STRINGSTRING
Mbur_0499 Mbur_0499 Mbur_1843 Mbur_1843 Mbur_1864 Mbur_1864 Mbur_1882 Mbur_1882 pcm pcm Mbur_1924 Mbur_1924 mtbA-2 mtbA-2 Mbur_2122 Mbur_2122 Mbur_2163 Mbur_2163 ogt ogt Mbur_2243 Mbur_2243 Mbur_2244 Mbur_2244 mttB-2 mttB-2 mttB mttB ubiE ubiE cbiH cbiH cbiF cbiF cbiL cbiL cbiT cbiT Mbur_2422 Mbur_2422 Mbur_2433 Mbur_2433 Mbur_2446 Mbur_2446 mtrD mtrD mtrE mtrE Mbur_1539 Mbur_1539 flpA flpA Mbur_1562 Mbur_1562 Mbur_1590 Mbur_1590 Mbur_1600 Mbur_1600 Mbur_1602 Mbur_1602 Mbur_1616 Mbur_1616 Mbur_1623 Mbur_1623 Mbur_1672 Mbur_1672 cbiD cbiD Mbur_1754 Mbur_1754 Mbur_1776 Mbur_1776 mtrB mtrB mtrA mtrA mtrF mtrF mtrG mtrG mtrH mtrH Mbur_1481 Mbur_1481 Mbur_1469 Mbur_1469 Mbur_1468 Mbur_1468 Mbur_1449 Mbur_1449 Mbur_1437 Mbur_1437 Mbur_1284 Mbur_1284 Mbur_1222 Mbur_1222 rlmE rlmE Mbur_1149 Mbur_1149 cysGA cysGA Mbur_1090 Mbur_1090 thyA thyA Mbur_0979 Mbur_0979 dphB dphB trmY trmY rsmA rsmA hemK hemK cdhE cdhE Mbur_0814 Mbur_0814 Mbur_0812 Mbur_0812 Mbur_0808 Mbur_0808 Mbur_0767 Mbur_0767 trm1 trm1 Mbur_0651 Mbur_0651 Mbur_0483 Mbur_0483 Mbur_0364 Mbur_0364 Mbur_0256 Mbur_0256 Mbur_0165 Mbur_0165 Mbur_0084 Mbur_0084 mtrC mtrC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mbur_0499Methyltransferase; Evidence code ER4. (218 aa)
Mbur_1843N-6 DNA methylase; Evidence code ER2. (554 aa)
Mbur_1864Methyltransferase; Evidence code ER4. (221 aa)
Mbur_1882Protein of unknown function UPF0153; Evidence code ER4. (236 aa)
pcmprotein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (203 aa)
Mbur_1924Methyltransferase; Evidence code ER4. (291 aa)
mtbA-2Methylamine-specific methylcobamide:CoM methyltransferase; Evidence code ER2. (344 aa)
Mbur_2122Evidence code ER3; tRNA(m1A58)-methyltransferase. (250 aa)
Mbur_2163Protein with adenine-specific DNA methyltransferase domains; Evidence code ER4. (1104 aa)
ogtMethylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (168 aa)
Mbur_2243Methyltransferase MtxX; Evidence code ER4. (285 aa)
Mbur_2244Fusion of Tetrahydromethanopterin S-methyltransferase subunits A and H; Evidence code ER3. (453 aa)
mttB-2Trimethylamine methyltransferase; Catalyzes the transfer of a methyl group from trimethylamine to the corrinoid cofactor of MttC. (497 aa)
mttBTrimethylamine methyltransferase; Evidence code ER3; Belongs to the trimethylamine methyltransferase family. (484 aa)
ubiEMenaquinone biosynthesis methyltransferase; Evidence code ER3. (208 aa)
cbiHCobalt-precorrin-3B C(17)-methyltransferase; Evidence code ER2. (267 aa)
cbiFCobalt-precorrin-4 C(11)-methyltransferase; Evidence code ER2. (243 aa)
cbiLCobalt-precorrin-2 C(20)-methyltransferase; Evidence code ER3; Belongs to the precorrin methyltransferase family. (203 aa)
cbiTcobalt-precorrin-6Y C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. (183 aa)
Mbur_2422Radical SAM protein with DUF512 domain; Evidence code ER4. (409 aa)
Mbur_2433RNA methyltransferase; Evidence code ER3. (231 aa)
Mbur_2446SAM-dependent methyltransferase; Evidence code ER3. (357 aa)
mtrDTetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (239 aa)
mtrETetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrE family. (301 aa)
Mbur_1539DNA-cytosine methyltransferase; Evidence code ER3; MthTIM-like; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (569 aa)
flpAFibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (230 aa)
Mbur_1562Pre-mRNA processing ribonucleoprotein; Evidence code ER3. (354 aa)
Mbur_1590Methyltransferase; Evidence code ER4. (236 aa)
Mbur_1600Methyltransferase; Evidence code ER4. (323 aa)
Mbur_1602Radical SAM protein with Cobalamin (vitamin B12)-binding domain; Evidence code ER4. (487 aa)
Mbur_1616Methyltransferase; Evidence code ER4. (238 aa)
Mbur_1623Nucleic acid binding protein; Evidence code ER4. (344 aa)
Mbur_1672Protein of unknown function DUF166; Evidence code ER4. (223 aa)
cbiDCobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (340 aa)
Mbur_1754Hypothetical protein; Evidence code ER5. (346 aa)
Mbur_1776Protein of unknown function UPF0313; Evidence code ER4. (622 aa)
mtrBTetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (107 aa)
mtrATetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (241 aa)
mtrFTetrahydromethanopterin S-methyltransferase subunit F; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (79 aa)
mtrGTetrahydromethanopterin S-methyltransferase subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (75 aa)
mtrHTetrahydromethanopterin S-methyltransferase subunit H; Evidence code ER2. (318 aa)
Mbur_1481Protein of unknown function DUF166; Evidence code ER4. (250 aa)
Mbur_1469Radical SAM family protein with UPF0004 domain; Evidence code ER4. (368 aa)
Mbur_1468UPF0153-domain protein; Evidence code ER4. (229 aa)
Mbur_1449Methyltransferase; Evidence code ER4. (226 aa)
Mbur_1437RNA methyltransferase; Evidence code ER2. (203 aa)
Mbur_1284Protein of unknown function DUF343; Evidence code ER4. (60 aa)
Mbur_1222N-6 DNA methylase; Evidence code ER3; Restriction-Modification system protein. (519 aa)
rlmERibosomal RNA large subunit methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (267 aa)
Mbur_1149UPF0026, Radical SAM protein; Evidence code ER4. (326 aa)
cysGAUroporphyrinogen-III C-methyltransferase; Evidence code ER2; SUMT; Belongs to the precorrin methyltransferase family. (250 aa)
Mbur_1090Methyltransferase; Evidence code ER4. (283 aa)
thyAThymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. (217 aa)
Mbur_0979RNA-binding S4 domain protein; Evidence code ER4. (225 aa)
dphBDiphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. (267 aa)
trmYProtein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (202 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (270 aa)
hemKN5-glutamine methyltransferase; Evidence code ER3. (202 aa)
cdhEAcetyl-CoA decarbonylase/synthase complex gamma subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. (468 aa)
Mbur_0814Methanol--corrinoid methyltransferase; Evidence code ER2. (461 aa)
Mbur_0812Methanol--corrinoid methyltransferase; Evidence code ER2. (462 aa)
Mbur_0808Methanol-specific methylcobalamin:CoM methyltransferase; Evidence code ER2. (338 aa)
Mbur_0767Methyltransferase domain protein; Evidence code ER4. (496 aa)
trm1N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (388 aa)
Mbur_0651Methyltransferase; Evidence code ER4. (131 aa)
Mbur_0483N-6 DNA methylase; Evidence code ER3; Restriction-Modification system protein. (568 aa)
Mbur_0364CheR methyltransferase-like chemotaxis protein; Evidence code ER3. (270 aa)
Mbur_0256Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (178 aa)
Mbur_0165Methyltransferase; Evidence code ER4. (283 aa)
Mbur_0084Methyltransferase; Evidence code ER4. (208 aa)
mtrCTetrahydromethanopterin S-methyltransferase subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (269 aa)
Your Current Organism:
Methanococcoides burtonii
NCBI taxonomy Id: 259564
Other names: M. burtonii DSM 6242, Methanococcoides burtonii DSM 6242, Methanococcoides burtonii str. DSM 6242
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.