(69 nodes) Endocytosis network (Fusarium graminearum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A098DLB3	SEC7 domain-containing protein. (1591 aa)
	FG05501.1	Uncharacterized protein. (323 aa)
	A0A098DXB1	Phospholipase. (1220 aa)
	FG05182.1	Uncharacterized protein. (1250 aa)
	A0A0E0S1S6	Uncharacterized protein. (206 aa)
	FG10792.1	PIPK domain-containing protein. (966 aa)
	FG05088.1	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (935 aa)
	A0A1C3YHW1	Uncharacterized protein. (220 aa)
	A0A1C3YHW7	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (987 aa)
	A0A1C3YI02	ENTH domain-containing protein. (542 aa)
	A0A1C3YID2	Uncharacterized protein. (313 aa)
	A0A1C3YIN0	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (437 aa)
	A0A1C3YIX3	Phospholipase. (1825 aa)
	A0A1C3YJ07	Phospholipase. (838 aa)
	A0A1C3YK51	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1683 aa)
	A0A1C3YKX2	Uncharacterized protein. (1113 aa)
	A0A1C3YM48	Uncharacterized protein. (217 aa)
	A0A1C3YN54	Uncharacterized protein. (212 aa)
	FG00291.1	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (238 aa)
	FG00610.1	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	FG00822.1	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (203 aa)
	FG00838.1	Uncharacterized protein; Belongs to the heat shock protein 70 family. (653 aa)
	FG01014.1	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (183 aa)
	FG01155.1	Uncharacterized protein. (318 aa)
	FG01552.1	Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family. (202 aa)
	I1RDK2_GIBZE	BRO1 domain-containing protein. (852 aa)
	FG02011.1	PX domain-containing protein. (558 aa)
	FG02595.1	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (577 aa)
	FG02756.1	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (902 aa)
	FG03595.1	Uncharacterized protein. (245 aa)
	I1RJT0_GIBZE	Uncharacterized protein. (228 aa)
	FG04120.1	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (260 aa)
	FG04168.1	SEC7 domain-containing protein. (1832 aa)
	FG04221.1	Uncharacterized protein. (683 aa)
	FG04259.1	Uncharacterized protein. (456 aa)
	FG04483.1	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	FG05094.1	Uncharacterized protein. (294 aa)
	FG05141.1	Uncharacterized protein. (205 aa)
	FG05263.1	GLUE N-terminal domain-containing protein. (644 aa)
	FG05447.1	Uncharacterized protein. (195 aa)
	FG05645.1	Senescence domain-containing protein. (490 aa)
	FG06209.1	Uncharacterized protein. (203 aa)
	FG07029.1	Uncharacterized protein. (652 aa)
	I1RSD7_GIBZE	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (319 aa)
	FG07573.1	Uncharacterized protein. (183 aa)
	FG08485.1	ENTH domain-containing protein. (578 aa)
	FG08492.1	Uncharacterized protein. (642 aa)
	FG08545.1	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (717 aa)
	FG08656.1	Uncharacterized protein. (611 aa)
	FG08732.1	Uncharacterized protein. (729 aa)
	FG08919.1	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	ATG24	Sorting nexin-4; Sorting nexin involved in the separation or division of vacuoles throughout the entire life cycle of the cells (By similarity). Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence. Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant. (460 aa)
	FG09361.1	Uncharacterized protein. (503 aa)
	FG09499.1	Arf-GAP domain-containing protein. (557 aa)
	FG09712.1	Arf-GAP domain-containing protein. (479 aa)
	FG10048.1	Uncharacterized protein. (434 aa)
	FG10092.1	Uncharacterized protein. (223 aa)
	FG10272.1	E3 ubiquitin-protein ligase. (810 aa)
	FG10503.1	Uncharacterized protein. (212 aa)
	FG10832.1	Uncharacterized protein. (228 aa)
	FG10961.1	MPN domain-containing protein. (541 aa)
	I1S549_GIBZE	Uncharacterized protein. (529 aa)
	I1S559_GIBZE	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (192 aa)
	I1S9S4_GIBZE	Arf-GAP domain-containing protein. (364 aa)
	CAP1	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (273 aa)
	APS2	AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). (143 aa)
	CAP2	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (282 aa)
	FG04400.1	Uncharacterized protein. (195 aa)
	FG09735.1	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (713 aa)

Your Current Organism:

Fusarium graminearum

NCBI taxonomy Id: 229533
Other names: F. graminearum PH-1, Fusarium graminearum PH-1, Gibberella zeae PH-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A098DLB3	A0A1C3YN54	A0A098DLB3	A0A1C3YN54	SEC7 domain-containing protein.	Uncharacterized protein.	0.485
A0A098DLB3	CAP1	A0A098DLB3	Q4I2D7	SEC7 domain-containing protein.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).	0.510
A0A098DLB3	FG01014.1	A0A098DLB3	I1RBS4	SEC7 domain-containing protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.878
A0A098DLB3	FG04168.1	A0A098DLB3	I1RJY4	SEC7 domain-containing protein.	SEC7 domain-containing protein.	0.956
A0A098DLB3	FG04483.1	A0A098DLB3	I1RKR7	SEC7 domain-containing protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.724
A0A098DLB3	FG05088.1	A0A098DLB3	A0A0E0SNZ9	SEC7 domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.531
A0A098DLB3	FG07573.1	A0A098DLB3	I1RTQ9	SEC7 domain-containing protein.	Uncharacterized protein.	0.485
A0A098DLB3	FG09499.1	A0A098DLB3	I1RYP1	SEC7 domain-containing protein.	Arf-GAP domain-containing protein.	0.404
A0A098DLB3	FG09712.1	A0A098DLB3	I1RZ84	SEC7 domain-containing protein.	Arf-GAP domain-containing protein.	0.847
A0A098DLB3	I1S9S4_GIBZE	A0A098DLB3	I1S9S4	SEC7 domain-containing protein.	Arf-GAP domain-containing protein.	0.890
A0A098DXB1	A0A1C3YIX3	A0A098DXB1	A0A1C3YIX3	Phospholipase.	Phospholipase.	0.913
A0A098DXB1	A0A1C3YJ07	A0A098DXB1	A0A1C3YJ07	Phospholipase.	Phospholipase.	0.908
A0A0E0S1S6	A0A1C3YM48	A0A0E0S1S6	A0A1C3YM48	Uncharacterized protein.	Uncharacterized protein.	0.648
A0A0E0S1S6	FG00291.1	A0A0E0S1S6	I1R9X6	Uncharacterized protein.	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.664
A0A0E0S1S6	FG04120.1	A0A0E0S1S6	I1RJT8	Uncharacterized protein.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.627
A0A0E0S1S6	FG04259.1	A0A0E0S1S6	I1RK67	Uncharacterized protein.	Uncharacterized protein.	0.664
A0A0E0S1S6	FG05094.1	A0A0E0S1S6	I1RMA7	Uncharacterized protein.	Uncharacterized protein.	0.994
A0A0E0S1S6	FG05263.1	A0A0E0S1S6	I1RMR7	Uncharacterized protein.	GLUE N-terminal domain-containing protein.	0.647
A0A0E0S1S6	FG08545.1	A0A0E0S1S6	I1RW84	Uncharacterized protein.	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.	0.602
A0A0E0S1S6	FG09361.1	A0A0E0S1S6	I1RYB7	Uncharacterized protein.	Uncharacterized protein.	0.999