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| | hdrA | Heterodisulfide oxidoreductase, FAD-binding and iron-sulfur cluster-binding subunit A. (665 aa) |
| | hdrB | Heterodisulfide oxidoreductase, CCG domain pair-containing subunit B. (296 aa) |
| | hdrC | Heterodisulfide oxidoreductase, iron-sulfur cluster-binding subunit C. (194 aa) |
| | por | Pyruvate:ferredoxin/flavodoxin oxidoreductase. (1195 aa) |
| | hyaL | Periplasmically oriented, membrane-bound [NiFe]-hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (566 aa) |
| | hyaS | Periplasmically oriented, membrane-bound [NiFe]-hydrogenase small subunit. (371 aa) |
| | hemB | Porphobilinogen synthase; Belongs to the ALAD family. (325 aa) |
| | argD | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (417 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (266 aa) |
| | folD-1 | 5,10-methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (290 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase. (427 aa) |
| | GSU0357 | Cytochrome c nitrite reductase; 8 heme-binding sites; Belongs to the cytochrome c-552 family. (533 aa) |
| | ubiX | Menaquinone biosynthesis decarboxylase, putative; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (207 aa) |
| | sfrA | NADPH oxidoreductase, alpha subunit; NADPH-dependent Fe(3+) reductase. Probably involved in acetate metabolism and not in the reduction of Fe(3+) chelates. Unable to utilize NADH or formate as electron donors. Unlike formate dehydrogenases, contains no W, Mo or Se. Substrates are Fe(3+)- nitrilotriacetate >> Fe(3+)-citrate or Fe(3+)-EDTA > Fe(3+)- oxyhydroxide. Catalyzes also the reduction of NADP(+) with reduced methyl viologen as electron donor. No activity with menadione as electron acceptor. May be alternatively involved in transferring electrons from reduced ferredoxin to NADP(+) [...] (844 aa) |
| | sfrB | NADPH oxidoreductase, beta subunit; May catalyze the NADPH oxidation in the SfrAB NADPH-Fe(3+) oxidoreductase enzymatic complex. Probably involved in acetate metabolism and not in the reduction of Fe(3+) chelates. May serve as a major route for NADP regeneration. (672 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (282 aa) |
| | cysK | Cysteine synthase A. (307 aa) |
| | GSU0573 | Alcohol dehydrogenase, zinc-containing. (330 aa) |
| | ppdK | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (888 aa) |
| | prsA | Ribose-5-phosphate 1-pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa) |
| | fdnG | Periplasmically oriented, membrane-bound formate dehydrogenase, major subunit, selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1010 aa) |
| | fdnH | Periplasmically oriented, membrane-bound formate dehydrogenase, iron-sulfur cluster-binding subunit. (277 aa) |
| | hybS | Periplasmically oriented, membrane-bound [NiFe]-hydrogenase small subunit. (367 aa) |
| | hybL | Periplasmically oriented, membrane-bound [NiFe]-hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (560 aa) |
| | ppsA | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa) |
| | GSU0818 | Aldehyde dehydrogenase family 11 protein. (541 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (935 aa) |
| | folD-2 | 5,10-methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) |
| | acyP | Acylphosphatase. (91 aa) |
| | GSU0910 | Aldehyde:ferredoxin oxidoreductase, tungsten-containing. (601 aa) |
| | fumB | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (541 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (385 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa) |
| | gltA | Citrate synthase; Belongs to the citrate synthase family. (441 aa) |
| | frdC | Succinate dehydrogenase/fumarate reductase, cytochrome b558 subunit. (220 aa) |
| | frdA | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (637 aa) |
| | frdB | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. (253 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (542 aa) |
| | gltX | glutamyl-tRNA synthetase, non-discriminating; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (466 aa) |
| | GSU1238 | Iron-sulfur cluster-binding oxidoreductase. (149 aa) |
| | gdhA | Glutamate dehydrogenase, NADP-dependent; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (450 aa) |
| | pgi | Glucose-6-phosphate isomerase. (529 aa) |
| | GSU1313 | Carboxymuconolactone decarboxylase family protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (110 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | icd | Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family. (740 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (317 aa) |
| | korD | 2-oxoglutarate:ferredoxin oxidoreductase, ferredoxin subunit. (64 aa) |
| | korA | 2-oxoglutarate:ferredoxin oxidoreductase, alpha subunit. (377 aa) |
| | korB | 2-oxoglutarate:ferredoxin oxidoreductase, thiamin diphosphate-binding subunit. (273 aa) |
| | korC | 2-oxoglutarate:ferredoxin oxidoreductase, gamma subunit. (182 aa) |
| | GSU1550 | 4-oxalocrotonate tautomerase superfamily protein. (67 aa) |
| | GSU1564 | Glu/Leu/Phe/Val dehydrogenase superfamily protein. (990 aa) |
| | GSU1578 | (R)-methylmalonyl-CoA mutase, adenosylcobamide-binding subunit. (134 aa) |
| | GSU1590 | Phosphoesterase, putative. (316 aa) |
| | rpiB | Ribose-5-phosphate isomerase B. (148 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) |
| | gpmA | Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa) |
| | glcD-2 | D-lactate/glycolate dehydrogenase, FAD-binding protein, putative. (457 aa) |
| | glcF-2 | D-lactate/glycolate dehydrogenase, iron-sulfur cluster-binding protein, putative. (416 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | fbp | Fructose-1,6-bisphosphatase. (313 aa) |
| | acnB | Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (847 aa) |
| | hprA | Hydroxypyruvate reductase, putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa) |
| | hom | Homoserine dehydrogenase. (436 aa) |
| | thrC | Threonine synthase. (461 aa) |
| | maeB | Malate oxidoreductase, NADP-dependent, phosphate acetyltransferase-like domain-containing. (752 aa) |
| | GSU1702 | ROK domain transcriptional regulator/sugar kinase. (318 aa) |
| | pfk-1 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (363 aa) |
| | GSU1707 | Pyridoxal-5'-phosphate-dependent decarboxylase. (552 aa) |
| | apr | Adenosine-5'-phosphosulfate reductase, glutathione-dependent; Reduction of activated sulfate into sulfite. (235 aa) |
| | cysD | Sulfate adenylyltransferase, subunit 2. (267 aa) |
| | cysN | Sulfate adenylyltransferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (516 aa) |
| | paaK-1 | Phenylacetate--coenzyme A ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (433 aa) |
| | paaK-2 | Phenylacetate--coenzyme A ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (435 aa) |
| | GSU1799 | Aspartate 4-kinase; Belongs to the aspartokinase family. (405 aa) |
| | apgM | Phosphoglycerate mutase family protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (399 aa) |
| | glnA | Glutamine synthetase, type I. (470 aa) |
| | vorC | 2-oxoacid:ferredoxin oxidoreductase, gamma subunit. (179 aa) |
| | vorB | 2-oxoacid:ferredoxin oxidoreductase, thiamin diphosphate-binding subunit. (247 aa) |
| | vorA | 2-oxoacid:ferredoxin oxidoreductase, alpha subunit. (351 aa) |
| | vorD | 2-oxoacid:ferredoxin oxidoreductase, ferredoxin subunit. (67 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase component; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa) |
| | pfk-2 | 6-phosphofructokinase, ATP-dependent; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | cooF | Carbon monoxide dehydrogenase-associated iron-sulfur cluster-binding oxidoreductase CooF. (197 aa) |
| | cooS | Carbon monoxide dehydrogenase, catalytic subunit. (640 aa) |
| | GSU2191 | Aldehyde:ferredoxin oxidoreductase, tungsten-containing. (579 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (280 aa) |
| | mvhS | Methyl viologen-reducing hydrogenase, small subunit. (316 aa) |
| | mvhL | Methyl viologen-reducing hydrogenase, large subunit. (473 aa) |
| | pyc | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa) |
| | aceF | Pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide acetyltransferase. (418 aa) |
| | pdhB | Pyruvate dehydrogenase complex, E1 protein, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa) |
| | pdhA | Pyruvate dehydrogenase complex, E1 protein, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (325 aa) |
| | GSU2445 | Aconitate hydratase, putative. (645 aa) |
| | lpdA-1 | Dihydrolipoamide dehydrogenase. (472 aa) |
| | sucB | 2-oxoglutarate dehydrogenase, E2 protein, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (409 aa) |
| | sucA | 2-oxoglutarate dehydrogenase, E1 protein. (894 aa) |
| | cpkA | Carbamyl-phosphate synthetase, carbamate kinase-like protein. (314 aa) |
| | cysE-1 | Serine O-acetyltransferase. (225 aa) |
| | lpdA-2 | Dihydrolipoamide dehydrogenase. (452 aa) |
| | bkdA | Branched-chain 2-oxoacid dehydrogenase complex, E1 protein, alpha subunit, putative; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (352 aa) |
| | bkdB | Branched-chain 2-oxoacid dehydrogenase complex, E1 protein, beta subunit, putative. (320 aa) |
| | bkdF | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Branched-chain 2-oxoacid dehydrogenase complex, E2 protein, dihydrolipoamide acyltransferase, putative. (392 aa) |
| | pta | Phosphate acetyltransferase. (333 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (421 aa) |
| | nifK | Nitrogenase molybdenum-iron protein, beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. (489 aa) |
| | nifD | Nitrogenase molybdenum-iron protein, alpha chain. (479 aa) |
| | nifH | Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (289 aa) |
| | asd | Aspartate-4-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (367 aa) |
| | tklB | Transketolase, B protein. (314 aa) |
| | tklA | Transketolase, A protein. (277 aa) |
| | metF-2 | 5-methyltetrahydrofolate--homocysteine S-methyltransferase and 5,10-methylenetetrahydrofolate reductase. (605 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (214 aa) |
| | nfnA | NADH-dependent ferredoxin:NADP+ oxidoreductase, alpha subunit. (470 aa) |
| | mtd | Mannitol dehydrogenase. (352 aa) |
| | nrfA | Cytochrome c nitrite and sulfite reductase, catalytic subunit lipoprotein; 5 heme-binding sites; Belongs to the cytochrome c-552 family. (490 aa) |
| | nrfH | Cytochrome c nitrite and sulfite reductase, menaquinol-oxidizing subunit; 4 heme-binding sites. (154 aa) |
| | ltaA | L-allo-threonine aldolase, stereospecific. (348 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (513 aa) |
| | cysG | Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative. (224 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (434 aa) |
| | hemC | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (318 aa) |
| | hemD | Uroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase. (515 aa) |
| | glcD-1 | D-lactate/glycolate dehydrogenase, FAD-binding protein, putative. (459 aa) |
| | glcF-1 | D-lactate/glycolate dehydrogenase, iron-sulfur cluster-binding protein, putative. (421 aa) |
| | GSU3302 | (R)-methylmalonyl-CoA mutase, isobutyryl-CoA mutase-like catalytic subunit. (552 aa) |
| | mceE | methylmalonyl-CoA epimerase. (134 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase, GTP-dependent; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (618 aa) |
| | ltaE | L-threonine aldolase, low-specificity; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (351 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa) |
| | ackA-2 | Acetate kinase-related protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa) |
| | gltS | ferredoxin/NAD(P)H-dependent glutamate synthase, large subunit. (1510 aa) |
| | tpi | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa) |
