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AAZ69393.1 AAZ69393.1 AAZ69618.1 AAZ69618.1 AAZ69619.1 AAZ69619.1 AAZ69655.1 AAZ69655.1 AAZ69685.1 AAZ69685.1 mcrA mcrA mcrG mcrG mcrC mcrC mcrD mcrD mcrB mcrB mtrH mtrH mtrG mtrG mtrF mtrF mtrA mtrA mtrB mtrB mtrC mtrC mtrD mtrD mtrE mtrE AAZ70508.1 AAZ70508.1 AAZ70509.1 AAZ70509.1 hdrE hdrE hdrD hdrD AAZ70655.1 AAZ70655.1 AAZ70890.1 AAZ70890.1 AAZ70891.1 AAZ70891.1 AAZ70892.1 AAZ70892.1 mtxH mtxH mtxA mtxA AAZ71500.1 AAZ71500.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AAZ69393.1Tetrahydromethanopterin S-methyltransferase, subunit A. (188 aa)
AAZ69618.1CoB--CoM heterodisulfide reductase subunit B. (300 aa)
AAZ69619.1CoB--CoM heterodisulfide reductase subunit C. (161 aa)
AAZ69655.1Methylcoenzyme M reductase system, component A2. (584 aa)
AAZ69685.1ABC transporter, ATP-binding protein. (537 aa)
mcrAMethyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (570 aa)
mcrGMethyl-coenzyme M reductase, gamma subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (248 aa)
mcrCMethyl coenzyme M reductase, subunit D. (206 aa)
mcrDMethyl coenzyme M reductase, subunit C. (171 aa)
mcrBMethyl-coenzyme M reductase, beta subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (434 aa)
mtrHTetrahydromethanopterin S-methyltransferase, subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA. (316 aa)
mtrGTetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (72 aa)
mtrFTetrahydromethanopterin S-methyltransferase, subunit F; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (73 aa)
mtrATetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (240 aa)
mtrBTetrahydromethanopterin S-methyltransferase, subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (108 aa)
mtrCTetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (267 aa)
mtrDTetrahydromethanopterin S-methyltransferase, subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (250 aa)
mtrETetrahydromethanopterin S-methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (302 aa)
AAZ70508.1Formate dehydrogenase, alpha subunit (F420). (695 aa)
AAZ70509.1Formate dehydrogenase, beta subunit (F420). (401 aa)
hdrECoB-CoM heterodisulfide reductase, subunit E; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane. (259 aa)
hdrDCoB-CoM heterodisulfide reductase, subunit D; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (409 aa)
AAZ70655.1Tetrahydromethanopterin S-methyltransferase, subunit A. (182 aa)
AAZ70890.1CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (806 aa)
AAZ70891.1Heterodisulfide reductase subunit HdrC. (236 aa)
AAZ70892.1Heterodisulfide reductase, subunit B. (314 aa)
mtxHTetrahydromethanopterin S-methyltransferase, subunit H. (310 aa)
mtxATetrahydromethanopterin S-methyltransferase, subunit A. (197 aa)
AAZ71500.1CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (792 aa)
Your Current Organism:
Methanosarcina barkeri Fusaro
NCBI taxonomy Id: 269797
Other names: M. barkeri str. Fusaro, Methanosarcina barkeri DSM 804, Methanosarcina barkeri str. Fusaro, Methanosarcina barkeri strain Fusaro
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