440 A7J50_4441 A7J50_4441 valS valS leuS leuS nadD nadD tyrS tyrS A7J50_5387 A7J50_5387
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A7J50_5388Pfam:pfam00766 Electron transfer flavoprotein FAD-binding domain. (406 aa)
A7J50_4229Pfam:pfam01507 Phosphoadenosine phosphosulfate reductase family. (480 aa)
queC7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (225 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (525 aa)
queC-2Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (232 aa)
gluQglutamyl-Q tRNA(Asp) ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (295 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa)
A7J50_5124Membrane protein; Pfam:pfam02698 DUF218 domain. (253 aa)
trpSTryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (455 aa)
mnmAtRNA 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (374 aa)
ttcAtRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (274 aa)
A7J50_3299Pfam:pfam04244 Deoxyribodipyrimidine photo-lyase-related protein. (512 aa)
A7J50_2020Pfam:pfam02702 Osmosensitive K+ channel His kinase sensor domain. (883 aa)
A7J50_1860Pfam:pfam00582 Universal stress protein family. (166 aa)
A7J50_1832Histidine kinase; Pfam:pfam02702 Osmosensitive K+ channel His kinase sensor domain. (883 aa)
A7J50_1676Pfam:pfam00582 Universal stress protein family. (150 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (439 aa)
metGMethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (683 aa)
argGPfam:pfam00764 Arginosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
thiItRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (484 aa)
argSPfam:pfam00750 tRNA synthetases class I (R). (578 aa)
hldEBifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (474 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (275 aa)
A7J50_0754Deoxyribodipyrimidine photo-lyase; Pfam:pfam03441 FAD binding domain of DNA photolyase. (481 aa)
cysDSulfate adenylyltransferase subunit 2; Pfam:pfam01507 Phosphoadenosine phosphosulfate reductase family. (305 aa)
A7J50_0772FMN adenylyltransferase; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. (312 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (943 aa)
cysSCysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. (462 aa)
glnSglutamate--tRNA ligase; Pfam:pfam00749 tRNA synthetases class I (E and Q), catalytic domain. (566 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (493 aa)
A7J50_3998Asparagine synthetase; Pfam:pfam13537 Glutamine amidotransferase domain. (590 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (244 aa)
A7J50_4440Electron transfer flavoprotein, alpha subunit; Pfam:pfam00766 Electron transfer flavoprotein FAD-binding domain. (309 aa)
A7J50_4441Pfam:pfam01012 Electron transfer flavoprotein domain. (249 aa)
valSValine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (948 aa)
leuSleucine--tRNA ligase; Pfam:pfam13603 Leucyl-tRNA synthetase, Domain 2; Belongs to the class-I aminoacyl-tRNA synthetase family. (868 aa)
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (214 aa)
tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (399 aa)
A7J50_5387Pfam:pfam01012 Electron transfer flavoprotein domain. (256 aa)
Your Current Organism:
Pseudomonas antarctica
NCBI taxonomy Id: 219572
Other names: CCUG 49625, DSM 15318, LMG 22709, LMG:22709, MTCC 4992, Pseudomonas antarctica Reddy et al. 2004, strain CMS 35
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.