STRINGSTRING
STY0108 STY0108 yaeT yaeT STY0698 STY0698 STY0790 STY0790 STY0791 STY0791 STY0792 STY0792 STY0793 STY0793 STY0794 STY0794 STY0795 STY0795 STY0796 STY0796 STY0959 STY0959 STY1257 STY1257 STY1258 STY1258 STY1259 STY1259 STY1904 STY1904 STY2726 STY2726 STY2765 STY2765 STY2852 STY2852 STY2871 STY2871 STY3496 STY3496 STY3497 STY3497 STY3498 STY3498 STY4817 STY4817 STY4818 STY4818
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STY0108Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Belongs to the LptD family. (784 aa)
yaeTOuter membrane protein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. (803 aa)
STY0698Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (196 aa)
STY0790Conserved hypothetical protein; Orthologue of E. coli ybgC (YBGC_ECOLI); Fasta hit to YBGC_ECOLI (134 aa), 92% identity in 134 aa overlap. (134 aa)
STY0791TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (230 aa)
STY0792tolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (142 aa)
STY0793tolA protein; Orthologue of E. coli tolA (TOLA_ECOLI); Fasta hit to TOLA_ECOLI (421 aa), 68% identity in 421 aa overlap. (376 aa)
STY0794tolB protein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (430 aa)
STY0795Peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (174 aa)
STY0796Putative exported protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (262 aa)
STY0959Outer membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (204 aa)
STY1257ABC transporter integral membrane subunit; Orthologue of E. coli YCFU_ECOLI; Fasta hit to YCFU_ECOLI (399 aa), 94% identity in 399 aa overlap. (436 aa)
STY1258ABC transporter ATP-binding subunit; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (233 aa)
STY1259ABC transporter integral membrane subunit; Orthologue of E. coli YCFW_ECOLI; Fasta hit to YCFW_ECOLI (414 aa), 93% identity in 414 aa overlap. (414 aa)
STY1904Outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. (207 aa)
STY2726Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (344 aa)
STY2765Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (392 aa)
STY2852Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. (245 aa)
STY2871Small protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (112 aa)
STY3496Possible exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa)
STY3497Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (172 aa)
STY3498Probable ABC transport protein, ATP-binding component; Fasta hit to ARTP_ECOLI (242 aa), 30% identity in 212 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 30% identity in 203 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 33% identity in 233 aa overlap; Fasta hit to LIVF_ECOLI (237 aa), 35% identity in 229 aa overlap; Fasta hit to FECE_ECOLI (255 aa), 31% identity in 237 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 32% identity in 238 aa overlap; Fasta hit to LIVG_ECOLI (255 aa), 32% identity in 249 aa overlap; Fasta hit to FTSE_ECOLI (222 aa), 30% identity in 216 aa overlap; Fasta hit [...] (241 aa)
STY4817Probable inner membrane protein. Similar to Escherichia coli hypothetical protein YjgP SW:YJGP_ECOLI (P39340) (366 aa) fasta scores: E(): 0, 95.3% id in 359 aa and to Haemophilus influenzae hypothetical protein HI1704 SW:YJGP_HAEIN (P45333) (372 aa) fasta scores: E(): 0, 47.8% id in 358 aa. (366 aa)
STY4818Probable inner membrane protein. Similar to Escherichia coli hypothetical 39.8 kDa protein in pepA-gntV intergenic region YjgQ SW:YJGQ_ECOLI (P39341) (361 aa) fasta scores: E(): 0, 96.9% id in 360 aa, and to Haemophilus influenzae hypothetical protein HI1703 HI1703 SW:YJGQ_HAEIN (P45332) (358 aa) fasta scores: E(): 0, 53.8% id in 353 aa. (360 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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