STRINGSTRING
FG06647.1 FG06647.1 FG10180.1 FG10180.1 FG09735.1 FG09735.1 FG06317.1 FG06317.1 FG05194.1 FG05194.1 APS2 APS2 AKR1 AKR1 MON1 MON1 I1SAM5_GIBZE I1SAM5_GIBZE ATG9 ATG9 FG06883.1 FG06883.1 VPS30 VPS30 FG10832.1 FG10832.1 ATG8 ATG8 FG10717.1 FG10717.1 FG10619.1 FG10619.1 FG10272.1 FG10272.1 FG10251.1 FG10251.1 FG10234.1 FG10234.1 FG10092.1 FG10092.1 FG09846.1 FG09846.1 FG09734.1 FG09734.1 FG09721.1 FG09721.1 FG09712.1 FG09712.1 FG09480.1 FG09480.1 FG09361.1 FG09361.1 I1RY40_GIBZE I1RY40_GIBZE ATG24 ATG24 FG08840.1 FG08840.1 FG08630.1 FG08630.1 FG08545.1 FG08545.1 FG08492.1 FG08492.1 FG07939.1 FG07939.1 FG07432.1 FG07432.1 I1RT30_GIBZE I1RT30_GIBZE FG07125.1 FG07125.1 FG06945.1 FG06945.1 A0A098D8G7 A0A098D8G7 FG10034.1 FG10034.1 A0A098DIG7 A0A098DIG7 A0A098DKW7 A0A098DKW7 FG07126.1 FG07126.1 ATG20 ATG20 ATG28 ATG28 A0A098DW43 A0A098DW43 FG06607.1 FG06607.1 FG05182.1 FG05182.1 FG00290.1 FG00290.1 A0A0E0S1S6 A0A0E0S1S6 FG06550.1 FG06550.1 FG09407.1 FG09407.1 FG08982.1 FG08982.1 FG05380.1 FG05380.1 FG10799.1 FG10799.1 FG10964.1 FG10964.1 A0A1C3YHW1 A0A1C3YHW1 A0A1C3YHW7 A0A1C3YHW7 A0A1C3YI02 A0A1C3YI02 A0A1C3YIF4 A0A1C3YIF4 A0A1C3YIF8 A0A1C3YIF8 A0A1C3YIN0 A0A1C3YIN0 PSD2 PSD2 A0A1C3YJY1 A0A1C3YJY1 A0A1C3YK51 A0A1C3YK51 A0A1C3YKB8 A0A1C3YKB8 A0A1C3YLM3 A0A1C3YLM3 A0A1C3YM48 A0A1C3YM48 FG00291.1 FG00291.1 FG00505.1 FG00505.1 FG00870.1 FG00870.1 FG01239.1 FG01239.1 FG01240.1 FG01240.1 FG01276.1 FG01276.1 ATG27 ATG27 FG01852.1 FG01852.1 I1RE15_GIBZE I1RE15_GIBZE FG01890.1 FG01890.1 FG01893.1 FG01893.1 FG01917.1 FG01917.1 FG01964.1 FG01964.1 FG02090.1 FG02090.1 ATG15 ATG15 I1RFV7_GIBZE I1RFV7_GIBZE FG02699.1 FG02699.1 FG02780.1 FG02780.1 I1RJT0_GIBZE I1RJT0_GIBZE FG04120.1 FG04120.1 FG04145.1 FG04145.1 FG04221.1 FG04221.1 FG04259.1 FG04259.1 ATG18 ATG18 FG05226.1 FG05226.1 FG05263.1 FG05263.1 I1RN70_GIBZE I1RN70_GIBZE FG05625.1 FG05625.1 FG05649.1 FG05649.1 FG05844.1 FG05844.1 FG06265.1 FG06265.1 FG06384.1 FG06384.1 FG06646.1 FG06646.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FG06647.1Uncharacterized protein. (706 aa)
FG10180.1Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (294 aa)
FG09735.1AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (713 aa)
FG06317.1AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (747 aa)
FG05194.1Uncharacterized protein. (128 aa)
APS2AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). (143 aa)
AKR1Palmitoyltransferase AKR1; Palmitoyltransferase specific for casein kinase 1. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. (725 aa)
MON1Vacuolar fusion protein MON1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND family. (601 aa)
I1SAM5_GIBZEt-SNARE coiled-coil homology domain-containing protein. (227 aa)
ATG9Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation (By similarity). Plays a key role in the organization of the preautophagosomal structure/phagophore (PAS) assembly site, the nucleating site for formation of the sequestering vesicle (By similarity). Required for mitophagy (By similarity). Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome (By similarity). Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survi [...] (888 aa)
FG06883.1Uncharacterized protein. (628 aa)
VPS30Vacuolar protein sorting-associated protein 30; Required for cytoplasm to vacuole transport (Cvt), autophagy, nucleophagy, and mitophagy, as a part of the autophagy-specific VPS34 PI3-kinase complex I (By similarity). This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure (By similarity). Also involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence [...] (487 aa)
FG10832.1Uncharacterized protein. (228 aa)
ATG8Autophagy-related protein 8; Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation (By similarity). With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similar [...] (118 aa)
FG10717.1Uncharacterized protein. (1075 aa)
FG10619.1Uncharacterized protein. (720 aa)
FG10272.1E3 ubiquitin-protein ligase. (810 aa)
FG10251.1WD_REPEATS_REGION domain-containing protein. (317 aa)
FG10234.1Uncharacterized protein. (779 aa)
FG10092.1Uncharacterized protein. (223 aa)
FG09846.1Uncharacterized protein. (897 aa)
FG09734.1Rad60-SLD_2 domain-containing protein. (260 aa)
FG09721.1Uncharacterized protein. (397 aa)
FG09712.1Arf-GAP domain-containing protein. (479 aa)
FG09480.1Uncharacterized protein. (237 aa)
FG09361.1Uncharacterized protein. (503 aa)
I1RY40_GIBZEWD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (305 aa)
ATG24Sorting nexin-4; Sorting nexin involved in the separation or division of vacuoles throughout the entire life cycle of the cells (By similarity). Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence. Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant. (460 aa)
FG08840.1Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (916 aa)
FG08630.1Uncharacterized protein. (140 aa)
FG08545.1Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (717 aa)
FG08492.1Uncharacterized protein. (642 aa)
FG07939.1Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1220 aa)
FG07432.1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (940 aa)
I1RT30_GIBZEUncharacterized protein. (171 aa)
FG07125.1Uncharacterized protein. (293 aa)
FG06945.1Uncharacterized protein. (1470 aa)
A0A098D8G7Protein transport protein BOS1; SNARE required for protein transport between the ER and the Golgi complex. (235 aa)
FG10034.1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (181 aa)
A0A098DIG7Uncharacterized protein. (249 aa)
A0A098DKW7Uncharacterized protein. (749 aa)
FG07126.1Uncharacterized protein. (390 aa)
ATG20Autophagy-related protein 20; Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy (By similarity). Also involved in endoplasmic reticulum- specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity). Functions in protein retrieval from the endocytic pathway. Required for proper sorting of the v-SNARE protein SNC1 (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence. Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), [...] (617 aa)
ATG28Autophagy-related protein 28; Required for the autophagic degradation of peroxisomes called pexophagy, but not essential for general autophagy (By similarity). Involved in resistance to elevated pH (By similarity). (646 aa)
A0A098DW43PX domain-containing protein. (225 aa)
FG06607.1Uncharacterized protein. (316 aa)
FG05182.1Uncharacterized protein. (1250 aa)
FG00290.1Uncharacterized protein. (2496 aa)
A0A0E0S1S6Uncharacterized protein. (206 aa)
FG06550.1Uncharacterized protein. (668 aa)
FG09407.1ARID domain-containing protein. (742 aa)
FG08982.1MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (448 aa)
FG05380.1Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (821 aa)
FG10799.1Uncharacterized protein. (1036 aa)
FG10964.1Uncharacterized protein; Belongs to the AAA ATPase family. (432 aa)
A0A1C3YHW1Uncharacterized protein. (220 aa)
A0A1C3YHW7AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (987 aa)
A0A1C3YI02ENTH domain-containing protein. (542 aa)
A0A1C3YIF4Uncharacterized protein. (1098 aa)
A0A1C3YIF8Myosin motor domain-containing protein. (1781 aa)
A0A1C3YIN0MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (437 aa)
PSD2Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1130 aa)
A0A1C3YJY1Clat_adaptor_s domain-containing protein. (262 aa)
A0A1C3YK51Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1683 aa)
A0A1C3YKB8Uncharacterized protein. (201 aa)
A0A1C3YLM3Uncharacterized protein. (381 aa)
A0A1C3YM48Uncharacterized protein. (217 aa)
FG00291.1Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (238 aa)
FG00505.1Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (197 aa)
FG00870.1Vps53_N domain-containing protein. (827 aa)
FG01239.1Uncharacterized protein. (165 aa)
FG01240.1Lipase_3 domain-containing protein. (408 aa)
FG01276.1Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (112 aa)
ATG27Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling (By similarity). Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation (By similarity). Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence. Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant. Belongs [...] (348 aa)
FG01852.1B30.2/SPRY domain-containing protein. (510 aa)
I1RE15_GIBZEClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (239 aa)
FG01890.1t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (344 aa)
FG01893.1AP-1 complex subunit gamma. (825 aa)
FG01917.1Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (771 aa)
FG01964.1Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1864 aa)
FG02090.1IPPc domain-containing protein. (971 aa)
ATG15Putative lipase ATG15; Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies (By similarity). Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles (By similarity). The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence. Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant. (636 aa)
I1RFV7_GIBZEUncharacterized protein. (390 aa)
FG02699.1Uncharacterized protein. (390 aa)
FG02780.1Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (957 aa)
I1RJT0_GIBZEUncharacterized protein. (228 aa)
FG04120.1Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (260 aa)
FG04145.1Uncharacterized protein. (110 aa)
FG04221.1Uncharacterized protein. (683 aa)
FG04259.1Uncharacterized protein. (456 aa)
ATG18Autophagy-related protein 18; Component of the PI(3,5)P2 regulatory complex that regulates both the synthesis and turnover of phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2) (By similarity). Plays an important role in osmotically-induced vacuole fragmentation (By similarity). Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy (By similarity). Involved in correct ATG9 trafficking to the pre-autophagosomal structure (By similarity). With ATG2, protects ATG8 from ATG4-mediated cleavage (By similarity). Autophagy is requir [...] (459 aa)
FG05226.1Uncharacterized protein; Belongs to the synaptobrevin family. (215 aa)
FG05263.1GLUE N-terminal domain-containing protein. (644 aa)
I1RN70_GIBZECoatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (527 aa)
FG05625.1Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
FG05649.1DUF1681 domain-containing protein. (254 aa)
FG05844.1Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (846 aa)
FG06265.1WD_REPEATS_REGION domain-containing protein. (1294 aa)
FG06384.1Uncharacterized protein. (944 aa)
FG06646.1Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (189 aa)
Your Current Organism:
Fusarium graminearum
NCBI taxonomy Id: 229533
Other names: F. graminearum PH-1, Fusarium graminearum PH-1, Gibberella zeae PH-1
Server load: medium (48%) [HD]