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| | PAB2390 | Sun/NOL1/NOP nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (450 aa) |
| | PAB0042 | Conserved archaebacterial protein, DUF88 family. (191 aa) |
| | PAB0043 | Conserved archaebacterial protein, DUF88 family. (162 aa) |
| | PAB0046 | Hypothetical protein, sharing a conserved domain with thiamine biosynthesis protein thiI. (355 aa) |
| | PAB0051 | Hypothetical protein sharing a conserved domain with thiamine biosynthesis protein thiI. (158 aa) |
| | cca | Cca tRNA nucleotidyltransferase (CCA adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (448 aa) |
| | PAB0066 | alaRS-like alanyl-tRNA synthetase related protein (fragment). (213 aa) |
| | fau-1 | Ribonuclease E homolog, putative; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. (481 aa) |
| | PAB0082 | Queuine tRNA-ribosyltransferase. (570 aa) |
| | PAB0124 | Predicted GTPase or GTP-binding protein; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA (By similarity). (357 aa) |
| | lysS | lysS lysyl-tRNA synthetase. (526 aa) |
| | PAB0165 | SAM-dependent methyltransferase, putative. (248 aa) |
| | tiaS | Predicted DNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (422 aa) |
| | ksgA | ksgA dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (269 aa) |
| | PAB0263 | Conserved archaebacterial protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (204 aa) |
| | PAB0278 | RNA binding protein, emap domain. (109 aa) |
| | pimT-like | SAM-dependent methyltransferase, putative; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T- loop of some tRNAs. Methylates the first adenine of an AA sequence. Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family. (253 aa) |
| | dnaG | Primase dnaG-like; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (447 aa) |
| | gltX | gltX glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa) |
| | rnhB | rnhB ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (224 aa) |
| | trub | truB tRNA pseudouridine synthase II; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (334 aa) |
| | glyS | glyS glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (571 aa) |
| | rtcB | rtcB homolog, intein containing; GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends; Belongs to the RtcB family. (916 aa) |
| | rnp4 | RNAse P protein subunit RPR2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (117 aa) |
| | rrp4 | Predicted exosome subunit, RNA-binding protein rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (265 aa) |
| | rph | Rph ribonuclease PH, exosome complex exonuclease; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails (Probable). (249 aa) |
| | rrp42 | RNAse PH-related exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (274 aa) |
| | rpoB | rpoB DNA-directed RNA polymerase, subunit B (EC 2.7.7.6); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1117 aa) |
| | rpoA1 | rpoA1 DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (907 aa) |
| | rpoA2 | rpoA2 DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (397 aa) |
| | nusA | nusA transcription termination-antitermination factor nusA, putative; Participates in transcription termination. Belongs to the NusA family. (145 aa) |
| | truD | Hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (406 aa) |
| | rpl7AE | rpl7AE LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (128 aa) |
| | rnp2 | RNAse P subunit P14 ortholog; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (119 aa) |
| | pelA | pelA cell division protein pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (356 aa) |
| | argS | argS arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (625 aa) |
| | trm5b | Hypothetical protein, Met-10+ like protein; Specifically methylates the N1 position of guanosine-37 in various tRNAs. (330 aa) |
| | PAB0523 | Nucleolar protein from the nop2 family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (311 aa) |
| | thiI-like | thiI-like thiamin biosynthesis protein. (306 aa) |
| | taw3-1 | Hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (194 aa) |
| | ileS | ileS isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1067 aa) |
| | aspS | aspS aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (438 aa) |
| | PAB0719 | RNA methyltransferase, putative; Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (405 aa) |
| | rnz | Putative sulfatase, ATSA/ELAC family; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (307 aa) |
| | PAB0732 | rpoF DNA-directed RNA polymerase, subunit F. (121 aa) |
| | tgtA | Queuine-archaeosine tRNA ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (584 aa) |
| | PAB0760 | RNA methyltransferase, putative; Catalyzes the formation of 5-methyl-uridine at position equivalent to 747 (m5U747) in 23S rRNA (m5U859 in the P.abyssi numbering). (410 aa) |
| | vapC | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (169 aa) |
| | PAB0830 | Sun/NOL1/NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (449 aa) |
| | PAB0880 | Hypothetical protein. (369 aa) |
| | serS | serS seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (455 aa) |
| | nob1 | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family. (161 aa) |
| | PAB0923 | Putative RNA methylase, UPF0020 family. (363 aa) |
| | cysS | cysS cysteinyl-tRNA synthetase. (477 aa) |
| | tfe | Probable archaeal transcription factor, related to transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing [...] (190 aa) |
| | PAB1040 | Uncharacterized ArCR; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs. Belongs to the aTrm56 family. (198 aa) |
| | bud32 | Hypothetical protein; Component of the KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Bud32 has ATPase activity in the context of the KEOPS complex and likely plays a supporting role to the catalytic subunit Kae1. Belongs to the protein kinase superfamily. BUD32 family. (220 aa) |
| | PAB1092 | Predicted ATPase of the PP-loop superfamilyl. (303 aa) |
| | endA | Archaeal tRNA intron endonuclease (EC 3.1.27.9); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (170 aa) |
| | hisS | hisS histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa) |
| | rpoE1 | rpoE1 DNA-directed RNA polymerase, subunit E'. (188 aa) |
| | trpS | trpS tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (385 aa) |
| | PAB1134 | Hypothetical protein, UPF0004 family; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. (425 aa) |
| | rnp3 | Ribonuclease P subunit rpp30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (212 aa) |
| | gcp | Gcp O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. In vitro, binds tRNA, ssRNA, both single- and double-stranded DNA, and exhibits a low ATPase activity. Belongs [...] (324 aa) |
| | PAB1173 | Sun/NOL1/NOP nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (385 aa) |
| | PAB1190 | alaRS-like alanyl-tRNA synthetase related protein (fragment). (405 aa) |
| | PAB1237 | Hypothetical protein, Met-10+ like protein. (396 aa) |
| | alaS | alaS alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (914 aa) |
| | valS | valS valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (891 aa) |
| | trmG10 | Methylase, puative RNA modification protein; Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs. Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G). (332 aa) |
| | sua5 | Putative translation factor, SUA5 related protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Likely catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Does not bind tRNA. (340 aa) |
| | PAB1440 | alaRS-like alanyl-tRNA synthetase related protein (fragment). (159 aa) |
| | PAB1464 | Tfs archaeal transcription factor S; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (110 aa) |
| | thrS | thrS threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) (Probable). Edits incorrectly charged L-seryl-tRNA(Thr) via its editing domain. Deacylates correctly charged glycyl-tRNA(Gly), but neither glycyl-tRNA(Gly)(2'-dA76) (the terminal 2'-OH of tRNA(Thr) adenine 76 has been replaced by hydrogen) nor the 2'-fluoro tRNA derivative do so, strongly suggesting the editing function is tRNA catalyzed. Belongs to the class-II aminoacyl-tR [...] (625 aa) |
| | nusA-2 | Hypothetical protein, containing KH nucleic acid binding domain. (170 aa) |
| | PAB1512 | Hypothetical protein. (124 aa) |
| | PAB1517 | Tfx DNA binding protein; Putative transcriptional regulator. (145 aa) |
| | cgi121 | Hypothetical protein; Component of the KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Cgi121 acts as an allosteric effector that regulates the t(6)A activity of the complex. Cgi121 is not required for tRNA modification. (171 aa) |
| | taw2 | Hypothetical protein, Met-10+ like protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (278 aa) |
| | PAB1540 | Hypothetical protein, containing potential zinc-binding domain; Belongs to the UPF0148 family. (105 aa) |
| | PAB1546 | Hypothetical protein. (156 aa) |
| | vapC-2 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (148 aa) |
| | PAB1672 | Predicted nucleic acid-binding protein, contains PIN domain. (143 aa) |
| | truA | truA pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (263 aa) |
| | proS | proS prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa) |
| | tbp | TATA box binding protein TFIIB-BBRE complex, chain A; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity). (191 aa) |
| | tyrS | tyrS tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (375 aa) |
| | rnj | Metallo-beta-lactamase superfamily protein; A highly processive 5'-3' exoribonuclease; no evidence has been seen for endonuclease activity. Prefers 5'-phosphate or 5'- hydroxyl ends; 5'-triphosphate substrates are very poorly degraded, does not degrade circular RNA. Does not degrade pre-tRNA(Trp) suggesting it is inhibited by strong secondary structures. Also degrades ssNDA but not dsDNA. (451 aa) |
| | leuS | leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (967 aa) |
| | nep1 | Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA (By similarity). (232 aa) |
| | trmY | Hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (204 aa) |
| | fen | Fen1 FLAP endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathw [...] (343 aa) |
| | tfb | TATA box binding protein TFIIB-BBRE complex, chain B; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (300 aa) |
| | rtcA | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). (342 aa) |
| | PAB1946 | Hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity). Chaperone or modulator of proteins involved in DNA or RNA processing. Protects the tRNA (cytosine-5-)- methyltransferase PAB1947 against aggregation and increases its specificity; Belongs to the archease family. (142 aa) |
| | PAB1947 | Sun/NOL1/NOP2 nucleolar protein; Catalyzes AdoMet-dependent formation of m5C in tRNA. In the presence of protein archease, specifically methylates the cytosine at position 49 (m5C49) of tRNA. In the absence of archease, catalyzes the formation of m5C at many locations in tRNAs or rRNAs. (311 aa) |
| | PAB2029 | Predicted ATPase of the PP-loop superfamily. (323 aa) |
| | taw1 | Radical SAM family protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (342 aa) |
| | trm1 | TRM1 N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (383 aa) |
| | rnp1 | RNAse P protein subunit P29/POP4; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (127 aa) |
| | taw3-2 | Hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (206 aa) |
| | asnS | asnS asparaginyl-tRNA synthetase (EC 6.1.1.22) (asparagine--tRNA ligase) (ASNRS); Belongs to the class-II aminoacyl-tRNA synthetase family. (434 aa) |
| | priL | Eukaryotic-type DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. Displays gap-filling and strand-displacement activities. (393 aa) |
| | priS | DNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own, synthesizing DNA strands up to 3 kB. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability for RNA fragments up to 150 bases. The DNA polymerase activity may enable DNA primase t [...] (345 aa) |
| | kptA | Probable RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity). (183 aa) |
| | vapC-3 | Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (128 aa) |
| | taw22 | Hypothetical protein, Met-10+ like protein; Catalyzes both the N1-methylation of guanosine and the C7- methylation of 4-demethylwyosine (imG-14) at position 37 in tRNA(Phe). (333 aa) |
| | flpA | Fibrillarin pre-rRNA splicing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (227 aa) |
| | csl4 | RNA-binding protein, putative, containing S1 RNA binding domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (199 aa) |
| | rpoL | rpoL DNA-directed RNA polymerase, subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (95 aa) |
| | PAB2339 | Hypothetical protein. (140 aa) |
| | dtdA | Hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. Catalyzes the hydrolysis of D- tyrosyl-tRNA(Tyr) and D-aspartyl-tRNA(Asp). (272 aa) |
| | asnS-like | asnS-like asparaginyl-tRNA synthetase related protein. (294 aa) |
| | PAB2357 | Component of the U3 small nucleolar ribonucleoprotein, imp4 homolog; Probably involved in the biogenesis of the ribosome. (224 aa) |
| | metS | metS methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (722 aa) |
| | pus10 | Hypothetical protein, containing THUMP domain; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (393 aa) |
| | rpoD | rpoD DNA-directed RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (259 aa) |
| | PAB2425 | Translin homolog, putative. (209 aa) |
| | pheS | pheS phenylalanyl-tRNA synthetase, subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (500 aa) |
| | pheT | pheT phenylalanyl-tRNA synthetase, subunit beta. (556 aa) |
| | tmcA | Acetyltransferase (GNAT) family, containing ATP/GTP-binding site motif A; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (817 aa) |
| | rpoP | rpoP DNA-directed RNA polymerase, subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (49 aa) |
| | pcc1 | Hypothetical protein; Component of the KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Pcc1 functions as a dimerization module for the complex. (77 aa) |
| | PAB3084 | Hypothetical protein. (94 aa) |
| | rpoN | rpoN DNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (65 aa) |
| | rpoK | rpoK DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (57 aa) |
| | rpoH | rpoH DNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (82 aa) |
| | nop10 | Small nucleolar ribonucleoprotein, trans-acting factor intervening in ribosome biogenesis; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (60 aa) |
