STRINGSTRING
valS valS pheT pheT proS proS gltX gltX rps2p rps2p rps9p rps9p rpl13 rpl13 rpl18e rpl18e rps11 rps11 rps4p rps4p rps13 rps13 Abm4_1248 Abm4_1248 rpl34e rpl34e rpl15 rpl15 rpl30 rpl30 rps5p rps5p rpl18 rpl18 rpl19e rpl19e Abm4_1259 Abm4_1259 rpl6p rpl6p rps8p rps8p rps14 rps14 rpl5p rpl5p rps4e rps4e rpl24 rpl24 rpl14 rpl14 rps17 rps17 Abm4_1269 Abm4_1269 rpl29 rpl29 rps3p rps3p rpl22 rpl22 rps19p rps19p rpl2p rpl2p rpl23 rpl23 rpl4p rpl4p rpl3p rpl3p Abm4_1287 Abm4_1287 Abm4_1301 Abm4_1301 dphB dphB moaB moaB glyS glyS Abm4_1344 Abm4_1344 Abm4_1355 Abm4_1355 Abm4_1381 Abm4_1381 eif2b eif2b tyrS tyrS ubiB ubiB thiS thiS Abm4_1456 Abm4_1456 Abm4_1457 Abm4_1457 ef1b ef1b Abm4_1466 Abm4_1466 moeA2 moeA2 eif1a eif1a Abm4_1503 Abm4_1503 psmB psmB cobB cobB gatB gatB hypF hypF map map frhD frhD Abm4_1639 Abm4_1639 eif2a eif2a rps27e rps27e rpl44e rpl44e Abm4_1650 Abm4_1650 Abm4_1653 Abm4_1653 rpl21e rpl21e Abm4_1672 Abm4_1672 Abm4_1682 Abm4_1682 moeA1 moeA1 ileS ileS Abm4_1696 Abm4_1696 Abm4_1697 Abm4_1697 Abm4_0186 Abm4_0186 Abm4_0192 Abm4_0192 rps19e rps19e rpl39e rpl39e rpl31e rpl31e eif6 eif6 rplX rplX rps3ae rps3ae hypC hypC spt5 spt5 rpl11 rpl11 gatA gatA thrS thrS Abm4_0051 Abm4_0051 argS argS Abm4_0080 Abm4_0080 rps15 rps15 leuS leuS cbiE cbiE rfbD rfbD moaA moaA mobB mobB lysS lysS moeB moeB rpl1 rpl1 rpl10 rpl10 rpl12 rpl12 alaS alaS gspE gspE Abm4_0286 Abm4_0286 hypD hypD Abm4_0292 Abm4_0292 Abm4_0319 Abm4_0319 rpl30e rpl30e rps12 rps12 rps7 rps7 fusA fusA tuf tuf rps10 rps10 rimI rimI Abm4_0368 Abm4_0368 Abm4_0399 Abm4_0399 Abm4_0400 Abm4_0400 Abm4_0404 Abm4_0404 Abm4_0408 Abm4_0408 prf1 prf1 hemC hemC eif5a eif5a Abm4_0489 Abm4_0489 Abm4_0493 Abm4_0493 Abm4_0506 Abm4_0506 Abm4_0507 Abm4_0507 Abm4_0515 Abm4_0515 moaC moaC sppA sppA rps17e rps17e Abm4_0585 Abm4_0585 Abm4_0598 Abm4_0598 hypA hypA hypB hypB Abm4_0629 Abm4_0629 metG metG aspS aspS Abm4_0702 Abm4_0702 trpS trpS rpl7ae rpl7ae rps28e rps28e rpl24e rpl24e infB infB rps6e rps6e eif2g eif2g rps24e rps24e rps27ae rps27ae Abm4_0745 Abm4_0745 dhys dhys Abm4_0756 Abm4_0756 mobA mobA cbiT cbiT moaE moaE hisS hisS htpX htpX Abm4_0797 Abm4_0797 rpl37e rpl37e Abm4_0818 Abm4_0818 Abm4_0821 Abm4_0821 pepA pepA rpl40e rpl40e Abm4_0898 Abm4_0898 rpl37ae rpl37ae psmA psmA Abm4_0926 Abm4_0926 gatD gatD gatE gatE pan pan Abm4_0987 Abm4_0987 Abm4_1023 Abm4_1023 Abm4_1036 Abm4_1036 Abm4_1037 Abm4_1037 serS serS Abm4_1131 Abm4_1131 hypE hypE rps8e rps8e pheS pheS fdhD fdhD cysS cysS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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valSvalyl-tRNA synthetase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (909 aa)
pheTphenylalanyl-tRNA synthetase subunit beta PheT. (552 aa)
proSprolyl-tRNA synthetase ProS; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (469 aa)
gltXglutamyl-tRNA synthetase GltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (557 aa)
rps2pRibosomal protein S2P Rps2p; Belongs to the universal ribosomal protein uS2 family. (200 aa)
rps9pRibosomal protein S9P Rps9p; Belongs to the universal ribosomal protein uS9 family. (132 aa)
rpl13Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa)
rpl18eRibosomal protein L18e Rpl18e; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa)
rps11Ribosomal protein S11P Rps11p; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa)
rps4pRibosomal protein S4P Rps4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa)
rps13Ribosomal protein S13P Rps13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (153 aa)
Abm4_1248Ribosomal protein L14e Rpl14e. (73 aa)
rpl34eRibosomal protein L34e Rpl34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa)
rpl15Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa)
rpl30Ribosomal protein L30P Rpl30p. (152 aa)
rps5pRibosomal protein S5P Rps5p; With S4 and S12 plays an important role in translational accuracy. (214 aa)
rpl18Ribosomal protein L18P Rpl18p; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa)
rpl19eRibosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa)
Abm4_1259Ribosomal protein L32e Rpl32e. (108 aa)
rpl6pRibosomal protein L6P Rpl6p; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
rps8pRibosomal protein S8P Rps8p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rps14Ribosomal protein S14P Rps14p; Binds 16S rRNA, required for the assembly of 30S particles. (47 aa)
rpl5pRibosomal protein L5P Rpl5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (171 aa)
rps4eRibosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family. (241 aa)
rpl24Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa)
rpl14Ribosomal protein L14P Rpl14p; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rps17Ribosomal protein S17P Rps17p; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (105 aa)
Abm4_1269Translation initiation factor aSUI1; Belongs to the SUI1 family. (115 aa)
rpl29Ribosomal protein L29P Rpl29p; Belongs to the universal ribosomal protein uL29 family. (68 aa)
rps3pRibosomal protein S3P Rps3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (254 aa)
rpl22Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (154 aa)
rps19pRibosomal protein S19P Rps19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa)
rpl2pRibosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa)
rpl23Ribosomal protein L23P Rpl23p; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa)
rpl4pRibosomal protein L4p Rpl4p; Forms part of the polypeptide exit tunnel. (254 aa)
rpl3pRibosomal protein L3P Rpl3p; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (336 aa)
Abm4_1287RNA-binding protein. (664 aa)
Abm4_1301CBS domain-containing protein. (134 aa)
dphBDiphthine synthase DphB; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. (264 aa)
moaBMolybdenum cofactor biosynthesis protein B MoaB. (174 aa)
glySglycyl-tRNA synthetase GlyS. (568 aa)
Abm4_1344CAAX amino terminal protease family protein. (233 aa)
Abm4_1355Macro domain-containing protein. (262 aa)
Abm4_1381Hypothetical protein. (220 aa)
eif2bTranslation initiation factor aIF-2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (137 aa)
tyrStyrosyl-tRNA synthetase TyrS; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (320 aa)
ubiB2-polyprenylphenol 6-hydroxylase UbiB. (546 aa)
thiSThiamine biosynthesis protein ThiS. (66 aa)
Abm4_1456ATPase RIL. (591 aa)
Abm4_1457peptidyl-tRNA hydrolase. (112 aa)
ef1bTranslation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa)
Abm4_1466CAAX amino terminal protease family protein. (309 aa)
moeA2Molybdopterin biosynthesis protein MoeA2. (406 aa)
eif1aTranslation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (104 aa)
Abm4_1503Ribosomal protein L10e Rpl10e. (160 aa)
psmBProteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (208 aa)
cobBNAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (245 aa)
gatBAsp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit B GatB; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (450 aa)
hypFHydrogenase maturation factor HypF. (780 aa)
mapMethionine aminopeptidase Map; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (311 aa)
frhDCoenzyme F420 hydrogenase delta subunit FrhD. (159 aa)
Abm4_1639Hypothetical protein. (399 aa)
eif2aTranslation initiation factor aIF-2 alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (265 aa)
rps27eRibosomal protein S27e Rps27e. (59 aa)
rpl44eRibosomal protein L44e Rpl44e; Binds to the 23S rRNA. (92 aa)
Abm4_1650NUDIX domain-containing protein. (137 aa)
Abm4_1653Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (336 aa)
rpl21eRibosomal protein L21e Rpl21e; Belongs to the eukaryotic ribosomal protein eL21 family. (96 aa)
Abm4_1672Peptidyl-prolyl cis-trans isomerase. (142 aa)
Abm4_1682Peptidase M50 family. (386 aa)
moeA1Molybdopterin biosynthesis protein MoeA1. (408 aa)
ileSisoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1107 aa)
Abm4_1696Glycosyl transferase GT2 family. (288 aa)
Abm4_1697Glycosyl transferase GT2 family. (322 aa)
Abm4_0186Oligosaccharyl transferase. (906 aa)
Abm4_0192GTP-binding protein. (369 aa)
rps19eRibosomal protein S19e Rps19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa)
rpl39eRibosomal protein L39e Rpl39e; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa)
rpl31eRibosomal protein L31e Rpl31e; Belongs to the ribosomal protein L31e family. (88 aa)
eif6Translation initiation factor aIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa)
rplXRibosomal protein LX RplX. (74 aa)
rps3aeRibosomal protein S3Ae Rps3ae; Belongs to the eukaryotic ribosomal protein eS1 family. (191 aa)
hypCHydrogenase assembly chaperone HypC. (89 aa)
spt5Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (160 aa)
rpl11Ribosomal protein L11P Rpl11p; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (161 aa)
gatAAsp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit A GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (459 aa)
thrSthreonyl-tRNA synthetase ThrS; Belongs to the class-II aminoacyl-tRNA synthetase family. (611 aa)
Abm4_0051Signal peptidase I. (140 aa)
argSarginyl-tRNA synthetase ArgS; Belongs to the class-I aminoacyl-tRNA synthetase family. (574 aa)
Abm4_0080Universal archaeal protein Kae1; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (549 aa)
rps15Ribosomal protein S15P Rps15p. (132 aa)
leuSleucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. (955 aa)
cbiEPrecorrin-6y C5,15-methyltransferase (decarboxylating) CbiE. (213 aa)
rfbDdTDP-4-dehydrorhamnose reductase RfbD. (277 aa)
moaAMolybdopterin cofactor biosynthesis protein A MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (310 aa)
mobBMolybdopterin-guanine dinucleotide biosynthesis protein B MobB. (234 aa)
lysSlysyl-tRNA synthetase LysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (528 aa)
moeBMolybdopterin biosynthesis protein MoeB. (251 aa)
rpl1Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa)
rpl10Acidic ribosomal protein P0 RplPO; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (336 aa)
rpl12Ribosomal protein L12P Rpl12p; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (100 aa)
alaSalanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (906 aa)
gspEType II secretion system protein E GspE. (608 aa)
Abm4_0286Peptidase U62 family. (435 aa)
hypDHydrogenase expression/formation protein HypD. (348 aa)
Abm4_0292Sialyltransferase. (482 aa)
Abm4_0319Hypothetical protein; Belongs to the LarC family. (406 aa)
rpl30eRibosomal protein L30e Rpl30e; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa)
rps12Ribosomal protein S12P Rps12p; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (141 aa)
rps7Ribosomal protein S7P Rps7p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (187 aa)
fusATranslation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (730 aa)
tufTranslation elongation factor aEF-1 alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa)
rps10Ribosomal protein S10P Rps10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rimIRibosomal-protein-alanine acetyltransferase RimI. (149 aa)
Abm4_0368Adhesin-like protein with PMBR domain. (379 aa)
Abm4_0399Peptidase M50 family. (209 aa)
Abm4_0400Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. (352 aa)
Abm4_0404tRNA binding domain-containing protein. (241 aa)
Abm4_0408Hypothetical protein. (272 aa)
prf1Peptide chain release factor aRF1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (411 aa)
hemCPorphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (291 aa)
eif5aTranslation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (135 aa)
Abm4_0489Peptidase U62 family. (455 aa)
Abm4_0493Hypothetical protein. (235 aa)
Abm4_0506HTH domain-containing protein. (109 aa)
Abm4_0507Hypothetical protein. (238 aa)
Abm4_0515Hypothetical protein. (211 aa)
moaCMolybdenum cofactor biosynthesis protein C MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (157 aa)
sppASignal peptide peptidase SppA. (288 aa)
rps17eRibosomal protein S17e Rps17e; Belongs to the eukaryotic ribosomal protein eS17 family. (64 aa)
Abm4_0585Hypothetical protein. (221 aa)
Abm4_0598ATP-dependent protease S16 family; Belongs to the peptidase S16 family. (701 aa)
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (124 aa)
hypBHydrogenase accessory protein HypB. (220 aa)
Abm4_0629Hypothetical protein. (278 aa)
metGmethionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (671 aa)
aspSaspartyl-tRNA synthetase AspS; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa)
Abm4_0702Adhesin-like protein with transglutaminase and PMBR domains. (1324 aa)
trpStryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). (363 aa)
rpl7aeRibosomal protein L7Ae Rpl7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa)
rps28eRibosomal protein S28e Rps28e; Belongs to the eukaryotic ribosomal protein eS28 family. (68 aa)
rpl24eRibosomal protein L24e Rpl24e; Binds to the 23S rRNA. (53 aa)
infBTranslation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (595 aa)
rps6eRibosomal protein S6e Rps6e; Belongs to the eukaryotic ribosomal protein eS6 family. (126 aa)
eif2gTranslation initiation factor aIF-2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (410 aa)
rps24eRibosomal protein S24e Rps24e; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa)
rps27aeRibosomal protein S27ae Rps27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (51 aa)
Abm4_0745Hypothetical protein. (586 aa)
dhysDeoxyhypusine synthase Dhys. (344 aa)
Abm4_0756Glycosyl transferase GT2 family. (230 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (208 aa)
cbiTprecorrin-6Y C5,15- methyltransferase (decarboxylating) CbiT; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. (188 aa)
moaEMolybdenum cofactor biosynthesis protein E MoaE. (150 aa)
hisShistidyl-tRNA synthetase HisS; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa)
htpXPeptidase M48 family; Belongs to the peptidase M48B family. (321 aa)
Abm4_0797RNA-binding protein. (159 aa)
rpl37eRibosomal protein L37e Rpl37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (61 aa)
Abm4_0818ATP-binding protein. (227 aa)
Abm4_0821Type IV leader peptidase family protein. (279 aa)
pepAGlutamyl aminopeptidase PepA. (356 aa)
rpl40eRibosomal protein L40e Rpl40e; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa)
Abm4_0898Signal peptidase I. (216 aa)
rpl37aeRibosomal protein L37Ae Rpl37ae; Binds to the 23S rRNA. (87 aa)
psmAProteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (263 aa)
Abm4_0926Ribosomal protein L15e Rpl15e. (184 aa)
gatDglutamyl-tRNA(Gln) amidotransferase subunit D GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (435 aa)
gatEglutamyl-tRNA(Gln) amidotransferase subunit E GatE; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (625 aa)
panProteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (414 aa)
Abm4_0987RNA methylase. (269 aa)
Abm4_1023Hypothetical protein. (401 aa)
Abm4_1036Hypothetical protein. (242 aa)
Abm4_1037HTH domain-containing protein. (106 aa)
serSseryl-tRNA synthetase SerS. (425 aa)
Abm4_1131LemA family protein. (184 aa)
hypEHydrogenase expression/formation protein HypE. (336 aa)
rps8eRibosomal protein S8e Rps8e. (125 aa)
pheSphenylalanyl-tRNA synthetase alpha subunit PheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (520 aa)
fdhDFormate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (276 aa)
cysScysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (487 aa)
Your Current Organism:
Methanobrevibacter sp. AbM4
NCBI taxonomy Id: 224719
Other names: M. sp. AbM4
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